MESO-Rx
Anabolic Steroids
Acne treatment
- Thread starter Deebo825
- Start date
Accutane at 20mgs per day until you accumulate a total dose consumed of 120mg/kg of body weight.
Ghoul
Member
An alternate method that permanently eliminates acne in about 65% of people is 10mg / day until acne is clear + 2 months.
Always take it with a high fat meal or up to 80% won't be absorbed.
NEVER use a tetracycline antibiotic while on Accutane, it can cause brain swelling in rare cases
Avoid the dry UGL tabs of isotretinoin. There's a reason pharma only makes it in a soybean suspension in gelcaps, and India pharma versions are just as cheap as UGLs.
Feel free to hit me up with any questions. I'm on this protocol now.
Always take it with a high fat meal or up to 80% won't be absorbed.
NEVER use a tetracycline antibiotic while on Accutane, it can cause brain swelling in rare cases
Avoid the dry UGL tabs of isotretinoin. There's a reason pharma only makes it in a soybean suspension in gelcaps, and India pharma versions are just as cheap as UGLs.
Feel free to hit me up with any questions. I'm on this protocol now.
twistedfire11
New Member
I was on accutane in high school prescribed by a dermatologist I was told not to take it with a high fat meal. I was on a starting dose of 20mg a day for the first month bloods drawn every month. After the first month it was prescribed based on weight of the patient. I was 80kg I got put on 40mg 2 times a day with meals.
Liter O' Test
Member
well is it the test or the primo or the estrogen from the test?
This is the question.. if your e2 is in range then it is test or primo.. if you have done test alone before without acne, then it is the primo.
in my experience usually chest and back is estrogen related but thats just a guess. Maybe you thought the primo would lower your estrogen enough to where you don't need A.I? and yet you do.
regardless, your first step is to get an estrogen sensitive LC/MS test.
if its in range, then you know its probably the primo
then remove the primo, this may increase your e2
then once the primo fades weeks later
get e2 checked once again
(somewhere around here dial back in estrogen with A.I)
then if your acne gets worse or doesnt improve with just test and e2 in range, then the acne is coming from DHT/your own genes
which means you'll have to do accutane and you can even take a little finasteride/dutasteride to knock down some DHT
i would not mess with high or medium dose accutane, seems like it takes 2-3 months for the accutane to clear you up anyway and if you do a high dose youll just get worse sides and it wont be faster. IMO
see how much of a pain in the ass the testing and dropping compounds is?
this is why people should just run test for years and figure out their own estrogen before they add in other compounds, especially ones that lower e2. youre looking at months and 2-3 blood tests and winging your A.I to figure this out properly
if thats all too much for you just drop the primo, go to a derm for antibiotics, wait a few weeeks, go back to your usual A.I
but you started TRT not long ego so i wouldnt be surprised if your e2 was already high or has been this whole time
This is the question.. if your e2 is in range then it is test or primo.. if you have done test alone before without acne, then it is the primo.
in my experience usually chest and back is estrogen related but thats just a guess. Maybe you thought the primo would lower your estrogen enough to where you don't need A.I? and yet you do.
regardless, your first step is to get an estrogen sensitive LC/MS test.
if its in range, then you know its probably the primo
then remove the primo, this may increase your e2
then once the primo fades weeks later
get e2 checked once again
(somewhere around here dial back in estrogen with A.I)
then if your acne gets worse or doesnt improve with just test and e2 in range, then the acne is coming from DHT/your own genes
which means you'll have to do accutane and you can even take a little finasteride/dutasteride to knock down some DHT
i would not mess with high or medium dose accutane, seems like it takes 2-3 months for the accutane to clear you up anyway and if you do a high dose youll just get worse sides and it wont be faster. IMO
see how much of a pain in the ass the testing and dropping compounds is?
this is why people should just run test for years and figure out their own estrogen before they add in other compounds, especially ones that lower e2. youre looking at months and 2-3 blood tests and winging your A.I to figure this out properly
if thats all too much for you just drop the primo, go to a derm for antibiotics, wait a few weeeks, go back to your usual A.I
but you started TRT not long ego so i wouldnt be surprised if your e2 was already high or has been this whole time
funkygiraffe
Member
I ended up ordering some, I get minor acne generally, always seem to have one or two zits. Planning on using 20mg a day, have you noticed any increases in acne while using it. I'm aware that there is an "expulsion phase" wherein acne becomes far more pronounced at typical dosages. Was this your experience at low dose?
