How bad is my kidney function? Ok to continue cycle?

[explodingHeart]

Ghouls apprentice here:
"There are two types of statins either lipophilic like atorvastatin and simvastatin or hydrophilic like rosuvastatin.24 Hydrophilic statins are less cross‐plasma membrane so they have less pleiotropic effects compared to lipophilic statins.24 Of note, statins are also classified according to their nature, either natural like simvastatin and lovastatin, or synthetic like rosuvastatin.24 Natural and synthetic statins have different pharmacokinetic properties but they have similar lipid‐lowering effects. Remarkably, statins lead to a dose‐dependent effect in reducing cholesterol and LDL.25"

Source: Pros and cons for statins use and risk of Parkinson's disease: An updated perspective - PMC

Newever statins don't generally cross the blood brain barrier, and have been shown to reduce Parkinson's Disease by lowering inflammation.

Conclusion of above study:
"PD is the second most common NBD consequent to AD. Statins are the most common lipid‐lowering agents used in the management of dyslipidemia and the prevention of primary and secondary CVD events. Statins are not used in the management of PD, but they are frequently used in the cardiovascular disorders commonly associated with PD in the elderly population. Therefore, the use of statins in that population may affect PD outcomes. Statins have many pleiotropic effects like antioxidant and anti‐inflammatory effects. The possible effects of statins on PD neuropathology are conflicting either protective or harmful on PD neuropathology. As well, there is a controversial point regarding the role of serum lipids in the pathogenesis of PD. In this bargain, as statins reduce serum cholesterol, they may affect the PD neuropathology in bidirectional ways either protective or harmful. The protective role of statins against PD risk is through modulation of inflammatory, lysosomal signaling pathways, and microglia activation. However, long‐term statins therapy for primary or secondary prevention of CVDs may increase PD risk by different mechanisms including reduction of CoQ10. Taken together, according to the recent and updated studies, controversial points still present regarding the short‐ and long‐term effects of statins on PD neuropathology. Therefore, large‐scale prospective and retrospective studies are warranted in this regard to confirm the mechanistic role of statins in PD neuropathology."

MESO-Rx Sponsor Post in thread 'PCT 24X7 "1 stop shop for all day healthcare"'

Dec 12, 2025

Oh, I thought Repatha was a statin.

What statins do you suggest I look into? Any better than the others?

As someone in the misfortunate 1% who had side effects from older statins, Pitavastatin, the latest generation of statin that only recently went from $500/mo to a cheap generic, is the one I recommend. It was formerly limited to people who desperately needed a statin but had side effects on others. It takes the already low risk of sides from modern statins and drops it even lower.

The minuscule doses compared to others hint at how tightly focused it is. That said. most...

• Ghoul

• 
• 

Any idea what happened to Ghoul?

 

[SmallTitsIRL]

Any idea what happened to Ghoul?

His LDL was so good, doctor's took him to a research center

 

[explodingHeart]

His LDL was so good, doctor's took him to a research center

His skin was so youthful and rejuvenated from accutane, making him look 21 years old that he got held up as passport control because they thought he was using a stolen passport.

 

[initialize]

Just did a UACR today. Pray for me that it goes well lol

 

[Photon]

Any idea what happened to Ghoul?

Looks like he abandoned us with all these new joiners..

 

[bananafeet]

Looks like he abandoned us with all these new joiners..

Someone ask him how much HGH he has stashed and he is still counting.....

 

[explodingHeart]

Just did a UACR today. Pray for me that it goes well lol

But even if this can be fudged can it not?

If I took a high volume workout to failure, and tested 24-48 hours, my kidneys will still looked fucked for days.

You'd need like four days off training and probably a few weeks of real TRT test levels and no GH to get accurate readings.

 

[bananafeet]

But even if this can be fudged can it not?

If I took a high volume workout to failure, and tested 24-48 hours, my kidneys will still looked fucked for days.

You'd need like four days off training and probably a few weeks of real TRT test levels and no GH to get accurate readings.

No. It is a ratio to creatinine and albumin in the urine. If it's elevated it means you're leaking protien into the urine and have degeneration of the kidney .

Maybe the kidney could be stressed or irritated but from what I've read cystatin C + creatinine + urine ACR is bulletproof. You plug it into the calculator I posted.

I had trace protien in my urine but very low urine ACR.

 

[explodingHeart]

No. It is a ratio to creatinine and albumin in the urine. If it's elevated it means you're leaking protien into the urine and have degeneration of the kidney .

Maybe the kidney could be stressed or irritated but from what I've read cystatin C + creatinine + urine ACR is bulletproof. You plug it into the calculator I posted.

I had trace protien in my urine but very low urine ACR.

Rhabdo can spike UACR. A tough workout, mangling your leg in an accident, etc.

Physical Activity and Albuminuria - PMC

Higher urinary albumin excretion predicts future cardiovascular disease, hypertension, and chronic kidney disease. Physical activity improves endothelial function so activity may reduce albuminuria. Among diabetics, physical activity decreases ...

pmc.ncbi.nlm.nih.gov

> Transient proteinuria, including albuminuria, is common after intense exercise, and the prevalence ranges from 18% to 100%, depending on the type and intensity of the exercise (13, 14).

 

[bananafeet]

Rhabdo can spike UACR. A tough workout, mangling your leg in an accident, etc.

Physical Activity and Albuminuria - PMC

Higher urinary albumin excretion predicts future cardiovascular disease, hypertension, and chronic kidney disease. Physical activity improves endothelial function so activity may reduce albuminuria. Among diabetics, physical activity decreases ...

pmc.ncbi.nlm.nih.gov

> Transient proteinuria, including albuminuria, is common after intense exercise, and the prevalence ranges from 18% to 100%, depending on the type and intensity of the exercise (13, 14).

Guess I was wrong!

Good to know. When I did my test I wasn't training or eating massive amounts of protien.