Does Arimidex decrease estrone levels?

[benrock]

aromisin is a sucicide inhibiter , it stops all converson which is not always good , but it your way out of range it may help like it did for me , our sponser selles it ,

i tryed arimedex once but it made me deprerssed like my estrogen went up , im not sure i never got blood drawn though .

now i use 100mg zinc and eat alot of broccoli and my levels have been in range

 

[maxzax]

Benrock,

The levels of Zinc your taking are extremely high, consider lowering it. I believe Swale recommends no more then 40mg daily. Also I tried a high dose of zink like you were doing previously and it gaven stomaches after awhile, I don't know the relation. Just something to keep in mind.

Are you still on aromisin?

Do you any information on dosages for aromisin?

How many milligrams in each aromisin tablet? What dosage were you on?

My E2 is 44 range <50
My Total E is 219 range 40-115

Thank you!!!

 

[MANWHORE]

I'm not an 'arborist' or whatever you call those guys. But that is the most beautiful tree that I've ever seen

I'd like to plant one of those in my backyard

 

[benrock]

i can only get research aromisin , but 2 companys are legit as far as i know are pnp and ag guys , its 25mg per tab if you get from a doctor , and there is no impact on lipids levels from what i here but mine didnt change , its worth a shot , start with 1/2 cc of the liquid and taper down until you feel better lik 1/4 cc per 5 days , worked for me , arimedex was harsh on my mood , aromisin only gave me a few hot flashes which going through hrt we all have gotten

 

[Random987]

I am trying to determine if there are substantial differences in the three currently recognized specific aromatase inhibitors/inactivator:

Letrozol/Femara((R)), Anastrozol/Arimidex((R)) or Exemestan/Aromasin

I think Femera and Arimidex are nonsteroidal, while Aromasin is sterodial. Probably the biggest difference in the three is the fact that Aromasin doesnt just slow the production of aromatase after it binds to the enzyme, it stops the enzyme's production process completely.

Specifically, I would like to know if all three tend to reduce E2, but increase Total Estrogens. Or if any one of the three is better at reduce all estrogens. There really isn't a lot of research on this as the field is dominated by breast cancer research. I am one of those folks that has a good E2, but high Total Estogens.

Also, there is another option there is a pure antiestrogen drug called fulvestrant. It is my understanding that Fulvestrant is an estrogen receptor antagonist with no agonist effects. It is an estrogen receptor downregulator. This means that fulvestrant doesnt just stop estrogen from getting to the receptor, it destroys the receptor itself.

 

[pmgamer18]

Here is a link on 13c vs DIM and the DIM lowered my DHT I was 3x's over the top of the range.
http://www.lef.org/magazine/mag2002/jan2002_report_i3c_01.html
At this link they talk about the different drugs used to keep Estrogens down and E2.
http://www.t-nation.com/findArticle.do?article=150estro
I tried Evista and it did nothing to lower my high E2. I had a lot of problems from high E2. Bad ED, had to use a pump and cock ring to have sex with my wife but could not reach an orgasm. My skin on my upper body and face looked like I had a bad sunburn and I was hot & sweating a lot. I had panic attacks in the middle of the night, my prostate hurt and my voiding was slow. I had a lot of bladder infections, I could not go into my spa I would break out in a rash from the heat. The back of my calfs had a bad rash that would not go away and if I eat shrimp I broke out in hives. My Free T levels was never good. All of this went away when I used Arimidex on half of a one mg. pill everyday. But to keep my E2 down Arimidex is to strong I was doing 1/4 of a pill every 5 days and going to low. I now use Indolplex/DIM and when it is very bad I add Arimidex to the mix. I started on TMG to see if it will get my Total E down and will have the test back next Tue. I will post the results.
I also take Zinc/Copper to help keep my E's down and find it helps with the volume of my sperm. Here is what I take.
http://www.ritecare.com/prodsheets/PHY-15336.html
http://www.myvitanet.com/zincop100cnt.html
http://www.myvitanet.com/tmgtr75120ca.html
I also take Maca to keep my hormones leveled off. I buy it by the KG. and take two one half tsp. full a day one in the morning and one in the afternoon. It is also keeping my BP down.
http://macaweb.com/
Phil

 

[Random987]

UH-OH! You cited to an article by "Cy Wilson". Swale, back away from the keyboard. Slowly....Slowly...

