Bloodwork after 10 weeks of 250mg Test Cyp

Uncle Bub

New Member
Just got my bloodwork results after my first 10 weeks on TRT. I also currently using Tirzepatide 15mg, Reta 6mg, and the past couple weeks added in 2iu HGH nightly. Using the HGH along with BPC 157/TB500 to help heal bicep tendinitis. I plan to stay on 250mg test as a cruise dose going forward and will look to run my first cycle relatively soon. Likely just 500mg test for the first one.

I'm 38 years old, 6'2 277lbs (down from 350lbs in May) and my total T level was 502 before starting on test C. Since my total T level was in range my PCP didn't order anymore tests for me to get Free T or estradiol levels. Had some other blood work done back in the spring (CBC, CMP, TSH, T3, T4, Lipid panel) and mostly was all good. My ALT (71) was high back then (57 now), so was my LDL (122) and non HDL (146). My RBC, HGB, and HCT were all in range before TRT but elevated now. If I was better hydrated before testing and hadn't slacked some on my cardio I think those would have likely been fine this time.

My estradiol (130) is concerning to me but I will say I haven't noticed much in the way of effects of it being high. No gyno just some body fat there. Feel fine and libido is strong. No problem getting erect but maybe a little desensitized as it is taking longer to get off and sometimes the erection isn't as strong. My urine stream has changed since taking TC. It's not as strong a stream and it fucking goes in all kinds of directions which is annoying. I have some Arimidex but I haven't taken any yet because I felt fine and didn't notice much signs of estrogen. How much would you suggest I start taking, full 1mg or less? And how often?

Anything else in the testing that looks concerning or any advice moving forward? Thanks
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I would donate blood. Keep losing fat so the E2 goes down. And maybe take an AI to get in it check till it does go down. If you wait for symptoms that means damage has already been done. I am more into preventative then reactive when dealing with life.
 
I would donate blood. Keep losing fat so the E2 goes down. And maybe take an AI to get in it check till it does go down. If you wait for symptoms that means damage has already been done. I am more into preventative then reactive when dealing with life.
Gonna start with 0.25 adex a few times a week for a while and see if that can bring it down. Gonna keep on cutting, hoping to get down to around 20% BF and go from there.

I was going to up the test soon and run a cycle but I gotta get the E2 in range first. If I can't manage it at 250 then I have no chance of managing it when I'm on 500+.

I'm glad I did blood work first before going into a cycle. I wouldn't have any idea the estradiol was so high.
 
Gonna start with 0.25 adex a few times a week for a while and see if that can bring it down. Gonna keep on cutting, hoping to get down to around 20% BF and go from there.

I was going to up the test soon and run a cycle but I gotta get the E2 in range first. If I can't manage it at 250 then I have no chance of managing it when I'm on 500+.

I'm glad I did blood work first before going into a cycle. I wouldn't have any idea the estradiol was so high.
Getting in range is just a matter of trail and error and blood testing.
500 mg/week doesn't mean you can just double your AI for the same results. That will be trail and error too.
 
Why are you going from one cycle to another, 250mg for 10 weeks to 500mg for a second cycle?

Your testosterone is high out of range. It is fucking up your cholesterol and driving your e2 sky high and your hematocrit way up out of range.

What are you trying to do to yourself by doubling it?

Take a break.

Geez, why even do bloodwork of you are just going to engage in denial? "Hydration and cardio" does not get 55.6 hematocrit down into the 40s. The bloodwork is telling you something.

Your e2 would be normal if you lowered your testosterone. Your body metabolizes testosterone, and one of the metabolites is e2. You do not need an AI, you need to lower your dose and get our total test and free test back into some reasonable numbers within the human reference range. And you need to stay there a while and let your hematocrit and cholesterol normalize.
 
Your values were normal before this cycle that you call TRT.

Get your blood values normal again and stay there a while. Do this the right way.

The urine thing is your prostate. Injecting steroids often has that effect. Again, same issue, same cause.
 
Why are you going from one cycle to another, 250mg for 10 weeks to 500mg for a second cycle?

Your testosterone is high out of range. It is fucking up your cholesterol and driving your e2 sky high and your hematocrit way up out of range.

What are you trying to do to yourself by doubling it?

Take a break.

Geez, why even do bloodwork of you are just going to engage in denial? "Hydration and cardio" does not get 55.6 hematocrit down into the 40s. The bloodwork is telling you something.

Your e2 would be normal if you lowered your testosterone. Your body metabolizes testosterone, and one of the metabolites is e2. You do not need an AI, you need to lower your dose and get our total test and free test back into some reasonable numbers within the human reference range. And you need to stay there a while and let your hematocrit and cholesterol normalize.
I didnt say I was going to up it to 500 right now. Before the blood work my original plan was to use 250 as a TRT/cruise and with an occasional blast which my first one was going to start soon at 500 until I got these results back.

Now that I have the testing after just running 250 and with the help of others including yourself, it appears that is going to be too much for a TRT dose. I'm going to follow your advice and work on finding the right amount of test that will get all of these markers within a normal range for a while before I try to run any cycles.

Thanks for the advice, this is the type of knowledge I was hoping to get out of this thread.
 
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