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Anabolic Steroids

ED Issues Continue

Tyler81 said:
Are you STILL having ED issues :confused:

Why switch to HCG monotherapy? You can always just switch to it when you want to have kids.
Click to expand...

Yep.

Honestly I'm thinking about giving it a shot because I've tried everything with injectable T to get my libido and erections level and I just can't get it right. This issue popped up after about a year and a half (maybe two) at 112mg a week at EOD injection schedule.

I then tried only twice per week injections. No change.

Then lowered the dosage quite a bit at twice a week. No change.

Then lowered the dosage even more and have been doing EOD injections with a little hcg here and there. A little change for the better.

So...I figure I can keep playing with the T or throw more hcg at it and see how it makes me feel. The logic with the hcg monotherapy is to run it for awhile and then try another restart depending on how all my labs/tests come back.
 
LW64 said:
My $0.02...

Regardless of price, 2,500 IU eod of HCG will have your E2 go ballistic. It might make you hornier than a Texas tree frog but you wont be able to do anything about it. I'm surprised he recommended this since your main issue is ED. I dont believe you need that much HCG to keep testicles active, and I distinguish between keeing them active and preserving fertility because for sperm production you need FSH in addition to LH or HCG.

Unless cialis doesnt work for you, the arginine and carnitine are not necessary. What you might try is the arginine/carnitine without cialis.
Click to expand...

I'd take the libido with no erections at this point.

The cialis doesn't work consistently for me so I am going to go ahead and give the arginine and carnitine a shot as well. They are both cheap - I got a few months supply off of iherb for like $30.

If anyone here frequently gets their hcg from overseas (reliably) PM me what you are using.
 
Gluck with the HCG. I tried it briefly and yeah you gotta watch for E2.

Have you ever tried the transdermals or other systems? There is Axiron out now which is a deoderant type system and the advantageous of these transdermals is that they skyrocket your libido and well-being. They boost both T and DHT nicely and i never had to use AI on them for two years. No E2 problems (especially if you have low body fat you should have NO issues)

I wish I could still use the transdermals. I've done two injections and i just dont feel that great on them. Im hoping it will get better as levels are more steady. If it doesnt, i might try the buccal system that you put on your gums.

Gluck man

CubbieBlue said:
Yep.

Honestly I'm thinking about giving it a shot because I've tried everything with injectable T to get my libido and erections level and I just can't get it right. This issue popped up after about a year and a half (maybe two) at 112mg a week at EOD injection schedule.

I then tried only twice per week injections. No change.

Then lowered the dosage quite a bit at twice a week. No change.

Then lowered the dosage even more and have been doing EOD injections with a little hcg here and there. A little change for the better.

So...I figure I can keep playing with the T or throw more hcg at it and see how it makes me feel. The logic with the hcg monotherapy is to run it for awhile and then try another restart depending on how all my labs/tests come back.
Click to expand...
 
Tyler81 said:
Gluck with the HCG. I tried it briefly and yeah you gotta watch for E2.

Have you ever tried the transdermals or other systems? There is Axiron out now which is a deoderant type system and the advantageous of these transdermals is that they skyrocket your libido and well-being. They boost both T and DHT nicely and i never had to use AI on them for two years. No E2 problems (especially if you have low body fat you should have NO issues)

I wish I could still use the transdermals. I've done two injections and i just dont feel that great on them. Im hoping it will get better as levels are more steady. If it doesnt, i might try the buccal system that you put on your gums.

Gluck man
Click to expand...

For some reason transdermals make me agitated as hell. Not sure if it's E2, DHT or something in them. I've even tried a compounded type and I had the same issue. I haven't tried any of the newer stuff yet.
 
CubbieBlue said:
For some reason transdermals make me agitated as hell. Not sure if it's E2, DHT or something in them. I've even tried a compounded type and I had the same issue. I haven't tried any of the newer stuff yet.
Click to expand...

Interesting. Maybe you are more sensitive to the increase in DHT.

I find it interesting how different people react differently to different systems, doses, and dosing methods. It all depends on our individual physiology and it becomes largely about trial and error and when you find something that works dont change a damn thing. It took me about a year to figure out 5g gel was best for me and it worked awesome for about 1.5 years. That was a good time in my life.

Now I am back to the drawing board with injections.
 
Got my labs back and they are all perfect.

This is on 70mg T eod.

Tt : 691 (292-1052)
Shbg:44
E2: 25pg/ml
Igf1: 280
Prolactin: 4.2
Dhea: 326 (240-549)
Dht: 403 (106-719)
Prog: .6 (.15-1.15)
Cort: 12 (2-25)

Soo...not a lot of info there except on paper it all looks good.
 
CubbieBlue said:
Got my labs back and they are all perfect.

This is on 70mg T eod.

Tt : 691 (292-1052)
Shbg:44
E2: 25pg/ml
Igf1: 280
Prolactin: 4.2
Dhea: 326 (240-549)
Dht: 403 (106-719)
Prog: .6 (.15-1.15)
Cort: 12 (2-25)

Soo...not a lot of info there except on paper it all looks good.
Click to expand...

Your Free T has gone down in comparison to where it was a while back when you were running TT in the 900s and had an SHBG that was - what? 20-something?

Run it through the calculator and you'll see what I mean:

Free & Bioavailable Testosterone calculator

TT = 900 and SHBG = 24
Free T is 25, right at the high end of normal.

