cholesterol and steroids

[Geoff]

We know that steroids reduce HDL (good cholesterol), and increase bad cholesterol (LDL). Low HDL and high LDL, and more importantly, a poor ratio between the two do lead to increased cardiovascular risk.

Orals appear to have a greater impact than injectables. We also know that compounds that do not aromatize lower HDL, while aromatizable androgens such as Test Enanthate are more neutral. This leads to a few questions:
- if injectables are better than orals, is injectable winstrol and dianobol better from a cholesterol perspective than their oral equivalent, or does it not make a difference.
- what other steroids have less negative impact on a users' HDL and LDL levels
- what cholesterol lowering drugs are more appropriate to take while on a steroid course. I am not keen to take Lipotor (a statin) due as it may add further stress to my liver / body etc which is already under stress from the juice. What is your opinion of Fibrates (Tricor) as a cholesterol treatment while on juice, or other treatments? What about Niacin (Nicotonic acid).

I already watch my diet very closely (low in saturated fats), take lecithin and omega 3, 6 and 9 supplements, yet struggle with my cholesterol. My doctor is also aware of all of the above issues, and conducts regular blood tests. However, he is not an expert in anabolics, and is also uncertain of the impact of the various treatment options, while taking juice.

 

[einstein1905]

The reason test is more "neutral" with regards to cholesterol is because, yes, it aromatizes to estrogen, which has favorable effects on cholesterol levels. That's why nolva throughout a cycle is doubley beneficial....it is a SERM, which is an agonist in the right places and an antagonist in the right places.You geet a positive estrogenic effect in the liver and bone and an anti-estrogenic effect at the mammary, as well as many other places.

 

[bigmack]

First, methandrostenolone and stanozolol are 17-alpha-alkalyted in both the oral and injectable form. With that being said, both have binding effect on various receptors that are activated by both estrogens and glucocorticoids in the liver as well as various other tissues. In fact, they may act as antagonists to specific receptors that estrogen, among other circulating hormones, normally would bind to that help to regulate lipoprotein levels in vivo.

Although Tricor (fenofibrate) does not alter the same metabolic pathway in the liver as the statins, there has been liver associated complications with use of this drug including elevated enzymes and hepatitis. I would imagine then that one would want to avoid this medication as well when taking a potentially liver toxic steroid such as methandrostenolone or stanozolol. Just to be on the safe side. In addition, most studies show that the injectable testosterones have less of an effect on lipoprotein levels although there is minor changes in HDL.