GHK CU burns all day - even in a 50ml vial

I mean with 5mg copper orally you will puke, same with zinc, injecting minerals that the body is this sensitive with it makes sense it would cause a reaction. usually happends when taking something really acidic and dont have enough stomach acid

Dident seem like copper have low ph tho from what i could find, tought it would be suuper low

Think it was around 5 so its hard to say if the sting is from the coppers ph or just copper itself

But interesting thing about the free copper ions. the ghk got jano analyzes but stuff like that he cant see
He actually can see it it’s just not always noted in the COA.

Try a 1/2 inch needle (but still SQ - do not do it IM). You really shouldn’t need to dilute it that much though. I put 3mL into 100mg and then add a little extra bac (like 10 units) directly into the syringe for each injection.
 
I mean with 5mg copper orally you will puke, same with zinc, injecting minerals that the body is this sensitive with it makes sense it would cause a reaction. usually happends when taking something really acidic and dont have enough stomach acid

Dident seem like copper have low ph tho from what i could find, tought it would be suuper low

Think it was around 5 so its hard to say if the sting is from the coppers ph or just copper itself

But interesting thing about the free copper ions. the ghk got jano analyzes but stuff like that he cant see
dude im taking like 60mg Zinc per day and easy 35mg at once and im not puking
 
It sucks for some, but not for all. I saw one clinician who has been administering GHK-Cu for decades say that it was probably about 90/10 with the 10% being those who don't have ISR.

My wife is in that 10%. "Luck-eeeE" -Napoleon Dynamite

I say that to say that you're at least in good company. *raises hand*

When injecting ZMA sub-q it's imperative that you have proper zinc levels in your system. Do you take a ZMA supplement?

Also, are you taking straight up GHK-Cu? If so, I highly recommend looking into stacking it with KVA or (ideally) something like Klow that is GHK-Cu, BPC-157, TB-500 & KBV. All of these are synergistic and will help with the ISR.

Did you test your GHK-Cu to make sure it's not an overfill? What is your goal w/GHK-Cu?
Not sure what happened here with this previous post of mine but I'm unable to edit it to prevent confusion. Here's what I meant to say, note the part about GHK-Cu injection was NOT supposed to say "ZMA injection" because that would just be wacky:

It sucks for some, but not for all. I saw one clinician who has been administering GHK-Cu for decades say that it was probably about 90/10 with the 10% being those who don't have ISR.

My wife is in that 10%. "Luck-eeeE" -Napoleon Dynamite

I say that to say that you're at least in good company. *raises hand*

When injecting GHK-Cu sub-q it's imperative that you have proper zinc levels in your system as well. Preferably before starting GHK-Cu injections. Do you take a ZMA supplement?

Also, are you taking straight up GHK-Cu? If so, I highly recommend looking into stacking it with KVA or (ideally) something like Klow that is GHK-Cu, BPC-157, TB-500 & KBV. All of these are synergistic and will help with the ISR.

Did you test your GHK-Cu to make sure it's not an overfill? What is your goal w/GHK-Cu?


I'm also still waiting to hear if you're taking a ZMA supplement (or even just Zinc although you need B6 so your body and fully process it... ZMA has both plus Magnesium and you likely need both if you're not currently supplementing it) before I offer further advice on things you can try.

Zinc opposes copper & you want these in balance (like sodium & potassium) so it's key to taking something like GHK-Cu (aka the copper peptide) and helping w/histamine response. Once you take care of that there are other things you can try but none of them are going to do anything if you're going to add proper zinc into your system to oppose the additional copper first.
 
How are you guys injecting this shit?

Added 100mg to 8ml, dident work. Added it to two vials, dident work. Added it to a 50ml vial and the burn is litteraly all day.
Its even worse then carnitine this monequle. not at 50ml but it stings all day vs carnitine wich is more a dull ache

People are really underselling how much PIP this one got. might try ghk basic next

Need 2cc to get 5mg, wich works on some fatty areas. but this sting cant be good, will lead up to scar tissue and have other
peptides not penetrate (if you are looking to be on this for years to come)

Could possibly add 50ml more and make it 2.5mg per 2ml instead of 1ml but jesus christ.. doubt thats even enough dilution

Any advice?
i pinned 5mg yesterday, had a pip and pain went away after one day, been pinning 5mg for only a week, ill probably lower the dose to 2.5mg ed
 
Just wanted to add that I ran ghk-cu for a significant amount of time and labs showed as copper deficient. I’ve since moved onto oral and ditched the peptide entirely.

The data for injx is weak, speculative and not worth it to me. I prefer retinols for topical use.
 
Just wanted to add that I ran ghk-cu for a significant amount of time and labs showed as copper deficient. I’ve since moved onto oral and ditched the peptide entirely.

The data for injx is weak, speculative and not worth it to me. I prefer retinols for topical use.
GHK-CU is not meant to supplement copper. Definitely not the goal and if anyone told you that, they were beyond wrong.
Take this: Amazon.com

Also check Zinc, as those are competitive and require a proper ratio.
 
GHK-CU is not meant to supplement copper. Definitely not the goal and if anyone told you that, they were beyond wrong.
Take this: Amazon.com

Also check Zinc, as those are competitive and require a proper ratio.
Yeah I know. I saw a comment on zinc, and wanted to throw it out there jic anyone thought it affected blood values.

