Blood Pressure

[TRENdy07]

Forget amlodipine. You're clearly sensitive to edema and don't want to accumulate damage.

Because nebiv lowers BP by two mechanisms, heart rate reduction on nitrous oxide induced relaxation of blood vessels it important to figure out if one or both of those effects are what's making it work for you, when considering alternatives.

The reason is essentially no other BP med or combo offers both effects. Which makes your options somewhat limited.

What other drugs have you tried to lower bp?

Is your heart rate normally high?

Have you used other beta blockers before? Did they lower your bp? Was nebiv the first thing that worked?

Having a strong response to nebivolol and not other bp meds suggest either high aldosterone (driving high cardiac output) or seriously dysfunctional endothelium in your blood vessels preventing nitrous oxide release (hardened arteries from diabetes or severe plaque buildup).

Aldosterone has recently become recognized as a major driver of treatment resistant bp. You can have that easily tested(and you should for reasons below) , and a new drug that lowers production of that hormone to normal levels has shown amazing results. Instead of taking a combo of bp drugs, just reducing aldosterone into normal range brings bp into normal range and significantly improves heart and kidney function. which are all under stress when aldosterone is too high.

Although high aldosterone can be genetic, it can be a sign of other problems, from relatively benign. like potassium deficiency, to adrenal tumors, kidney or liver disease so you should take the opportunity to get it checked, just in case.

I have not tried many. I tried cialis alone and it didn’t budge. Tried telmisartan alone and it didn’t budge (lowered my hct significantly) Read a lot of good things on the forums about nebivolol despite’s it being a beta blocker. Ordered some and it helped so I rolled with that for a while. Recently read good things about the combo of telmaheal 40 am and decided to try some since I was running low on nebivolol. I think I may need to bite the bullet and seek a doctors care so I can see what works for me and what doesn’t. In the meantime, I guess I’m going to order more nebivolol. Just sucks because I’ll have to wait for a couple weeks to receive it.

To answer the heart rate thing. I don’t have high rhr naturally. It elevates on blast and even more so on hgh. Nebivolol significantly lowered my rhr. It’s basically the only way I felt comfortable running hgh and high-ish doses of test/primo. I appreciate the feedback

 

[Ghoul]

I have not tried many. I tried cialis alone and it didn’t budge. Tried telmisartan alone and it didn’t budge (lowered my hct significantly) Read a lot of good things on the forums about nebivolol despite’s it being a beta blocker. Ordered some and it helped so I rolled with that for a while. Recently read good things about the combo of telmaheal 40 am and decided to try some since I was running low on nebivolol. I think I may need to bite the bullet and seek a doctors care so I can see what works for me and what doesn’t. In the meantime, I guess I’m going to order more nebivolol. Just sucks because I’ll have to wait for a couple weeks to receive it.

To answer the heart rate thing. I don’t have high rhr naturally. It elevates on blast and even more so on hgh. Nebivolol significantly lowered my rhr. It’s basically the only way I felt comfortable running hgh and high-ish doses of test/primo. I appreciate the feedback

That's a good idea. I strongly suggest asking for an aldosterone / renin test "because you read it's frequently the cause of treatment resistant hypertension." Cardiologists will be familiar with these recent developments, but primary care doctors are unlikely to. Could shortcut a lot of unnecessary troubleshooting if yours is high.

 

[Lifting88]

Forget amlodipine. You're clearly sensitive to edema and don't want to accumulate damage.

Because nebiv lowers BP by two mechanisms, heart rate reduction on nitrous oxide induced relaxation of blood vessels it important to figure out if one or both of those effects are what's making it work for you, when considering alternatives.

The reason is essentially no other BP med or combo offers both effects. Which makes your options somewhat limited.

What other drugs have you tried to lower bp?

Is your heart rate normally high?

Have you used other beta blockers before? Did they lower your bp? Was nebiv the first thing that worked?

