Filtering gear, this is so easy I feel like I must be doing something wrong

The other day I was syringe filtering some EQ through a nylon membrane .22um with a 10cc syringe and an 18g needle. Even after heating up the oil it was taking goddamn forever and halfway through the second vial the plunger on the syringe snapped.

I didn’t have another 10cc syringe and I had 3 more vials to go so I decided to filter it all through a 1cc syringe by just leaving the drawing needle and filter in the vials and swapping the barrel back and forth. Lo and behold, it flowed like water and only took like 3 seconds to filter 1cc compared to the 10 minutes it was taking to push 10cc through there.

Did I just discover a filtering hack or is there a reason you shouldn’t swap the syringe back and forth like that? Only drawback was that all the barrel swapping got oil on my hands.
 
The other day I was syringe filtering some EQ through a nylon membrane .22um with a 10cc syringe and an 18g needle. Even after heating up the oil it was taking goddamn forever and halfway through the second vial the plunger on the syringe snapped.

I didn’t have another 10cc syringe and I had 3 more vials to go so I decided to filter it all through a 1cc syringe by just leaving the drawing needle and filter in the vials and swapping the barrel back and forth. Lo and behold, it flowed like water and only took like 3 seconds to filter 1cc compared to the 10 minutes it was taking to push 10cc through there.

Did I just discover a filtering hack or is there a reason you shouldn’t swap the syringe back and forth like that? Only drawback was that all the barrel swapping got oil on my hands.

the next best hack is using ptfe
it flows better
 
The other day I was syringe filtering some EQ through a nylon membrane .22um with a 10cc syringe and an 18g needle. Even after heating up the oil it was taking goddamn forever and halfway through the second vial the plunger on the syringe snapped.

I didn’t have another 10cc syringe and I had 3 more vials to go so I decided to filter it all through a 1cc syringe by just leaving the drawing needle and filter in the vials and swapping the barrel back and forth. Lo and behold, it flowed like water and only took like 3 seconds to filter 1cc compared to the 10 minutes it was taking to push 10cc through there.

Did I just discover a filtering hack or is there a reason you shouldn’t swap the syringe back and forth like that? Only drawback was that all the barrel swapping got oil on my hands.
Were you using a vent needle on the filtered vial? If not, that could explain the resistance.
 
Physics my friend. The surface area of the 10ml plunger is much bigger than the 1ml syringe. The 1ml syringe is much thinner, thus the force you exert to move the plunger 10cm on the 1ml is much greater per square cm than 10cm on the 10ml plunger, despite equal effort.

pascals-law.jpg
 
The other day I was syringe filtering some EQ through a nylon membrane .22um with a 10cc syringe and an 18g needle. Even after heating up the oil it was taking goddamn forever and halfway through the second vial the plunger on the syringe snapped.

I didn’t have another 10cc syringe and I had 3 more vials to go so I decided to filter it all through a 1cc syringe by just leaving the drawing needle and filter in the vials and swapping the barrel back and forth. Lo and behold, it flowed like water and only took like 3 seconds to filter 1cc compared to the 10 minutes it was taking to push 10cc through there.

Did I just discover a filtering hack or is there a reason you shouldn’t swap the syringe back and forth like that? Only drawback was that all the barrel swapping got oil on my hands.
Higher volume syringes are harder to push, just like larger diameter nails are harder to drive.
 
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