MESO-Rx Sponsor PCT 24X7 "1 stop shop for all day healthcare"

[nanika]

I know I'm asking for too much, but what's the Suzetrigine situation? It looks to be Vicodin without addiction risk - surely there must already be generics? Or too much legal risk

 

[sionnach]

Suzetrigine ...looks to be Vicodin without addiction risk

 

[BP_6]

I know I'm asking for too much, but what's the Suzetrigine situation? It looks to be Vicodin without addiction risk - surely there must already be generics? Or too much legal risk

It is very expensive. Don't know of any generics anywhere yet. Very new still and from the anecdotes I have heard, while it works on a whole new pathway it is not as good as the opiate based pain killers unfortunately.

 

[AllbrandNew]

2/3 landed for me. #3 is stuck in limbo/customs or something. No updates since 10/9. Hoping it's just a bit slower and not snagged lol.

3/3 started moving again, which is great. Didn't expect it to update again but pleasantly surprised.

 

[malfeasance]

Why is shipping back to normal? What changed?

 

[thecmorgan]

Why is shipping back to normal? What changed?

India post to usa resumed shipping

 

[PCT24X7 PHARMACY]

Hi everyone

We wish everyone a very Happy Diwali , may god bless everyone with a healthy , prosperous and joyful life ,


PCT24X7

 

[bananafeet]

Anyone got an idea about how much cilnidipine would be roughly equal to 40mg telmisartan?

I'm thinking about running it for a bit. Currently on 40mg telmisartan, 50mg metoprolol and 5mg Cialis and my BP is good.

 

[bigdaddyandfriends]

I’d suggest dropping the metoprolol and replacing it with 10mg cilnidipine, keeping the telmisartan and cialis.

 

[bananafeet]

I’d suggest dropping the metoprolol and replacing it with 10mg cilnidipine, keeping the telmisartan and cialis.

I need a betablocker for rate control. I could try nebivolol

 

[Apopkared]

I need a betablocker for rate control. I could try nebivolol

I was started on metoprolol a couples years ago for BP and rate control . Hated that medication because of the side effects . Lethargic an hour after taking and issues with ED . Start Nebivolol a couple months ago and holy crap it’s like night and day . No more lethargy and since it works on increasing N.O have had great pumps at the gym and morning wood again . Highly recommended!!!

 

[Photon]

I know I'm asking for too much, but what's the Suzetrigine situation? It looks to be Vicodin without addiction risk - surely there must already be generics? Or too much legal risk

It just got approved.
The patent is until 2040.
You wont see any generics for a long time..You can probably get raws from China tho.

 

[malfeasance]

I was started on metoprolol . . . the side effects . Lethargic an hour after taking and issues with ED

I do not experience either of these.

 

[Ghoul]

Anyone got an idea about how much cilnidipine would be roughly equal to 40mg telmisartan?

I'm thinking about running it for a bit. Currently on 40mg telmisartan, 50mg metoprolol and 5mg Cialis and my BP is good.

Telm confers unique benefits you don't want to lose. It's best in combination with Ciln.

What's your current BP with Telm 40?

 

[bananafeet]

Telm confers unique benefits you don't want to lose. It's best in combination with Ciln.

What's your current BP with Telm 40?

I thought clin was superior? BP hovers around 115-65 to 125-75

Used to be mid 130s

 

[Ghoul]

I thought clin was superior? BP hovers around 115-65 to 125-75

Used to be mid 130s

It's the best in its class, calcium channel blockers. For blood pressure control, an ACE/ARB class med is almost always used first, and then a med from another class is added to improve BP control via a different mechanism.

Think of your circulatory system as different sized pipes, from very large arteries to microscopic capillaries. They're different organs, essentially.

ACE / ARBs like Telm primarily relax small arteries,Tension in those arteries is a major source of high blood pressure.

Calcium channel blockers primarily relax large conduit arteries, further reducing blood pressure.

Also, normally when BP drops adrenaline is reflexively released to increase heart rate and constrict blood vessels to try and force blood pressure back up. Ciln blocks the release of adrenaline blunting this effect. This is also why Ciln is uniquely effective at stopping blood pressure from rising during anger, frustration or psychological stress.

Even though you are more or less in normal BP range, Ciln is one of the gentlest BP meds, and doesn't typically lower BP to the point of going too low. It sits there and jumps into action when BP rises, stopping it from going up too much.

It also provides many organ specific protective effects, for the kidney, heart, brain.

So you could add 10mg, just be on the lookout initially for low bp sides in case you're an atypical responder. Check your BP daily for the first couple of weeks, and after that it should be fine. You could start with half (5mg) tabs to be extra cautious, but it's a very safe addition (unlike other "hard" bp lowering drugs).

 

[bananafeet]

It's the best in its class, calcium channel blockers. For blood pressure control, and ACE/ARB is always used first, and then a med from another class is added to improve BP control via a different mechanism.

Think of your circulatory system as different sized pipes, from very large arteries to microscopic capillaries. They're different organs, essentially.

ARBs like Telm primarily relax small arteries,Tension in those arteries is a major source of high blood pressure.

Calcium channel blockers primarily relax large conduit arteries, further reducing blood pressure.

Also, normally when BP drops adrenaline is reflexively released to increase heart rate and constrict blood vessels to try and force blood pressure back up. Ciln blocks the release of adrenaline blunting this effect. This is also why Ciln is uniquely effective at stopping blood pressure from rising during anger, frustration or psychological stress.

Even though you are more or less in normal BP range, Ciln is one of the gentlest BP meds, and doesn't typically lower BP to the point of going too low. It sits there and jumps into action when. BP rises, stopping it from going up too much.

It also provides many organ specific protective effects, for the kidney, heart, brain.

So you could add 10mg, just be on the lookout initially for low bp sides in case your an atypical responder. Check your BP daily for the first couple of weeks, and after that it should be fine. You could start with half (5mg) tabs to be extra cautious, but it's a very safe addition (unlike other "hard" bp lowering drugs).

Cheers Ghoul. Excellent write up.

 

[malfeasance]

If I were currently telm 80 and metoprolol 50

Would I add ciln as a third med or replace one or the other?

 

[Photon]

If I were currently telm 80 and metoprolol 50

Would I add ciln or replace one or the other?

What's your BP?
That's the main question lol

 

[Ghoul]

If I were currently telm 80 and metoprolol 50

Would I add ciln or replace one or the other?

You would not replace an ARB or Beta Blocker with the CCB.

What's your current BP?

If you're borderline low (get dizzy when standing too fast; for instance), you'd lower Telm to 40.). Most of the time though, you could add 10mg Ciln without issue.

After being in Telm 80 / Ciln 10, I lowered Telm to 40 so I could increase Ciln to 20, since I really felt good on it. Like a non sedating physical anti-anxiety med. Tension in my back just disappeared after a few weeks at 20.