AlexDavis43
Member
Absolutely. I did re check once I switched over to injectable test and the DHT / E2 proportions were essentially the same. A little more E2 but still much more skewed towards DHT
I am guessing there is a lot of variation between individuals, but topical test will preferentially be metabolized to DHT due to the high expression of 5 alpha-reductase in the skin. The test needs to pass that metabolic “gauntlet” before getting into the circulation.
the study on topical test preferentially converting to DHT was on scrotal application
very different between dudes using Androgel on their shaved pecs vs those who put it on their shaved balls