At this link they talk about the different drugs used to keep Estrogens down and E2.
http://www.t-nation.com/findArticle.do?article=150estro

Phil

 

[pmgamer18]

O well how is one to know. But at the time there was not much out there on the meds for lowering E2 and this was a big help.
Phil

 

[Random987]

No, it's all good. Swale used to post on test.net a few years ago, when they were transitioning from useful information to blatant self promotion and marketing (not to mention them censoring all posts that did not toe the party line). Swale and "Cy" went round and round a number of times.

O well how is one to know. But at the time there was not much out there on the meds for lowering E2 and this was a big help.
Phil

 

[frankwhardy]

Here is a link on 13c vs DIM and the DIM lowered my DHT I was 3x's over the top of the range.
http://www.lef.org/magazine/mag2002/jan2002_report_i3c_01.html
At this link they talk about the different drugs used to keep Estrogens down and E2.
http://www.t-nation.com/findArticle.do?article=150estro
I tried Evista and it did nothing to lower my high E2. I had a lot of problems from high E2. Bad ED, had to use a pump and cock ring to have sex with my wife but could not reach an orgasm. My skin on my upper body and face looked like I had a bad sunburn and I was hot & sweating a lot. I had panic attacks in the middle of the night, my prostate hurt and my voiding was slow. I had a lot of bladder infections, I could not go into my spa I would break out in a rash from the heat. The back of my calfs had a bad rash that would not go away and if I eat shrimp I broke out in hives. My Free T levels was never good. All of this went away when I used Arimidex on half of a one mg. pill everyday. But to keep my E2 down Arimidex is to strong I was doing 1/4 of a pill every 5 days and going to low. I now use Indolplex/DIM and when it is very bad I add Arimidex to the mix. I started on TMG to see if it will get my Total E down and will have the test back next Tue. I will post the results.
I also take Zinc/Copper to help keep my E's down and find it helps with the volume of my sperm. Here is what I take.
http://www.ritecare.com/prodsheets/PHY-15336.html
http://www.myvitanet.com/zincop100cnt.html
http://www.myvitanet.com/tmgtr75120ca.html
I also take Maca to keep my hormones leveled off. I buy it by the KG. and take two one half tsp. full a day one in the morning and one in the afternoon. It is also keeping my BP down.
http://macaweb.com/
Phil

Phil,

Did you post your lab results somewhere on whether the TMG is helping with lowering your total E? (Sounds familiar, but I may have missed it.) Also, someone may have already posted it, but iHerb is another source for the Indolplex formulation of DIM:

http://store.yahoo.com/iherb/indolplex.html

I'm going to be ordering it in the next couple of days.
Frank

 

[SWALE]

I had not heard of TMG lowering DHT. Remember, if true, this can be a negative, as well. Anyone seen any lit on this point?

What TMG does with respect to estrogen metabolism is provide methyl units for the COMT (catecholamine METHYL-transferase--caps added for educational purposes) enzyme, which washes the nasty 4-OHE downstream in its metabolic pathway to beneficial metabolites. Some have deficiencies in their particular COMT isozymes, which result in higher levels of 4-OHE. The strategy is to overcome same by flooding the system with methyl groups.

These additional methyl groups have many other beneficial effects as well, including reducing the generalized inflammatory response most live under. I learned this while researching background information for the lecture I gave to lead off the scientific portion of the A4M conference in Bali last week.

 

[frankwhardy]

Dr. John, if your talking about some of Phil's posts, I think he was indicating that the Dim (Indoplex) was what he believed might have lowered his DHT level, with the TMG possibly being capable of lowering his total E. In my own case, I hope that's true about the DIM, because my DHT level, pre-TRT, is at the very upper end of the range. (If I can get my doctor to order the necessary tests, then I might be able to do a little study on my own, since I'll be trying the DIM pretty soon, I hope.)

 

[frankwhardy]

Does anyone know if arimidex will decreases Estrone levels as well as Estradiol Levels?

In the journal article entitled, "Effects of Aromatase Inhibition in Elderly Men with Low or Borderline-Low Serum Testosterone Levels," a chart (which I've attached) is provided which shows that estrone is decreased as well as estradiol.

(Note: The full text of the article can be found here: http://jcem.endojournals.org/cgi/content/full/89/3/1174)
Frank

 

[Axl]

Good find!! Nice article.

 

[maxzax]

anastrozole

Thanks Frankwhardy,

Excellent Article, Im gonna bring this to my doc hopefully I could convince him to give Adex.

 

[maxzax]

anastrozole

Thanks Frankwhardy,

Excellent Article, Im gonna bring this to my doc hopefully I could convince him to give Adex.

Thanks!!!

 

[KMais]

Anastrozole decreased estrone by high androstenedione pathway?
Anybody know? Any study?