combing sema and reta

[syuri]

would it be suggested to incorporate both sema + reta at low-mod. dosages of each to reap GIP + Glucagon benefits from reta along with appetite suppression from sema?

on 8mg reta currently, and was curious about doing .25mg (or any amount) sema combined with 2-4mg reta for best of both worlds. i’m still ravenous off high reta doses and appetite is an issue. i want to feel satiated and hell, possibly even avoidant of food, because i always end up overeating. sticking to meal plans was always easy for me, even when initially starting reta and dealing with major suppression. i just ate less and didn’t have a single thought about another bite or a snack in-between.

i’m currently 190 lbs looking to drop 10-12lbs more.

reasons why:
-on my current reta dose and higher dosages, im still able to outeat my damn deficit.
-haven’t been able to sleep on my current reta dose. cortisol is sky high presumably due to RHR increase and glucagon, even with diet breaks.
-slept wonky on tirz aswell.
-reta at high doses (10-12) isn’t the best cost wise long term, and i have a script for ozempic anyways so sema is basically on hand and dirt cheap for me.
-Reta hasn’t given me that true app. suppression. i enjoy the glucagon benefits and also love the 9x stronger GIP factor on it compared to tirz. stacking it with tirz seemed pointless to me

any advice from people who’ve experimented with stacked GLPs is appreciated. thank you.

 

[quarter]

What else are you on

 

[syuri]

What else are you on

250 test rn cruising. looking to come down to 10% bf while incorporating anavar later on. appetite has been what’s been stopping me from progressing personally

 

[Unclejuice]

Might be more beneficial to add cagri for appetite suppression with retatrutide.

 

[syuri]

Might be more beneficial to add cagri for appetite suppression with retatrutide.

cagri made me fall asleep behind the wheel at 0.25mg. i can’t tolerate it, should’ve included that in my post. severe tiredness from it.

 

[Unclejuice]

cagri made me fall asleep behind the wheel at 0.25mg. i can’t tolerate it, should’ve included that in my post. severe tiredness from it.

Wow that's wild, I have read posts on other forums and Reddit of ppl running sema and Reta together. I havent myself but seems to work for others.

 

[Ghoul]

If you have a Sema prescription you should be able to get Tirz.

As long as you have coverage, it’ll be cheap, very good appetite suppression, and GIP benefits. A much better way to go imo.

Reta is very hit or miss for weight loss and serves a niche purpose for bodybuilders. Tirz is excellent for weight loss but not nearly as brutal as Sema.

 

[syuri]

If you have a Sema prescription you should be able to get Tirz.

As long as you have coverage, it’ll be cheap, very good appetite suppression, and GIP benefits. A much better way to go imo.

Reta is very hit or miss for weight loss and serves a niche purpose for bodybuilders. Tirz is excellent for weight loss but not nearly as brutal as Sema.

i’ve tried bargaining for tirz but my insurance won’t cover it oddly enough. i was interested in swapping to tirz beforehand aswell, getting my hands on it wouldn’t be hard, but i do enjoy the glucagon and metabolic benefits of retatrutide, so much so that i’d keep the glucagon (ALBEIT at a lower dose) even if it’s affecting my cortisol and sleep. it’s helped my weight loss in the past, however now it’s stunted.

i’ve noticed better post meal blood sugar readings from reta, and it’s 9x GIP affinity is what keeps me on it compared to tirz.

and with sema on hand, that’s why i asked for advice on combining; just for appetite suppression.

i will have to try tirz in the future though.

edit: forgot to mention reta has GREATLY helped my lipids, that’s all why i prefer sticking to it

 

[syuri]

Wow that's wild, I have read posts on other forums and Reddit of ppl running sema and Reta together. I havent myself but seems to work for others.

i appreciate the cagri suggestion nonetheless, definitely have to read up on reddit then. thank you!

 

[Ghoul]

i appreciate the cagri suggestion nonetheless, definitely have to read up on reddit then. thank you!

Well, the pricing makes it sting (it’s going down all the time though), but the safest route is increasing the Reta dose if you can swing it.

 

[HotPepper]

I just want to add that I have the same problem. Even on 15mg (even tried 18mg) Reta the appetite suppression ist very low.

I have combined Tirza and Sema in the past and at least during these three months, I did not notice any side effects.

I think if cagri won't work for me I will also go for a small dosage of Sema and Reta.

 

[syuri]

I just want to add that I have the same problem. Even on 15mg (even tried 18mg) Reta the appetite suppression ist very low.

I have combined Tirza and Sema in the past and at least during these three months, I did not notice any side effects.

I think if cagri won't work for me I will also go for a small dosage of Sema and Reta.

how much were your doses combining sema and tirz? did you grow accustomed to your dose or have a maintenance dose at all?

additionally, if cagri doesn’t work out, what glp would you add and at what dose?

sorry to slam you with back to back questions. i appreciate your insight!

 

[HotPepper]

1mg Sema and 3mg Tirza. Sema totally kill my appetite.

The first time I took Sema - the dosage was 0,5mg at 110 Kilo - was quiet hard because I wasn't able to drink more than 1,5 liters water per day (normaly I drink between 5-7 liters).
So If you never tried Sema really try as less as possible.

If cagri doesn't work I will try sema. I will reduce Reta to 10mg and I will try as less sema as possible, so I will start with 0,25mg sema.

 

[syuri]

1mg Sema and 3mg Tirza. Sema totally kill my appetite.

The first time I took Sema - the dosage was 0,5mg at 110 Kilo - was quiet hard because I wasn't able to drink more than 1,5 liters water per day (normaly I drink between 5-7 liters).
So If you never tried Sema really try as less as possible.

If cagri doesn't work I will try sema. I will reduce Reta to 10mg and I will try as less sema as possible, so I will start with 0,25mg sema.

love to hear your anecdote. hope all goes well and cagri is your key!

 

[juicebro]

cagri made me fall asleep behind the wheel at 0.25mg. i can’t tolerate it, should’ve included that in my post. severe tiredness from it.

I had a similar experience. I was just in bed most of the day. Awful but effective as far as appetite suppression goes.

 

[HotPepper]

As more expierence I got as more I'm advised not to buy it, because it's also pretty expensive

 

[syuri]

I had a similar experience. I was just in bed most of the day. Awful but effective as far as appetite suppression goes.

yeah. cagri really tires a ton of people out.

id rather rely on stimulants for suppression than cagri at this point

 

[Anonymous35]

From my personal experience taking reta ED cause more appetite reduction than one or 2 times / w

 

[syuri]

From my personal experience taking reta ED cause more appetite reduction than one or 2 times / w

i’ve tried tampering out with my dosing, but to no avail unfortunately. i simply dont experience the same initial suppression or hunger reduction i had when i started
(albeit i started a year ago, lost 30lbs on it and started TRT 6 months in all within the span…)

 

[HotPepper]

I just started with sema today lol

The quick change was happening because I nearly shit in my pants again. As I have already written in the big thread I often have flushes to go the toilette instantly. If I'm not able to arrive the toilette in a minute I (nearly) piss or shit in my pants. Never had that before reta.

I started with 0,2mg sema because I just have taken reta just two days ago (I pined reta twice a week)