What's the largest test only cycle you ran, and what were your results?

It seems we're of the same mind in terms of gear philosophy.

I was planning on running a Tren + E2 Cyp only blast and posting here.
If you look at the evidence behind it, it makes a lot of sense.

There are multiple papers showing that Tren is cardioprotective and suggesting it as an alternative to TRT due to reduced androgenic activity.

(Doses used were 2mg/kg, human-equivalent roughly = 0.325mg/kg. Something like 30-35mg/day (210-245mg/wk) for a 90-110kg person)



Research Evidence:

17β-Hydroxyestra-4,9,11-trien-3-one (trenbolone) exhibits tissue selective anabolic activity: effects on muscle, bone, adiposity, hemoglobin, and prostate



Improvements in body composition, cardiometabolic risk factors and insulin sensitivity with trenbolone in normogonadic rats

  • Trenbolone decreased fat mass by 37% and increased lean mass by 11%
  • No evidence of adverse cardiac (e.g., no fibrosis or impaired ischemia tolerance) or hepatic effects

Trenbolone Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic Syndrome

  • Reduced subcutaneous and visceral fat accumulation, hypertriglyceridemia, hypercholesterolemia, hyperinsulinemia, and myocardial damage compared to untreated deficient rats
  • Improved myocardial tolerance to ischemia-reperfusion injury, suggesting cardioprotective effects
  • Metabolic benefits included better insulin sensitivity and lipid profiles
Any idea why Tren produces reduced cardio Capacity in humans?
 
To add my own experience:

Ran a 1.2g Test E + 500mg Mast E blast, was pretty much what you'd expect. Great progress. Felt good, no sides.

Will be starting 1.2g Test + 1.2g Deca in a few weeks.

Any idea why Tren produces reduced cardio Capacity in humans?

Curious what you mean by reduced cardio capacity?

As in, aerobic exercise is more difficult on Tren? I've heard a few people mention this anecdotally, though I've not had this experience personally.

From a pharmacological standpoint, I'm not sure I can offer any ideas. And as far I've seen from the literature, there's nothing examining this specifically.

I can look for studies where Tren was administered to rodents and they had them perform wheel-running, that might offer an idea at least.
 
To add my own experience:

Ran a 1.2g Test E + 500mg Mast E blast, was pretty much what you'd expect. Great progress. Felt good, no sides.

Will be starting 1.2g Test + 1.2g Deca in a few weeks.



Curious what you mean by reduced cardio capacity?

As in, aerobic exercise is more difficult on Tren? I've heard a few people mention this anecdotally, though I've not had this experience personally.

From a pharmacological standpoint, I'm not sure I can offer any ideas. And as far I've seen from the literature, there's nothing examining this specifically.

I can look for studies where Tren was administered to rodents and they had them perform wheel-running, that might offer an idea at least.
Yes - pretty much everyone I’ve ever seen who runs tren reports reduced capacity for cardiovascular exercise. Perhaps it’s from the impact of other compounds theyre running? Or dose dependent? Maybe from prostaglandins?
 
Yes - pretty much everyone I’ve ever seen who runs tren reports reduced capacity for cardiovascular exercise. Perhaps it’s from the impact of other compounds theyre running? Or dose dependent? Maybe from prostaglandins?
It'd be interesting to see objective data on this, something like a VO2 max test performed before/after Tren-only blast.

I know the folklore is that Montelukast is supposed to alleviate this. It's a leukotriene antagonist, and leukotrienes are produced as part of immune function.

Maybe some sort of inflammatory/immune response to Tren? I have nothing to back up this idea but it's the only thing I could reasonably think of.
 
It'd be interesting to see objective data on this, something like a VO2 max test performed before/after Tren-only blast.

I know the folklore is that Montelukast is supposed to alleviate this. It's a leukotriene antagonist, and leukotrienes are produced as part of immune function.

Maybe some sort of inflammatory/immune response to Tren? I have nothing to back up this idea but it's the only thing I could reasonably think of.
I’ve heard of folks using Zyrtec to combat some Tren sides. Like everything else I think it’s super dependent on the individual.
 
