Does microwaving crashed gear degrade potency?!!

I wouldn't put it in the microwave at all but I sure would reheat it before pinning as many times as I had to before throwing it away.
Then what were you asking me why about? My response was clearly towards putting gear in the microwave. I've heated crashed gear. I just don't microwave it.
 
Then what were you asking me why about? My response was clearly towards putting gear in the microwave. I've heated crashed gear. I just don't microwave it.

So he microwaved it a couple times, no big deal. If it was a 100ml vial and he microwaved it 50x for 2 minutes each then you have a point but to toss it over a couple instances is excessive.
 
So he microwaved it a couple times, no big deal. If it was a 100ml vial and he microwaved it 50x for 2 minutes each then you have a point but to toss it over a couple instances is excessive.
Dude. What are you even reading? I never once suggested he toss it. I simply said I wouldn't microwave my own gear.
 
Dude. What are you even reading? I never once suggested he toss it. I simply said I wouldn't microwave my own gear.

I misread your post #42 on this page then. When you said you'd stay away from it I thought you meant from the gear bc you'd toss it. I realize now you meant to stay away from the microwave. My apologies Whoremoans.
 
I am slightly worried that every time I do this (microwaving) I may be degrading the potency.

The short answer is IDK bc there are no studies on the subject, that I'm aware of (and I just scanned MedLine)

The long answer; MW is very unlikely to significantly alter the potency bc the chemical structure of oil soluble AAS are inherently VERY STABLE.

ALL AAS are relatively SMALL polycyclic compounds that are bound thru COVALENT or HYDROGEN bonds.

The relatively small size of AAS
limits their ability to twist or fold about an axis.

While the former covalent bonds are the strongest type of any involved in human physiologic processes, the latter hydrogen bond is relatively weak.

Fortunately for you microwavers, although it's quite likely some of the hydrogen bonds are lysed during the heating process the byproduct is even more unstable than its parent compound.

Moreover the fact parenteral AAS are well solubilized in OIL greatly limits the tendency of any dissociated Hydrogen to remain "free" in solution.

This solubility factor would facilitate the return of any "free" hydrogen to its original position within the AAS molecule

By contrast the INSTABILITY of POLY-PEPTIDE hormones such as GH and Slin, forbid all but passive heating measures.

The difference once again lies in the structural features of polypeptide hormones, as these compounds are amide based AND develop specific FUNCTIONAL folding patterns.

Really it's seems that portion of an AAS molecule which is most susceptible to heating is the ester group, which may be converted to its conjugate acid thru heating of any kind.

Oh another factor to bear in mind MW primarily heats the SOLVENT rather than the solute per say!

Jim
 
Last edited:
The short answer is IDK bc there are no studies on the subject, that I'm aware of (and I just scanned MedLine)

The long answer; MW is very unlikely to significantly alter the potency bc the chemical structure of oil soluble AAS are inherently VERY STABLE.

ALL AAS are relatively SMALL polycyclic compounds that are bound thru COVALENT or HYDROGEN bonds.

The relatively small size of AAS
limits their ability to twist or fold about an axis.

While the former covalent bonds are the strongest type of any involved in human physiologic processes, the latter hydrogen bond is relatively weak.

Fortunately for you microwavers, although it's quite likely some of the hydrogen bonds are lysed during the heating process the byproduct is even more unstable than its parent compound.

Moreover the fact parenteral AAS are well solubilized in OIL greatly limits the tendency of any dissociated Hydrogen to remain "free" in solution.

This solubility factor would facilitate the return of any "free" hydrogen to its original position within the AAS molecule

By contrast the INSTABILITY of POLY-PEPTIDE hormones such as GH and Slin, forbid all but passive heating measures.

The difference once again lies in the structural features of polypeptide hormones, as these compounds are amide based AND develop specific FUNCTIONAL folding patterns.

Really it's seems that portion of an AAS molecule which is most susceptible to heating is the ester group, which may be converted to its conjugate acid thru heating of any kind.

Oh another factor to bear in mind MW primarily heats the SOLVENT rather than the solute per say!

Jim

BOTTOM LINE
The microwaving of oil solubilized AAS should NOT alter the potency to any degree.

However all but passive heating measures should be avoided with those compounds that are PEPTIDE based!
 
The short answer is IDK bc there are no studies on the subject, that I'm aware of (and I just scanned MedLine)

The long answer; MW is very unlikely to significantly alter the potency bc the chemical structure of oil soluble AAS are inherently VERY STABLE.