My e2 was high after starting trt but I’ve had that In normal range for months now with arimadex. I started getting breakouts on just the test before I was running the primo, but The primo may have made it a little worse. I haven’t gotten labs yet to see if the primo has lowered my e2 anymore. I’m running 2:1 ratio test to primo. I’m just gonna get with a dermatologist and see about low dose accutane
Did you go to a dermatologist or just order from a source?
Justaguy99
Member
I started using a serum with salicylic acid
Cleared up in 2 weeks.
Cleared up in 2 weeks.
I’m leaning towards trying low dose accutane like this. Have you had any side effects from this?
That’s good to hear, I just started using a benzoyl peroxide soap and the salicylic gel.
funkygiraffe
Member
sourced from pct24x7 -- not to shill haha but they're leagues better than dashpct
didn't bother with derm because I have very mild acne.
Ghoul
Member
Very mild dry lips. There's something called "Accutane Purge", where acne seems to worsen for a time. With a low dose many don't get it at all. My bacne got progressively better over the first three weeks, then seemed to rebound a little, including some very tiny zits where I never had acne before, and after a couple of weeks everything seemed to massively improve and now I'm down to red marks where the pimples used to be.
A big problem with accutane is absorption. Do a google search and you'll confirm that taking it with a fatty meal has been the manufacturer's guidance from day one and continues to be, universally. Researchers speculate most failures result from people not taking it with meals. It's a drug that's difficult to absorb without fat to carry it.
In the last few years a couple of developments have come out to solve this issue. One is a type of isotretinoin called "absorica LD" They reduce the drug particles to nano sizes, making them far more absorbable and not reliant on fats. In fact so much more of it gets absorbed, the doses are lowered, which reduces the possibility of side effects even further.
IE:
10mg Isotretinoin equivalent is 8mg absorica.
20mg is 16mg
etc.
I assumed that version wasn't available as a generic, but it actually is. If I were starting over, I'd use this instead. It's not in the India pharma suppliers (like Pct24x7) catalogs, but most will take requests.
It's called Sotret NF from Sun Pharma.
Since the average of the low dose protocols is 4 months to clearance + 2 to 4 more months to allow enough skin turnover to reduce visible acne scars, and the fact you may want to increase to 10mg x 2 a day, still a very low dose with nearly no sides (normal dose for 200lbs is 90mg/day) you'll want at least 300 10mg gelcaps on hand. Personally I'd get 500 to keep my options open.
I use Accufine which has been Jano tested and been very effective for me but I take it with scrambled eggs and an ounce of cheese to ensure it's fully absorbed.
They come in 10 gelcap strips.
So 50 strips x $1.40 -15% sale is $59
Request a price quote for 50 strips of Sun Pharma Sotret NF 8mg. It shouldn't be more than approx an additional 85¢ per strip since the India retail is only 70 rupees more.
@PCT24X7.STORE
If he can get it and it's not too much more than the Accufine 10mg consider it so you won't have to be as concerned about a high fat meal and sides risk will be even lower.
For a laugh here's the retail price for 510 gelcaps of the brand name version in the US.
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Liter O' Test
Member
ratio doesnt mean anything at all and youre basically just injecting acne, since youre not getting big off of some trt primo lol, ffs
everybody is buying the primo hype for no reason at all
everybody is buying the primo hype for no reason at all
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Liter O' Test
Member
stop posting
I’m on more than a trt dose, but thanks for the input
Liter O' Test
Member
you never even included your doses or your estrogen level, why even take primo? its giving you acne, there is no sense in taking accutane to be able to use primo
Ghoul
Member
An accidentally high dose of this stuff would be a disaster. Low dose has proven very safe, but even the regular high dose protocol was a "last resort" because of the potentially awful side effects.
Definately don't use this with any tetracycline antibiotic, which can cause brain swelling.
That make females sign a pledge to not get pregnant while on this and for months after due to the birth defects it causes while in your system.
Anyone going this route should make sure they read the precautions out there. Low dose avoids these hazards for the most part, but still better to be safe.
Liter O' Test
Member
no everything injected acts exactly the same way even at the same dose /s
i swear something about injecting or reading about hormones makes midwits think they are scientists or smart or something
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