Having a strong response to nebivolol and not other bp meds suggest either high aldosterone (driving high cardiac output) or seriously dysfunctional endothelium in your blood vessels preventing nitrous oxide release (hardened arteries from diabetes or severe plaque buildup).

Aldosterone has recently become recognized as a major driver of treatment resistant bp. You can have that easily tested(and you should for reasons below) , and a new drug that lowers production of that hormone to normal levels has shown amazing results. Instead of taking a combo of bp drugs, just reducing aldosterone into normal range brings bp into normal range and significantly improves heart and kidney function. which are all under stress when aldosterone is too high.

Although high aldosterone can be genetic, it can be a sign of other problems, from relatively benign. like potassium deficiency, to adrenal tumors, kidney or liver disease so you should take the opportunity to get it checked, just in case.

Where to find this medicine
Name/brand maybe

 

[Ghoul]

Where to find this medicine
Name/brand maybe

It's called Baxdostat, and will be available in a few months.

'Game-changing' miracle drug set to slash high blood pressure

The medicine, hailed as a 'triumph of science', is the first to tackle the underlying cause of hypertension rather than simply dealing with its symptoms.

www.dailymail.co.uk

They say this may be the only drug needed to fix hypertension in over 500 million people, without side effects.

 

[Ghoul]

*sorry "baxdRostat"

New drug hailed as ‘gamechanger’ in tackling stubbornly high blood pressure

Trials of baxdrostat have produced ‘exciting’ results for people whose hypertension has proved difficult to control

www.theguardian.com

 

[Optimizaa28]

Either increase the olmesartan or switch to telmisartan. Telmisartan is often cited and preferred by AAS users.

 

[TRENdy07]

That's a good idea. I strongly suggest asking for an aldosterone / renin test "because you read it's frequently the cause of treatment resistant hypertension." Cardiologists will be familiar with these recent developments, but primary care doctors are unlikely to. Could shortcut a lot of unnecessary troubleshooting if yours is high.

One already ordered one from privatemd labs. In the meantime. I’m going to get back on cruise and nebivolol and make an appointment with a cardiologist

 

[Ghoul]

One already ordered one from privatemd labs. In the meantime. I’m going to get back on cruise and nebivolol and make an appointment with a cardiologist

I don't recall seeing your lipids posted anywhere, but if you're seeing a cardiologist anyway, and you're over 70 LDL, hit him up for Pitavastatin. It's a pain in the ass trying to get it out of primary care docs, since most haven't heard of it.

Was with a friend using Sesame telehealth to get a prescription for it the other day, and the provider told him she was a Cardiac nurse and never heard of Pitavastatin before, lol. She was impressed after looking it up.

If you're over 100 LDL, Repatha just, as in a few days ago, got approved by the FDA for anyone with LDL over 100 and an additional risk factor like hypertension. So if you have insurance, you could get that approved pretty easily now compared to the past, if you were interested.

 

[Lifting88]

Either increase the olmesartan or switch to telmisartan. Telmisartan is often cited and preferred by AAS users.

Olmesartan is stronger in reducing bloodpressure then telma

 

[Lifting88]

*sorry "baxdRostat"

New drug hailed as ‘gamechanger’ in tackling stubbornly high blood pressure

Trials of baxdrostat have produced ‘exciting’ results for people whose hypertension has proved difficult to control

www.theguardian.com

Nice but will take some time before we can buy it i guess

 

[Optimizaa28]

Olmesartan is stronger in reducing bloodpressure then telma

Did not know this. Half-life is also something to consider, is that better too?

 

[Lifting88]

I don't recall seeing your lipids posted anywhere, but if you're seeing a cardiologist anyway, and you're over 70 LDL, hit him up for Pitavastatin. It's a pain in the ass trying to get it out of primary care docs, since most haven't heard of it.

Was with a friend using Sesame telehealth to get a prescription for it the other day, and the provider told him she was a Cardiac nurse and never heard of Pitavastatin before, lol. She was impressed after looking it up.

