Arail Pharmaceuticals - US Domestic

I love the TNE pre workout, but I didn't account for it's impact on RBC and Hematocrit. Sadly have to pause it for a bit to get those in order. Was hoping to stock up on the new batch but I'll leave it for the rest of y'all.
Double red donations will help you out.
 
I do conventional donations which bring me back to the high 40s. That being said, I’m not particularly susceptible to blood thickening.
 
I've always been told to keep it at 2x a week max. Occasionally, like not more than once a month, 3 is okay but don't push it. The only science I have behind that is someone I don't remember told me, and I said okay.
 
Wow great, I wasn't aware of the double red. I'll remember that in the future. How long after you donate have you tested again to see the drop?
Donation is an over-recommended quick fix that can lead to more issues if done repeatedly, and is in most cases unnecessary in the first place. Just my opinion, I fully expect flames of disagreement. But if you are a regular donator I encourage you to do some digging here and elsewhere on downsides and alternatives.
Anywho, back to our regularly scheduled programming.

No Problem! It's been a very successful product and the fact that we can make it without super toxic ingredients is great.

The TNE is amazing and I'm glad you're doing it without guacamole. I hope others follow suit. Mine did arrive crashed, but it wasn't so bad the ol' coffee warmer or warm bath couldn't fix it. No pip, best pwo ever!
 
Donation is an over-recommended quick fix that can lead to more issues if done repeatedly, and is in most cases unnecessary in the first place. Just my opinion, I fully expect flames of disagreement. But if you are a regular donator I encourage you to do some digging here and elsewhere on downsides and alternatives.
Anywho, back to our regularly scheduled programming.



The TNE is amazing and I'm glad you're doing it without guacamole. I hope others follow suit. Mine did arrive crashed, but it wasn't so bad the ol' coffee warmer or warm bath couldn't fix it. No pip, best pwo ever!
For sure I have seen that warning. I don't hope to be a common donor, but where my numbers were it seemed like the best move.
 
For sure I have seen that warning. I don't hope to be a common donor, but where my numbers were it seemed like the best move.
I donate fairly often. The issue is that it doesn't fix anything permanently. It will drop your HCT and then in 8 - 12 weeks it'll be back where it's at. You must watch your Iron / Ferritin levels when donating. You can end up with iron deficiency which is a horrible existence. I've consulted with lots of coaches, doctors, etc. and the consensus seems to be that since it's a secondary erythrocytosis, donation is not necessary. Then again, if you're HCT is over 55, you may want to go ahead and donate.

The analogy many have mentioned are those living at altitude, who will have similarly high HCT levels. Endurance athletes who train with air-restricted masks on can also induce this same secondary erythrocytosis. They are not recommended to have phlebotomy / blood donation. Medically the confusion stems from the conflation of secondary erythrocytosis with the increased RBC / Hgb / HCT seen in blood disorders like Polycythemia Vera, where phlebotomy is required (because there is proliferation of all blood products, including platelets - which would cause clotting).

If you grab a physiology text book and study the mechanisms of clotting, you won't find any mention of "thick blood" from high Hgb / HCT (unless it is in the context of a blood disorder such as P Vera)
 
If you grab a physiology text book and study the mechanisms of clotting, you won't find any mention of "thick blood" from high Hgb / HCT (unless it is in the context of a blood disorder such as P Vera)
True, since clotting is not the primary, secondary, or tertiary concern with erythrocytosis.

What is the concern? One that should not be overlooked or hand waved away.
 
Agree with this as a physician. The hematocrit panic is extrapolated from patients with polycythemia vera (a type of blood cancer). Secondary erythrocytosis is similar to living/training at altitude and generally is not harmful. Many AAS (including test, bold, and primo) can raise Hg/Hct but very levels are often attributable to other factors like sleep apnea.

Thrombosis is much more linked with high platelet levels which is something totally different and not typically seen with Epo stimulation.

Occasional donation isn’t so harmful but it’s a short term fix and when done too often will result in depleted ferritin and associated problems.

Things to help control hematocrit without donation:

Silymarin (iron chelator)
Naringin (increases RBC degradation by spleen)

Rather than aspirin, for those who want to ‘thin’ their blood with less bleeding risk, Nattokinase 10,000-12,000fu/day is the best choice. It breaks down fibrin which is a main component of blood clots and also contributes to atherosclerosis. It’s kind of like a blood vessel Roto-Rooter and with well controlled limited should help prevent ASCVD associated with PED use.


Donation is an over-recommended quick fix that can lead to more issues if done repeatedly, and is in most cases unnecessary in the first place. Just my opinion, I fully expect flames of disagreement. But if you are a regular donator I encourage you to do some digging here and elsewhere on downsides and alternatives.
Anywho, back to our regularly scheduled programming.
 
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