ALL AAS are relatively SMALL polycyclic compounds that are bound thru COVALENT or HYDROGEN bonds.

The relatively small size of AAS
limits their ability to twist or fold about an axis.

While the former covalent bonds are the strongest type of any involved in human physiologic processes, the latter hydrogen bond is relatively weak.

Fortunately for you microwavers, although it's quite likely some of the hydrogen bonds are lysed during the heating process the byproduct is even more unstable than its parent compound.

Moreover the fact parenteral AAS are well solubilized in OIL greatly limits the tendency of any dissociated Hydrogen to remain "free" in solution.

This solubility factor would facilitate the return of any "free" hydrogen to its original position within the AAS molecule

By contrast the INSTABILITY of POLY-PEPTIDE hormones such as GH and Slin, forbid all but passive heating measures.

The difference once again lies in the structural features of polypeptide hormones, as these compounds are amide based AND develop specific FUNCTIONAL folding patterns.

Really it's seems that portion of an AAS molecule which is most susceptible to heating is the ester group, which may be converted to its conjugate acid thru heating of any kind.

Oh another factor to bear in mind MW primarily heats the SOLVENT rather than the solute per say!

Jim
Fuck yeah, go test!
 
Oh crap I forgot to mention one proviso, my comments exclude testosterone :)

Now that's not to suggest one can pop that vial in the microwave and set it and forget it!

To the contrary there's likely a right way, the wrong way and a lot of variance in between.

Set the MW on medium and heat the product for roughly 20 to 30 second intervals swish and swirl and repeat the process until the precipitate is dissolved.

You can use a HIGH heat but decrease the heating interval. The idea is to generate heat in a relatively "slow" but controlled and deliberate manner.

Venting should NOT be required bc the temps generated should not exceed the vapor temps for the solvent oil.

The latter is important bc if one boils that oil not only is the vial likely to break but oxidation of the AAS is likely increased.
 
Last edited:
FYI
The manufactures (such as Watson) recommendation, "should a visable product develop at the base of the vial of ...... reheat the contents at room temperature and if the precipitate fails to resolve after more than several hours DISCARD THE PRODUCT".

"Forward the vial and its contents to bla, bla, bla, for full credit ........."

So I'd suggest you return that precipitated AAS vial to the UGL manufacturer and obtain an exchange :)

It's nice to know what ones options are
:)
 
Oh I better clarify before some noob ....... I was being facetious with respect to TT.

That's bc microwaving oil solubilized AAS should readily tolerate such a reheating process without significantly effecting potency, providing it's conducted judiciously and in a controlled manner.

I believe it's ironic the proviso portion must even be mentioned, but sure enough some casual AAS clown will place an intact vial in the MW on HIGH for TEN MINUTES and like Ron Popeill, "set it and forget it", believing it's similar to heating some TV dinner!
 
Last edited:
The short answer is IDK bc there are no studies on the subject, that I'm aware of (and I just scanned MedLine)

The long answer; MW is very unlikely to significantly alter the potency bc the chemical structure of oil soluble AAS are inherently VERY STABLE.

ALL AAS are relatively SMALL polycyclic compounds that are bound thru COVALENT or HYDROGEN bonds.

The relatively small size of AAS
limits their ability to twist or fold about an axis.

While the former covalent bonds are the strongest type of any involved in human physiologic processes, the latter hydrogen bond is relatively weak.

Fortunately for you microwavers, although it's quite likely some of the hydrogen bonds are lysed during the heating process the byproduct is even more unstable than its parent compound.

Moreover the fact parenteral AAS are well solubilized in OIL greatly limits the tendency of any dissociated Hydrogen to remain "free" in solution.

This solubility factor would facilitate the return of any "free" hydrogen to its original position within the AAS molecule

By contrast the INSTABILITY of POLY-PEPTIDE hormones such as GH and Slin, forbid all but passive heating measures.

The difference once again lies in the structural features of polypeptide hormones, as these compounds are amide based AND develop specific FUNCTIONAL folding patterns.

Really it's seems that portion of an AAS molecule which is most susceptible to heating is the ester group, which may be converted to its conjugate acid thru heating of any kind.

Oh another factor to bear in mind MW primarily heats the SOLVENT rather than the solute per say!

Jim
This settles it. Dr Jim has spoken :) Maybe if you left in the microwave for a couple hrs it would fuck things up.
 
Back
Top