Are DHT derivatives actually anti-estrogenic?

[I6JQdr06]

People seem to think that DHT derivatives are anti estrogenic but I’m not convinced this is the case. Am I right in saying that these are the compounds which are regularly reported to show estrogen-attenuating activity?

Boldenone
1-test (DHB)
Primobolan

Seems to me the common feature of these three compounds is the 1(2) double bond.

If my conjecture is correct, stenbolone and turinabol will also lower E2 levels. Does anyone have any anecdotal evidence of this being the case?

Does anyone have any anecdotal evidence of Masteron, anavar, or winstrol lowering their E2? This would support the DHT hypothesis.

Note: when I say “anecdotal evidence”, I mean supported by before and after blood work.

 

[Iron_Yuppie]

I’ve never seen anyone demonstrate that masteron actually lowers serum e2. I’ve also not really seen anyone explicitly say that it does, so that’s somewhat moot.

 

[I6JQdr06]

I’ve never seen anyone demonstrate that masteron actually lowers serum e2. I’ve also not really seen anyone explicitly say that it does, so that’s somewhat moot.

My understanding is that people generally consider DHT derivatives to lower E2?

 

[1Megaman]

I cruise on 200mg test 150mg primo tested at 6 weeks my e2 is at 22 my test is at 1180ish. 200mg test alone tested at 6 weeks my e2 gets into the 90’s my test is the same 1180ish. Did 200mg test 200mg mast e at 6 weeks in my e2 was 90ish. Mast did nothing for my e2. Haven’t ran EQ or DHB yet, I do have some and when I run it I will pull bloods and check. But I don’t think this is a rule for everyone I think it’s hit or miss among people. I always read guys saying mast lowers e2 but it defiantly didn’t do it for me. Pull bloods and check for yourself.

 

[I6JQdr06]

I cruise on 200mg test 150mg primo tested at 6 weeks my e2 is at 22 my test is at 1180ish. 200mg test alone tested at 6 weeks my e2 gets into the 90’s my test is the same 1180ish. Did 200mg test 200mg mast e at 6 weeks in my e2 was 90ish. Mast did nothing for my e2. Haven’t ran EQ or DHB yet, I do have some and when I run it I will pull bloods and check. But I don’t think this is a rule for everyone I think it’s hit or miss among people. I always read guys saying mast lowers e2 but it defiantly didn’t do it for me. Pull bloods and check for yourself.

I’ve seen a similar trend in my blood work. Primo to test at similar ratios to you cut my E2 in half. Masteron didn’t.

 

[effswithtren]

I have bloodwork showing primo, DHB, and EQ lowering my E2 vs what it’d be absent said compounds. It’s very individual though. Some people it radically lowers E2, others it doesn’t do dick. Without your own personal data, the thought exercise is fairly useless.

 

[I6JQdr06]

I have bloodwork showing primo, DHB, and EQ lowering my E2 vs what it’d be absent said compounds. It’s very individual though. Some people it radically lowers E2, others it doesn’t do dick. Without your own personal data, the thought exercise is fairly useless.

Have you taken any non aromatising compound which haven’t lowered your E2? Any DHTs, etc?

 

[jJjburton]

People seem to think that DHT derivatives are anti estrogenic but I’m not convinced this is the case. Am I right in saying that these are the compounds which are regularly reported to show estrogen-attenuating activity?

Boldenone
1-test (DHB)
Primobolan

Seems to me the common feature of these three compounds is the 1(2) double bond.

If my conjecture is correct, stenbolone and turinabol will also lower E2 levels. Does anyone have any anecdotal evidence of this being the case?

Does anyone have any anecdotal evidence of Masteron, anavar, or winstrol lowering their E2? This would support the DHT hypothesis.

Note: when I say “anecdotal evidence”, I mean supported by before and after blood work.

Masteron however it did, lessened my gyno or shrunk it to a very low and less puffy point. Not sure what mechanism caused this, but it did

 

[Iron_Yuppie]

My understanding is that people generally consider DHT derivatives to lower E2?

Some number of people also consider the earth to be a flat disk, so I wouldn’t spend a lot of time looking into every crackpot theory that gets dumped on the unsuspecting masses.

 

[I6JQdr06]

Masteron however it did, lessened my gyno or shrunk it to a very low and less puffy point. Not sure what mechanism caused this, but it did

If you look at the literature, it was considered to interfere with the estrogen receptors in breast tissue. But then later studies refuted this idea.

 

[effswithtren]

Have you taken any non aromatising compound which haven’t lowered your E2? Any DHTs, etc?

Ok so far I’ve fucked with…jeez. Let me think.
Test, tren, deca/NPP, mast, DHB, primo, EQ, var, winstrol, dbol, sdrol, drol, and mtren.

Only the three listed in the earlier post lowered my E2. I wouldn’t expect any others to either. But again, more importantly, this is very individual. They may lower your E2 a lot, a little, or even increase it. What it does for someone else isn’t useful to anyone but them. Running an experiment on yourself and assessing via bloodwork is the only way to produce a useful answer to this query.

 

[RiceNKimchi]

But I don’t think this is a rule for everyone I think it’s hit or miss among people. I always read guys saying mast lowers e2 but it defiantly didn’t do it for me. Pull bloods and check for yourself.

It's a hit or miss. Some can get off an ai on a cruise with a little primo or mast added. I could not either. It did not drop enough to get off. Maybe if I ran much higher dht doses but I'm also looking at the ROI on health during the cruise.

 

[I6JQdr06]

It's a hit or miss. Some can get off an ai on a cruise with a little primo or mast added. I could not either. It did not drop enough to get off. Maybe if I ran much higher dht doses but I'm also looking at the ROI on health during the cruise.

I’ve never seen any evidence of mast achieving this (labs), have you?

 

[RiceNKimchi]

I’ve never seen any evidence of mast achieving this (labs), have you?

Only acedotal posts I have seen personally. In my personal labs... I'd have to dig through the old files.. adding mast did drop my estrogen but not significantly, it definitely could have been a few factors though.

I thought it was worth a try on a cruise as I bloat some on 250 test. 200 mast did reduce my bloat but did not change bloods enough to get off my regular ai wkly dose. I don't care to go higher in risk of effecting lipids and other stuff

 

[outphase]

Blood results from 12 weeks of primo on top of trt. 160mg/week TRT dose, added 100mg primo.

Before:

After:

No other changes to diet, regimen, or activity. Both draws taken exactly 24 hours after injection.

 

[RiceNKimchi]

An article on it, if you haven't seen

Primobolan / Equipoise Crashed my E2 – Help!

Understand the complex interaction of Primobolan and Equipoise with estrogen levels, symptoms of low estrogens, and practical decision-making strategies for managing these effects in AAS users.

thinksteroids.com