If you're over 100 LDL, Repatha just, as in a few days ago, got approved by the FDA for anyone with LDL over 100 and an additional risk factor like hypertension. So if you have insurance, you could get that approved pretty easily now compared to the past, if you were interested.

Can i ask why you prefer pita over rosuvastine

Im on rosu from me doc and was checking for pita but rosu is alot cheaper and lowers ldl mord then pita
Pita raise hdl more from what i read about it

 

[Ateam2023]

I don't recall seeing your lipids posted anywhere, but if you're seeing a cardiologist anyway, and you're over 70 LDL, hit him up for Pitavastatin. It's a pain in the ass trying to get it out of primary care docs, since most haven't heard of it.

Was with a friend using Sesame telehealth to get a prescription for it the other day, and the provider told him she was a Cardiac nurse and never heard of Pitavastatin before, lol. She was impressed after looking it up.

If you're over 100 LDL, Repatha just, as in a few days ago, got approved by the FDA for anyone with LDL over 100 and an additional risk factor like hypertension. So if you have insurance, you could get that approved pretty easily now compared to the past, if you were interested.

so in my situation, my ldl is @90 ish, and i would like to know your opinion on what a good medication should i look into? My bp is controlled and not high at all, averaging 130/65-70, seems like my lower number is always between 60-70 , but i also have a little brother whos ldl is @135, Thanks for any advice.

 

[TRENdy07]

I don't recall seeing your lipids posted anywhere, but if you're seeing a cardiologist anyway, and you're over 70 LDL, hit him up for Pitavastatin. It's a pain in the ass trying to get it out of primary care docs, since most haven't heard of it.

Was with a friend using Sesame telehealth to get a prescription for it the other day, and the provider told him she was a Cardiac nurse and never heard of Pitavastatin before, lol. She was impressed after looking it up.

If you're over 100 LDL, Repatha just, as in a few days ago, got approved by the FDA for anyone with LDL over 100 and an additional risk factor like hypertension. So if you have insurance, you could get that approved pretty easily now compared to the past, if you were interested.

Haven’t tested my lipids in a while. They are usually fine….. but I just got done with a tren cycle soooooo

 

[Bigoldguy]

so in my situation, my ldl is @90 ish, and i would like to know your opinion on what a good medication should i look into? My bp is controlled and not high at all, averaging 130/65-70, seems like my lower number is always between 60-70 , but i also have a little brother whos ldl is @135, Thanks for any advice.

Nust curious if youre taking fish oil? My ldl was cut by 15-20 pts when I started taking it and my hdl jumped up 5-10 pts.

 

[Ateam2023]

Nust curious if youre taking fish oil? My ldl was cut by 15-20 pts when I started taking it and my hdl jumped up 5-10 pts.

yes , i take 3 g of fish oil daily

 

[Ateam2023]

Nust curious if youre taking fish oil? My ldl was cut by 15-20 pts when I started taking it and my hdl jumped up 5-10 pts.

how much are you taking?

 

[Bigoldguy]

how much are you taking?

4 g

 

[Lifting88]

so in my situation, my ldl is @90 ish, and i would like to know your opinion on what a good medication should i look into? My bp is controlled and not high at all, averaging 130/65-70, seems like my lower number is always between 60-70 , but i also have a little brother whos ldl is @135, Thanks for any advice.

I think 130 isnt controlled its not very high but 110/120 would be better

 

[malfeasance]

Speaking of aldosterone, it's the next "big thing" in hypertension. A major overlooked cause (having trouble lowering BP with "normal" meds like ARBs and CCBs is strong sign aldosterone is involved).

Here's a recent important bp treatment guideline update your primary care physician probobly won't catch up with for another 10 years, but you can do yourself ($70 aldosterone/renin at ultalabs, or request from your doc):

Screen All With Hypertension for Primary Aldosteronism

In a new clinical practice guideline, the Endocrine Society advises universal screening of those with hypertension by measuring renin and aldosterone.

www.medscape.com

So diuretics like aldactone?