white-boyka
New Member
does it look smaller/thinner?
MESO-Rx
Anabolic Steroids
Accutane permanent cure?
- Thread starter Ghoul
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Ghoul
Member
Those sebaceous filaments coming out of my nose was the weirdest, but most satisfying part of the entire process. My nose visibly shrunk, those pores hadn’t been that clean, ever, and ultimately the pores shrunk to the point of disappearing. It was unexpected and the visual improvement was dramatic.
For anyone who doesn’t know what this is, imagine thousands of black and white heads being pushed out from behind, emerging as strands, making your nose look like it’s covered in hair. It’s caused by the sebaceous (oil) glands shrinking, making the entire pore tighten down, squeezing out all the contents (they emerge as dry filaments, not an oily mess). It’s incredible.
AAS makes those glands grow larger, so most of us have enlarged pores above and beyond what DHT normally does to enlarge them. When they shrink, skin looks much smoother and significantly younger.
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white-boyka
New Member
is that specifically due to dht? or test alone (test + dut) can cause that also?
Ghoul
Member
Looking forward to this. Hopefully it can shrink down my giant shnozer lol. Got some accufine on the way.
How long did it take for this to start happening?
Ghoul
Member
I think it was around 2 months, about 100mg ( 50mg 2x / day).
Probably dose dependent. If you are running 180mg per day, it'll happen within the first month i would assume. But low doses like 10 or 20mg would take much longer
Thank you very much for this thread, Ghoul. I'll be starting Accufine next week. I am 52 and tired of dealing with my super oily skin and the damn zits that still can randomly appear anywhere (even on my ear lobes or inside my ears and nose entrance). I want to do the "max" protocol and be done dealing with this shit once and for all. I am 225 pounds.
1. What should my starting daily dose be?
2. How often should I increase my dose and by how much?
3. What maximum daily dose should I try to get to?
4. Is 23,000 mg the grand total I need to get to in the end (length of time to get there doesn't matter, right?)?
My goal is to push this to the max, get it over with as quickly as possible, and achieve the most optimal long-term results.
1. What should my starting daily dose be?
2. How often should I increase my dose and by how much?
3. What maximum daily dose should I try to get to?
4. Is 23,000 mg the grand total I need to get to in the end (length of time to get there doesn't matter, right?)?
My goal is to push this to the max, get it over with as quickly as possible, and achieve the most optimal long-term results.
Ghoul
Member
Very similar to me, worth every stick of lip balm and back ache. Only regret was waiting as long as I had.
I was extremely cautious (hence why my journey started as “low dose” then once I realized fears were exaggerated, scrambled to buy more to shift to “high dose” as evidence proves that most effective, and safe). I did want to “get it over with as fast as possible”, it’s not the most pleasant experience, but as the comment above, you get “addicted to the progress”.
I started 10mg / 1x day after eating something with fat (breakfast). 5 days.
Then 10mg / 2x day (20mg/day) 5 days (Not as concerned with fat for second dose, but having with meal is helpful, so time of second dose varied to align with meal.
Then 20mg morning 10mg evening (30mg/day) 5 days
Then 20mg / 2x day (40mg/day) 5 days
Then 30mg / 2x day 5 says
40x2 , 50x2 , 60x2 etc every 5 days.
If sides were rough, I might not increase until 6 or 7, 10 days at the most.
Once I got to around 180mg / day sides did not ease off, and I started climbing back down (far easier then the climb up). I decided an extra 2-3 weeks to reach the cumulative total was worth the relief of sides I had enough of by that point.
Going down, even at high doses like 140mg day had virtually no sides.
So it’s essentially waiting for sides to ease, then increasing when they do, then repeat. As I said, for me, 5 days things would ease off. (2nd day after higher dose was worst).
It’s all up to you and what you can tolerate.
MAX DOSE should not exceed 2mg / kg, though you don’t have to go that high, it’ll speed things up if you can, bringing discomfort to an end sooner.
Yes, 23,000 is enough. Try to make 50% the 40mg dose, 25% 30mg, then the rest split 10/20 for cost effectiveness and dosing flexibility (large doses are cheaper per mg.).
Length of time (within reason) isn’t a crucial factor, but I’m glad I pushed as hard as I could to get it over with. Recovery takes about a month (ie lips / eye dryness returning to normal).
Avoid excess sun, you can burn easily, and skin will be fragile(thinner) temporarily, nothing very abrasive. Careful with adhesives like bandaids).
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Did you get labs done regularly to monitor LDL/HDL, ALT/AST, etc.?
I'm guessing you avoided using any hepatotoxic compounds during your course of the accufine?
Ghoul
Member
I had a baseline test, coincidentally a routine blood panel a month before starting.
Everything was normal and I didn’t test again until 2 months after finishing (everything was normal).
I completely avoided alcohol, I don’t use oral AAS, and have no history of liver issues.
From a number of studies, it seems the previous regime of monthly testing is unnecessary, creates “needless stress” from elevated but transient and clinically insignificant elevations, and when problems were found in a tiny minority, alcohol almost always plays a role.
At one end of the “new Accutane protocol” spectrum some derms only check baselines before starting, and if no indicator of liver issues, it’s not checked again unless there’s some sign of a problem. The risk of an issue of anyone without a preexisting issue, avoids alcohol (and any known hepatoxic compound like oral AAS) seems infinitissimaly small.
The most common “happy medium” is baseline and again around two months in.
But of course I’m no doctor. It’s your body and risk tolerance. If this seems unwise to
you for any reason, better to err on the side of caution. It’s helpful to understand what represents an acceptable “abnormal marker” and what indicates a problem that would warrant stopping treatment.
IMO if you know you can’t avoid drinking while doing this, I wouldn’t even start. Same for orals or any hepatoxic compound. If you’re using herbal supplements, better check to see if they’re hepatoxic. Some are bad enough they’re banned in certain places (red yeast rice for instance). As far as I’m aware, the only, and still extremely rare, accutane induced liver injury cases in otherwise healthy people were caused by alcohol use.
Thanks a lot, I really appreciate your contribution on this. I look forward to having clear skin.
Ghoul
Member
I mean that’s me.
Do plenty of people still drink in moderation without issue? Given the extremely low rate of liver injury, I’m certain that’s a yes.
Do some derms prescribe Doxycycline, a potentially brain swelling / blindness inducing interaction requiring a multi week washout period between stopping the antibiotic and starting accutane? Yep, to my shock, with no damaging incidents reported in the literature. (I didn’t wait a full 2 weeks, just 1, and every slight headache for the first couple of weeks had me wondering if my brain was a goner…)
I came into this terrified of everything the Accutane mythology had to offer. Nothing but permanently dry lips, sandpaper eyes, IBS, and a liver transplant in my future, and it all worked out for me, and apparently, for 99.999% of everyone else too.
The primary risk seems to be once you start down this road, you’re committed, whether it’s mildly unpleasant or a world of suck, for months, or you quit and suffered for nothing.
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