Cheap Pfizer/Hospira BAC may be about to end

What kind of degradation are you referring to? The 28 day thing is for sterility concerns in multi-use multi-patient setting. You could add USP BA to sterile water. You may not get the same pH as from pre-mixed solution.
BA degrades that is why sterility is an issue. Anyway, no point in dragging this discussion unnecessary long. Why would PH of a self constituted solution using Hospira water for injection be a matter of worry to someone using Hospira bac water beyond listed shelf life? :D
 
I have sterile water from Medex. Don't have much use for it other than to prove to sources that their peptides still gell when mixed with just sterile water. Tried it for botox, it works, but as painful as mixing botox with BAC water. So makes no sense to use it for anything other than single injection vials like 2mg Tesa.
 

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I have sterile water from Medex. Don't have much use for it other than to prove to sources that their peptides still gell when mixed with just sterile water. Tried it for botox, it works, but as painful as mixing botox with BAC water. So makes no sense to use it for anything other than single injection vials like 2mg Tesa.

That's really the ideal for all peptides. Single dose vials reconstituted with WFI, immediate use, no preservative excipients (since there's no free ride, they all cost some peptide purity while extending shelf life).

If only they didn't charge such a high premium for single dose vials. On top of that, I assume they're slow movers so god only knows how long they've been sitting around.
 
That's really the ideal for all peptides. Single dose vials reconstituted with WFI, immediate use, no preservative excipients (since there's no free ride, they all cost some peptide purity while extending shelf life).

If only they didn't charge such a high premium for single dose vials. On top of that, I assume they're slow movers so god only knows how long they've been sitting around.
You would be surprised. Non BAC water tends to sell more. BAC does crazy things in certain people, and will absolutely kill sick babies
 
You would be surprised. Non BAC water tends to sell more. BAC does crazy things in certain people, and will absolutely kill sick babies

Unfortunately infants make for good examples of the harmful effects of things that don't necessarily show obvious symptoms in adults.

Plenty of autopsy examples of unfiltered drugs that didn't reconstitute properly, stopper particles, "sterile floaters", glass, all resulting in organ failure and death in infants.

In line filtration has long been observed to reduce complications and speed up recovery time in hospitalized adults, and since 1969, it seems the only argument against filtration has been cost and the burden on nurses having to handle filters.

So it's been standard practice to filter everything injected into infants, IV or Syringe, at the "best" hospitals for a long time, but still optional.

Still arguing over this 55 years since the problem of particulates was first discovered.

"Particulate contamination due to infusion therapy (administration of parenteral nutrition and medications) carries a potential health risk for infants in neonatal intensive care units (NICUs). This particulate consists of metals, drug crystals, glass fragments, or cotton fibers and can be generated by drug packaging, incomplete reconstitution, and chemical incompatibilities. In-line filters have been shown to remove micro-organisms, endotoxin, air, and particles in critically ill adults and older infants, but its benefits in newborn remain to be demonstrated. Moreover, 50% of inflammatory episodes in the setting of NICUs are blood culture-negative. These episodes could be partly related to the presence of particles in the infusion lines."

 
You are trained to do this to yourself and others?
I did this to myself following the guide from botox official website. Got better results than when trained and licensed nurse did it. I would not do that to others for liability and just common sense reasons. They could follow my example, but on their own.

I'm using the green owen mufford pen. It's very convenient for injections with a single hand. You dial the number of units in advance and just need to press the trigger for injection, no need to keep pushing like with humapen and clones.

Standard dilution is 2.5ml of sodium chloride 0.9% for 100iu vial of toxin. Then 0.1ml (10 U100 syringe units) is 4 IU of toxin.

I did filter China-sourced toxin with 0.22um nylon 4mm syringe filter for extra safety, toxin worked just like it should.

If you use sterile water or BAC water instead of sodium chloride, it stings for about 10 seconds after injection. Unpleasant, but tolerable.

My friends liked my results so much they ordered kits for themselves.




Edit: added links to pen and Botox guides
 
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Yes, very easy to do if you've done any subq or IM pins before. Pins are actually IM, but the depth is more in line with subq.

Interesting data point: pet insulin syringes (U40) match the syringe units to toxin IUs when it's 2.5ml to 100IU per guide. So if you need something other than standard 4 IU pins and want to avoid math, pet 31G syringes are a good option. Just make sure they are from a reputable manufacturer, marked sterile and non-pyrogenic. 4 units on a pet syringe is 0.1ml
 
That said, if you are going to use bac years beyond sell by date, why not just buy sterile water that is waaay cheaper and BA that lasts waaay longer and add your BA to the Sterile water when its time to use?
i have gone that route with making my own bac water and it was fine, i use ALOT of bac water anyways so it doesn't go bad around my house, lol , couldn't help but pick up a couple cases of this Hospira tho,,
 
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