My interest in the psychological effects of anabolic steroids...

[Millard]

I've always been interested in the psychological and behavioral effects of anabolic steroids. The very first article that MESO-Rx paid for publication rights was for a journal review article on the topic by Yesalis, Bahrke, and Wright. There have been many original MESO-Rx articles on the topic published since then, but this was how it all started at MESO...

It's a bit dated now but it was a comprehensive review at the time.

Psychological and Behavioural Effects of Endogenous Testosterone Levels and Anabolic-Androgenic Steroids Among Males: A Review

Summary The psychological and behavioural effects of endogenous testosterone levels and anabolic-androgenic steroids in males have been investigated for

thinksteroids.com

 

[Eman]

"Joslyn (1973) has reported that injecting 3 infant female rhesus monkeys with 2mg of testosterone propionate intramuscularly 3 times per week over 8 months increased their aggressive behaviour so much so that they replaced males in top positions of the social hierarchy. Since this behaviour persisted for a year after the last hormone injection, the author suggests either that the male hormone may have directly induced a permanent change in the nervous system or alternatively that the socially dominant behaviour was so well learned during hormone treatment that it became independent of hormonal support."

That is fascinating.

 

[Type-IIx]

T seems to increase aggression by reduced activation of the orbitofrontal cortex, the neural circuitry of impulse control and self-regulation. But note that the effect size of T on a model of social aggression in humans is very small (r=0.35; barely significant). Higher testosterone in humans is related to aggression, social dominance, and hyperreactivity to status threats in both men and women. I have remarked before that I have a strong supposition that this is at the root of the romantic paranoia that users of tren often report (being "cucked" is the ultimate status threat).

 

[Type-IIx]

The Hannan et al. (1988) findings are very interesting for explaining some of the widespread anecdotal reports of particular psychological effects with nandrolone.

 

[Iamnatty]

The Hannan et al. (1988) findings are very interesting for explaining some of the widespread anecdotal reports of particular psychological effects with nandrolone.

Where do you find this information at.

 

[Mac11wildcat]

What interests me is the varied psychological effects we see. Whether it’s just a variation of the original disposition of the user, the age at onset of use, or sensitivity to individual drugs themselves. Tren is the ‘obvious’ one, but EQ is getting quite a reputation for inducing anxiety.

 

[Millard]

"Joslyn (1973) has reported that injecting 3 infant female rhesus monkeys with 2mg of testosterone propionate intramuscularly 3 times per week over 8 months increased their aggressive behaviour so much so that they replaced males in top positions of the social hierarchy. Since this behaviour persisted for a year after the last hormone injection, the author suggests either that the male hormone may have directly induced a permanent change in the nervous system or alternatively that the socially dominant behaviour was so well learned during hormone treatment that it became independent of hormonal support."

That is fascinating.

Yeah, the idea that permanent changes occur with limited AAS use is very interesting but also that researchers allowed for the possibility that the learned behavior is what changed the nervous system in the long-term.

I remember as a undergrad RA, my mentor was really excited by research showing that CBT could induce brain changes similar to that seen with meds.

I can totally see learned behavior (e.g. social/sexual confidence, etc) while on AAS persisting long after discontinuation in many users.

 

[Millard]

Where do you find this information at.

It's in part 2 of the above article discussing ways AAS could affect the CNS.

 

[Cherokee]

Cognitive Deficits in Long-Term Anabolic-Androgenic Steroid Users

Millions of individuals worldwide have used anabolic-androgenic steroids (AAS) to gain muscle or improve athletic performance. Recently, in vitro investigations have suggested that supraphysiologic AAS doses cause apoptosis of neuronal cells. These findings ...

www.ncbi.nlm.nih.gov

preliminary findings raise the ominous possibility that long-term high-dose AAS exposure may cause cognitive deficits, notably in visuospatial memory.

Visuospatial function refers to cognitive processes necessary to "identify, integrate, and analyze space and visual form, details, structure and spatial relations" in more than one dimension.[1]

Visuospatial skills are needed for movement, depth and distance perception, and spatial navigation.[1] Impaired visuospatial skills can result in, for example, poor driving ability because distances are not judged correctly or difficulty navigating in space such as bumping into things.[1]

 

[Eman]

I can totally see learned behavior (e.g. social/sexual confidence, etc) while on AAS persisting long after discontinuation in many users.

Same. I think that's what really intrigues me by that paragraph... I mean, which is it?

I have wondered about this before. Many times in fact. I've always described it as "primal switches in the brain getting flipped". I have come to a passive conclusion that the switches get flipped on but they never actually get flipped back off even when the stimulus is gone.

Very cool collection of articles, I've never come across them before and I'm not familiar with any of those authors either. Really enjoy these older articles getting bumped!

 

[Jin23]

I've always been interested in the psychological and behavioral effects of anabolic steroids. The very first article that MESO-Rx paid for publication rights was for a journal review article on the topic by Yesalis, Bahrke, and Wright. There have been many original MESO-Rx articles on the topic published since then, but this was how it all started at MESO...

It's a bit dated now but it was a comprehensive review at the time.

Psychological and Behavioural Effects of Endogenous Testosterone Levels and Anabolic-Androgenic Steroids Among Males: A Review

Summary The psychological and behavioural effects of endogenous testosterone levels and anabolic-androgenic steroids in males have been investigated for

thinksteroids.com

View attachment 159285

I had no idea meso had such roots. That's very nice to hear.

 

[Rido]

I have remarked before that I have a strong supposition that this is at the root of the romantic paranoia that users of tren often report (being "cucked" is the ultimate status threat).

UHH I gotta say. Tren is reminding me of nandrolone of me wanting to pound other women's pussy in and watch my wife have a train ran on her too...

 

[lukiss96]

What interests me is the varied psychological effects we see. Whether it’s just a variation of the original disposition of the user, the age at onset of use, or sensitivity to individual drugs themselves. Tren is the ‘obvious’ one, but EQ is getting quite a reputation for inducing anxiety.

What I notice is probably different from most people, I get aggressive on equipoise stacked with test and calm on testosterone solo at any dose up to 1g.

 

[T&H]

I've ran test, mast, primo, and a number of different orals at higher doses. Other than a few days of euphoria a few weeks into my first time using testosterone, I don't ever notice psychological changes when running AAS.

 

[Type-IIx]

UHH I gotta say. Tren is reminding me of nandrolone of me wanting to pound other women's pussy in and watch my wife have a train ran on her too...

Deviants are by definition deviations from the norm bro