DNP + Semaglutide ?? Is running both safe ?? Will slow digestion be an issue ??

[Tr3nbal0n3]

I need to get absolutely shredded as soon as possible. Is it a bad idea to run DNP while also being on Semaglutide ? I came off DNP after a few days of being on it because of the intense hunger side effects it caused me to have. I almost messed up the diet a few times on it. I felt just as hungry on DNP as I did on MK677. I figured I’d use Semaglutide for appetite suppression + DNP for rapid fat loss.

I know GLP1 agonists slow down digestion, and my concern is having DNP pills in my stomach being digested slow sounds kinda scary. Especially since DNP can be deadly. The 36 hour half life of DNP + slow digestion leads me to believe something could potentially go wrong. Does anybody have any experience with running both compounds together?? Or does anyone know if it’s even safe to do so.

 

[Anonymous35]

I run TRT - (I have dipped into TRT+ at times but this site has taught me it's not really worth pondering anything other than Test at sane levels until you get body fat down to reasonable levels).

So for full disclosure I currently run about 80-120 mg of Test cyp weekly. I occasionally add in 40-80 of Primo instead of Aromasin.

I have plenty of other compounds at my disposal but lingering here has again taught my they are pointless to use for cutting unless diet,. exercise and sleep are on point (which is rare for me in my career right now).

I understand where you might see some hypocrisy in my advice. You are free to self-experiment as you see fit. Just be open to the possibility you're wrong and be willing to change course.

I implore you to at least qualify your advice on meds being run with "there is zero scientific evidence to support this suggestion." It is possible the evidence will change as time goes on. It's possible you have done more research and know more anecdotal reports for the advice you are suggesting (combining Reta and Tirzepatide) but we really need to be careful about propagating these mixes of GLPs. I'm truly not trying to preach to you.

I presume you're an adult and and are free to do as you see fit. But we need to be clearer on the advice offered in this forum... it's either:
- i. Scientific fact: cite sources

- ii. Anecdotal reports: n = (hopefully a high number of people from various walks of life)

- III. Bro-science. ... let's eliminate bro-science in here. We're generally a classier group of drug addicts...lol

Reta is as today still on triall there is litteraly a study from lilly which gonna start on november 2025 so no i don’t have studies with a mix of glp 1

But from my experience i have less side effects from 5mg/ 5mg tirz reta than 10mg tirz alone
And feeling better but thats my own personal experience
But dnp is still worse than reta belive me
I’m a pharmacy technician so i have a lot of knowledge about med

Btw if you add primo it’s not trt amymore it’s a cycle
And if you need something to control your e2 on trt then maybe the dose is too high or you should split the dose more often

 

[RandallFlagg]

Reta is as today still on triall there is litteraly a study from lilly which gonna start on november 2025 so no i don’t have studies with a mix of glp 1

But from my experience i have less side effects from 5mg/ 5mg tirz reta than 10mg tirz alone
And feeling better but thats my own personal experience
But dnp is still worse than reta belive me
I’m a pharmacy technician so i have a lot of knowledge about med

Btw if you add primo it’s not trt amymore it’s a cycle
And if you need something to control your e2 on trt then maybe the dose is too high or you should split the dose more often

I agree on all points (including the cycle...which is why I stopped kidding myself I was running 'roids to get jacked and dropped the "extra" stuff). I haven't been working out nearly enough to justify anything beyond Test cyp for the last few months...but some day...lol.

Your advice on all points above is spot on. To be honest, I don't even recall what we might have been disagreeing about...lol (but seriously, yeah, I agree with all you just said above). The problem is not everyone who reads advice on the internet is going to stop and question the advice. They'll just justify in their head "some dude on the 'net said it was cool..." And run with it.

My hope is that we have enough discussion and debate to at least make some people pause and question whether certain meds are actually safe for them with ZERO medical supervision.

 

[Anonymous35]

I agree on all points (including the cycle...which is why I stopped kidding myself I was running 'roids to get jacked and dropped the "extra" stuff). I haven't been working out nearly enough to justify anything beyond Test cyp for the last few months...but some day...lol.

Your advice on all points above is spot on. To be honest, I don't even recall what we might have been disagreeing about...lol (but seriously, yeah, I agree with all you just said above). The problem is not everyone who reads advice on the internet is going to stop and question the advice. They'll just justify in their head "some dude on the 'net said it was cool..." And run with it.

My hope is that we have enough discussion and debate to at least make some people pause and question whether certain meds are actually safe for them with ZERO medical supervision.

Don’t worry, i was just there to help you
Maybe i was a bit too direct

That you body your choice at the end
But if i can change your mind to drop the dnp for something safer, i will tried to do it

For trt i used test decanoate longer half life 10 days compared to 5 days (cypio)
Especially if you do 1 shot a week