TT = 691 and SHBG = 44
Free T is 13, now near the low end of normal.

You need a TT around 825 to get you into the middle of the normal range and maybe more if your SHBG goes any higher. I think this can make a big difference for libido. I'd say its time to increase your T dose.
 
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LW64 said:
Your Free T has gone down in comparison to where it was a while back when you were running TT in the 900s and had an SHBG that was - what? 20-something?

Run it through the calculator and you'll see what I mean:

Free & Bioavailable Testosterone calculator

TT = 900 and SHBG = 24
Free T is 25, right at the high end of normal.

TT = 691 and SHBG = 44
Free T is 13, now near the low end of normal.

You need a TT around 825 to get you into the middle of the normal range and maybe more if your SHBG goes any higher.
Click to expand...

Yeah, it's gone down because I'm only injecting 70mg a week. I was injecting around 88mg per week (IIRC) back then.

Like I said, this problem started when I was injecting 112 mg per week at EOD intervals...so...
 
CubbieBlue said:
Yeah, it's gone down because I'm only injecting 70mg a week. I was injecting around 88mg per week (IIRC) back then.

Like I said, this problem started when I was injecting 112 mg per week at EOD intervals...so...
Click to expand...

But back then your SHBG was something like half what it is now!

You've had a HUGE change in your SHBG and that changes the whole picture as far as how much T you need. Adjust your dose for a TT in the low 800s. Go to something like 24 mg eod (84 mg/week).

I've reduced my dose too, but I've only come down a couple points from the max of 25 on Free T because my SHBG hasnt changed very much AFAIK. Yours has doubled! You need more T.
 
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A Population-Based, Longitudinal Study of Erectile Dysfunction and Future Coronary Artery Disease

CONCLUSION: ED and CAD may be differing manifestations of a common underlying vascular pathology. When ED occurs in a younger man, it is associated with a marked increase in the risk of future cardiac events, whereas in older men, ED appears to be of little prognostic importance. Young men with ED may be ideal candidates for cardiovascular risk factor screening and medical intervention.

DISCUSSION
Evidence is accumulating to support the concept that ED and CAD are differing manifestations of a common underlying vascular pathology. The presence of a number of common risk factors, the presence of several known pathophysiologic links, and a number of retrospective association studies have reinforced the idea that the link between ED and CAD is important and real. In the current study, we evaluated the association between the presence of ED and the development of future CAD by prospectively following up a cohort of community-dwelling men for a 10-year period from 1996 to 2005. After accounting for common cardiovascular risk factors, we found that ED was associated with an approximately 80% higher risk of subsequent CAD.
 
Labs about 10 days into 2,500 iu hcg eod:

ESTRADIOL LEVEL 36 <=63 PG/ML
TESTOSTERONE LEVEL 579 (292 - 1052) NG/DL
SEX HORMONE BINDING GLOBULIN 34 (16 - 94) NMOL/L
CALC FREE TESTOSTERONE 12.2 (4.8 - 25.0) NG/DL

Thoughts:
I think the T level will come higher in a few weeks and I'll be able to cut the hcg dosage down. I also just started wellbutrin so we'll see how that effects libido.
 
CubbieBlue said:
Labs about 10 days into 2,500 iu hcg eod:

ESTRADIOL LEVEL 36 <=63 PG/ML
TESTOSTERONE LEVEL 579 (292 - 1052) NG/DL
SEX HORMONE BINDING GLOBULIN 34 (16 - 94) NMOL/L
CALC FREE TESTOSTERONE 12.2 (4.8 - 25.0) NG/DL

Thoughts:
I think the T level will come higher in a few weeks and I'll be able to cut the hcg dosage down. I also just started wellbutrin so we'll see how that effects libido.
Click to expand...

Ur last post u had stated u r way to young... and so on...
HCG @2500 eod is a Health Kick and ur number r wear they need to be. The major underlying problem with ED is even tho u have fixed ur physical symptoms there is no how 2 book to stop thinking about it. I would bet the next time u r with ur chic u have zero issue. u will rock that shit. Once this ED becomes an obsession if its not hard in the am people worry. As hard as it seems no ur ED is a thing of the past. Force it out of ur head and she will do the rest.
 
I think your instincts are right, Cubbie. Your Free T is a bit low; something like 16 would be better. Your SHBG has gone WAY up, so you need more tT. Hang in there; your numbers will come up. I have never seen such a huge increase in SHBG!

[Btw, the lower end of the lab fT range is total bullshit. Who the hell wants a fT of 4.8? On that scale, anything below 10 is not a good result.]
 
LW64 said:
I think your instincts are right, Cubbie. Your Free T is a bit low; something like 16 would be better. Your SHBG has gone WAY up, so you need more tT. Hang in there; your numbers will come up. I have never seen such a huge increase in SHBG!

[Btw, the lower end of the lab fT range is total bullshit. Who the hell wants a fT of 4.8? On that scale, anything below 10 is not a good result.]
Click to expand...

Kinda weird how the E2 is still moderate on such a large hcg dose, huh?
 
Wow If I took that much hcg I'd be jumping off a cliff from e2 issues. Amazing. Cubbie any thought given to cipro being the underlying cause to this Ed? I know people report strange sudden "new" symptoms from the floroquinolones for up to year after taking them. Just a thought.
 
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