@TRT@40 would you say hcg gets your level to a certain point then plateaus? Then if you stop hcg would you say you maintain that level or would it fall? I cant justify the cost when I can self medicate with test for less.
Hi Btcowboy, I checked my records and below is the relevant data:
Baseline Test No. 1: Month 0
Test (Free) =196
LH=5
FSH=3
Test No. 2: Month 8
HCG=1000IU EOD for 8 months and nothing else (no AI or test)
Test (Free) =585
LH & FSH less than 1
IGF-1=349*
estradiol=327* (endo still did not prescribe AI. Had I been a member of this forum at this time, I would know how to manage e2 myself)
Test No. 3: Month 13
HCG=1000IU EOD for 13 months and nothing else (no AI or test)
Test (Free) =754
LH & FSH less than 1
estradiol=409*
At this point, to address elevated e2, I asked the endo to give me test injection Rx and lower the HCG dose to about 300IU eod.
BTW, because I wanted to keep my fertility chances, I started with HCG monotherapy.
Test No 2 and 3 show test levels seemed to continuously increase over time of 13months with 1000iu HCG EOD. I dont have data beyond 13 months with HCG only so I cant say for sure but I would think test level would plateau since leydig cell output would remain constant with fixed input. But I have read long term use of HCG can cause leydig cell desensitization but I dont have know of any studies showing this to be the case. if this is true, then over time test levels start to decline with a fixed amount of HCG due to desensitization.
In my case of secondary hypogonadism, stopping HCG would result in test dropping to baseline. I think someone with healthy HPTA would respond differently.