Dbol/ Anadrol Liver Toxicity

[la_triathlete]

Hey guys,

I have not been on the board for a while- sorry for the long hiatus, its nice to be back and reading all this good stuff. With that said, please indulge my typical long winded post.

So, I am hoping to pick your brains regarding the use of Dbol and Anadrol, and their potential hepatotoxic effects. I understand the mechanism behind why they can cause liver toxicity (c-17alpha alkylated), but what I am wanting people to help me out with is understanding what a safe doses and durations of use might look like. Let me give you a quick background story:

About a year ago, I got some really weird viral infection that cause me to have pancreatitis and liver distress. I was in the hospital for about 2 weeks, had sky high liver and pancreatic enzymes, and pain that was bad enough to warrant giving me morphine (which was the BEST thing I have ever taken- I now understand why people can so quickly become addicted). Right before all this happened, I had been on a winny (50mg EOD)/ test (400mg cyp/ wk) cycle for about 12 weeks. I know that winny has potential hepatotoxic effects, so I am assuming my use of it aggravated the situation, but was not the cause of it. I have since made a full recovery.

Ok, with all that said, I am STRONGLY considering doing a cycle that incorporates using dbol and anadrol. The cycle is the exact same one that is diagrammed in the Anabolics 2004 book on page 47: 22-week Super-Blitz Lean Mass Cycle. I am not meaning to break any copyright laws, but for those who dont have the book, the cycle looks as follows:

Wk 1-6: 400mg T. Prop/ wk AND 100mg ED Anadrol
Wk 7-12: 225mg Tren/ wk AND 400mg Primo/ wk
Wk 13-18: 400mg Deca/ wk AND 40mg Dbol ED
Wk 19-24: 400mg T Prop/ wk AND 225mg Tren/ wk AND 400mg Primo/ wk

With this cycle in mind, I am wondering if I am taking too much of a chance with the Drol and Dbol given my past liver toxicity issues. Given that I would only be taking each for 6 weeks, with a 6 week separation in their administration, I was assuming that I would minimize any toxic effects.

What are your thoughts on this? Is there any chance that my liver might now be sensitized to c-17alpha alkylated drugs? Might liquid Dbol (Reforvit) potentially have less toxic sides since it is injectable (no first pass liver stressing effects)?

Well, I look forward to hearing what you guys have to say.

Thanks a million,

LA

 

[gyno_ghost]

About a year ago, I got some really weird viral infection that cause me to have pancreatitis and liver distress. I was in the hospital for about 2 weeks, had sky high liver and pancreatic enzymes, and pain that was bad enough to warrant giving me morphine (which was the BEST thing I have ever taken- I now understand why people can so quickly become addicted). Right before all this happened, I had been on a winny (50mg EOD)/ test (400mg cyp/ wk) cycle for about 12 weeks. I know that winny has potential hepatotoxic effects, so I am assuming my use of it aggravated the situation, but was not the cause of it. I have since made a full recovery.

Ok, with all that said, I am STRONGLY considering doing a cycle that incorporates using dbol and anadrol. The cycle is the exact same one that is diagrammed in the Anabolics 2004 book on page 47: 22-week Super-Blitz Lean Mass Cycle. I am not meaning to break any copyright laws, but for those who dont have the book, the cycle looks as follows:

Wk 1-6: 400mg T. Prop/ wk AND 100mg ED Anadrol
Wk 7-12: 225mg Tren/ wk AND 400mg Primo/ wk
Wk 13-18: 400mg Deca/ wk AND 40mg Dbol ED
Wk 19-24: 400mg T Prop/ wk AND 225mg Tren/ wk AND 400mg Primo/ wk

With this cycle in mind, I am wondering if I am taking too much of a chance with the Drol and Dbol given my past liver toxicity issues. Given that I would only be taking each for 6 weeks, with a 6 week separation in their administration, I was assuming that I would minimize any toxic effects.

What are your thoughts on this? Is there any chance that my liver might now be sensitized to c-17alpha alkylated drugs? Might liquid Dbol (Reforvit) potentially have less toxic sides since it is injectable (no first pass liver stressing effects)?

Hello LA,

In my opinion, there are equally valid reasons why you should and shouldn't undertake the cycle you've listed. Your past complications, of course, are the most compelling reason to steer clear of liver-toxic substances. Winstrol is toxic to the liver, and although you were only dosing every other day, 12 weeks is nonetheless quite a long time to endure a 17-aa steroid.

That said, if I am reading your post right, your last cycle was approximately one year ago. Given that length of time and the medical attention you received, one could reasonably argue your liver has more or less fully recovered. The doses you have listed are certainly not on the extreme end of oral administration. And, as you mentioned, you'll be taking six weeks off during the midsection of your cycle; I believe the literature suggests that you should be off 17-aa steroids at least as long as you are on them, so your six-week break should be sufficent. If you were to experience any trouble, I would suspect it'd be at the tail end, when your liver is dealing with having endured 12 weeks of 17-aa exposure out of a possible 18.

I have no experience with injectable Dbol but I believe you are correct to assume that such a product would spare your liver the toxic effects of oral administration. As you mentioned, injectables skip the first-pass through the liver; indeed, oral steroids like traditional Dbol are have the hydrogen atom in the 17th position replaced with a carbon group to withstand the liver, and since you'd be injecting and not swallowing, I don't think that particular aspect of the drug's chemistry would apply here. I could be wrong, though, and would ask the veterans here to correct me.

Incidentally, there has been an interesting discussion regaring liver toxicity here:

https://thinksteroids.com/community/threads/6282

Best of luck with your cycle. Keep us posted as to what you decide to do, and also of your progress with your gains.

GG