All off of feelz?
No.
All off of feelz?
no not just off feels. I never had the acne problem until week 15 while on test and primo. Second cycle was test primo and anavar. Same thing happened on week 15 so I’ll just hop off primo and everything is back to normal. Since I switched to this new test the I noticed the acne came back. So I’m trying to dial in on that and make sure my estrodial is on point as I’ve read that the acne could be cause of low or high eatrodial. What are your thoughts on this ? And What advice you got? I get bloodwork done every 3 months
 
No.

no not just off feels. I never had the acne problem until week 15 while on test and primo. Second cycle was test primo and anavar. Same thing happened on week 15 so I’ll just hop off primo and everything is back to normal. Since I switched to this new test the I noticed the acne came back. So I’m trying to dial in on that and make sure my estrodial is on point as I’ve read that the acne could be cause of low or high eatrodial. What are your thoughts on this ? And What advice you got? I get bloodwork done every 3 months
Bloodwork was my advice for e2, but it sounds like you're already on that.
 
Exactly, I was on 720mg test/600mg mast e. I know mast doesn't lower serum levels but I actually have bloodwork proof that shit tanked my e2. E2 was at 25pg after taking out HCG.
Do you also have bloodwork showing your e2 without mast on a similar dose of test? I want to win an old argument I was having with someone lmao
 
Do you also have bloodwork showing your e2 without mast on a similar dose of test? I want to win an old argument I was having with someone lmao
Something even better imo. I have two blood tests, one with around 2400 TT and no masteron and had e2 over 100pg. another with 4000+ TT and with masteron and e2 was 49.8pg. I also have a test with more masteron being used and got my e2 even lower to 25pg. Although I didn't get a TT with my 25pg reading cuz I was going through insurance and couldn't get a lc/ms blood test for testosterone.
 
Something even better imo. I have two blood tests, one with around 2400 TT and no masteron and had e2 over 100pg. another with 4000+ TT and with masteron and e2 was 49.8pg. I also have a test with more masteron being used and got my e2 even lower to 25pg. Although I didn't get a TT with my 25pg reading cuz I was going through insurance and couldn't get a lc/ms blood test for testosterone.
Lemme see it. I can’t wait for the satisfaction of winning an argument that I will get nothing out of and which I’m sure the other party has already forgotten about. It’s gonna feel so good.
 
first one is high e2 without mast.
second one with stable test and mast doses:
  • Testosterone at 143.8 nmol/L = ~4148 ng/dL
  • Estradiol at 183 pmol/L = ~49.8 pg/mL
third test with same test but higher mast:

Btw I don't use an AI or any other compounds except for tren. However on these 3 blood tests, my tren ace wasn't being used. All tests were performed on Monday pre injection. I do 3 injections per week split Sat/Mon/Wed.
 

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first one is high e2 without mast.
second one with stable test and mast doses:
  • Testosterone at 143.8 nmol/L = ~4148 ng/dL
  • Estradiol at 183 pmol/L = ~49.8 pg/mL
third test with same test but higher mast:

Btw I don't use an AI or any other compounds except for tren. However on these 3 blood tests, my tren ace wasn't being used. All tests were performed on Monday pre injection. I do 3 injections per week split Sat/Mon/Wed.
Mind sharing what the test / mast dosages were for that last one where the E2 was within range?
 
Mind sharing what the test / mast dosages were for that last one where the E2 was within range?
First test: I think around 400-450mg test p
Second test: 720 test e/480mast p (equivalent to 575 mast e) but also using HCG 250iu 3x/weel
Third test: 750 mg test e/600mg mast e, but no HCG

I believe my E2 dropped due to the removal of hcg. but my mast e increasing as my test e increased as well. Ratios were very similar.

But I also believe it is highly individual, some can run 1g test/1g mast/700mg eq and be perfect with e2 not tanked. But many claim e2 can't crash serum e2 but sadly I'm living proof. I would rly love to use more mast but it would tank my e2.
 
First test: I think around 400-450mg test p
Second test: 720 test e/480mast p (equivalent to 575 mast e) but also using HCG 250iu 3x/weel
Third test: 750 mg test e/600mg mast e, but no HCG

I believe my E2 dropped due to the removal of hcg. but my mast e increasing as my test e increased as well. Ratios were very similar.

But I also believe it is highly individual, some can run 1g test/1g mast/700mg eq and be perfect with e2 not tanked. But many claim e2 can't crash serum e2 but sadly I'm living proof. I would rly love to use more mast but it would tank my e2.
I lowered me Mast to 400mg, and slightly increased my test, curious to see my e2. Testing in 2-3 weeks.
 
I lowered me Mast to 400mg, and slightly increased my test, curious to see my e2. Testing in 2-3 weeks.
So it seems that for you the Mast actually lowers your serum E2 levels. I know this is variable, as others have labs to show that Mast did nothing for their serum E2 (but did alleviate the side effects of high E2)
 
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