Thanks for the rec, almost out of the Solaray brand and will switch. Zinc’s low, too. I have some autoimmune issues and checked nutrients on a hunch. Hoping addressing this stuff helps. :)
 

I made a post regarding this shitty peptide and debunking all its claims
 
I take a 100mg vial of GHK-CU
Add 2.8 BAC
0.2 Sodium bicarb solution (8.4%)

Doesn't burn at all really, and it's 33.3 mg/mL conc.

Just don't go beyond 0.2ml of NaHCO₃ - it will move the pH too far, the .2 puts it almost neutral.
View attachment 378598
If you have to all of this for minimal benifits, its not worth it n even than its still shit,
Take your 2 post "dislike" and put it up your A**, I haven't racked up enough dislikes in my meso career anyways, so , thanks!
People dont know how to articulate research n are slow so they downvote you thinking they know more LOL.
I mean with 5mg copper orally you will puke, same with zinc, injecting minerals that the body is this sensitive with it makes sense it would cause a reaction. usually happends when taking something really acidic and dont have enough stomach acid

Dident seem like copper have low ph tho from what i could find, tought it would be suuper low

Think it was around 5 so its hard to say if the sting is from the coppers ph or just copper itself

But interesting thing about the free copper ions. the ghk got jano analyzes but stuff like that he cant see
Bro please stop making post related to GHK-CU im begging you,
You get away with spreading misinformation too much n no one calls it out
No benefits? GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration - PMC

Were you mega dosing caffeine while running it? 300mg a day

Caffeine is shown to block collagen supplement to work
Like bro stop it, I already debunked every claim in the other thread and you ignored it. everyone save y'all selves from time. I genuinely don't know how you've been on a forum for 10+ years jus spout nonsense like this
 
Look everyone, Nard said it so therefore it MUST be fact. His stance is 100% undeniable and is w/o question the ONLY correct answer. His anecdotal evidence involving a trial of exactly 1 is far more credible than your data collected in the exact same manner. /sarcasm

Look man, even if you are right (which you're not based on my personal experience along with several dozen people who I personally know first-hand in RL and only 1 had no response) you're a douche.

I tried to give you the benefit of the doubt from your previous needlessly aggressive posts but I can tell that's just how you roll... everything is an ePeen contest.

I'm new here and I can already tell that my experience here will be made instantly better by adding you to my ignore list.
 
Look everyone, Nard said it so therefore it MUST be fact. His stance is 100% undeniable and is w/o question the ONLY correct answer. His anecdotal evidence involving a trial of exactly 1 is far more credible than your data collected in the exact same manner. /sarcasm

Look man, even if you are right (which you're not based on my personal experience along with several dozen people who I personally know first-hand in RL and only 1 had no response) you're a douche.

I tried to give you the benefit of the doubt from your previous needlessly aggressive posts but I can tell that's just how you roll... everything is an ePeen contest.

I'm new here and I can already tell that my experience here will be made instantly better by adding you to my ignore list.
Bro,
I stopped reading after you rambled about zinc LMFAO.

But let me give you the benifit of the doubt and not speak anecdotally and lets cover theoretical mechanism regarding this molecule/chemical.
GHK-Cu for decades say that it was probably about 90/10 with the 10% being those who don't have ISR.
Based on what trial ? what outcome metric ? what dose ? what end point ? Published where ?
There is no human clinical data linking GHK-CU injection to ISR correction nor is there even a fucking standarizerd clinical biomarker for "having ISR" had to LOL at that part.

When injecting GHK-Cu sub-q it's imperative that you have proper zinc levels in your system as well. Preferably before starting GHK-Cu injections. Do you take a ZMA supplement?
Lets use some math here since I dont even think you understand how a chemical copper attachment converts to mg in a human.
Source: PubChem (CID: 161323)

GHK-CU is a 1:1 complex:
1 molecule GHK = 340g/mol
1 copper ion (Cu+2) = 63.5g/mol
For a total 403g/mol
So copper makes up 15.7% of the weight here
Screenshot 2026-02-11 at 3.24.16 PM.webp
Now lets say your doing a daily injection of 2mg for example
2mg + 0.157 =2.157 mg 0.314mg of copper
Basically 314 micrograms of copper
Source:

Based on the Tolerable Upper intake Level the (UGL)
is 10mg a day in adults, (Which is no where near what GHK contains LMFAO) which is far below UL
Let me even be generous and nice here and say your taking 5mg of GHK-Cu, that still fucking below the UL limit.
So claims like:
add proper zinc into your system to oppose the additional copper first.
Are fucking comical to me n shows me you have 0 understanding of chemistry, unit conversion and pharmacology.
On top of the Zinc deficiency is rare in healthy adults in developed countries especially if your not vegan.

Even after giving you the benefit of the doubt, this doesn't even take into account the Bac water and PH balance when mixed with the peptide.
But to dumb it down for you since you need it:

When mixed with Bac water, due to the PH balance with copper, the complex partially falls apart which means (free coper ions locally)
which = sting/ PIP irratation meaning its not doing fuck for skin LMFAO

But again let me give you the even more of the benifit of doubt and assume the copper is intact, copper is required for Lysl oxidase -> collagen cross linking, but here is the part most people miss, that enzyme is already functionally normal in healthy adults unless your copper deificnet, so adding more copper doesnt linearly increase Lyme activity since there already saturated due to the body's homeostatic buffering.

TDLR;
In copper sufficient healthy adults(Majority of adults), collagen production is not limited by copper availability, so systemic GHK-Cu is unlikely to produce meaningful aesthetic improvements beyond wound healing. Its placebo if anyone reports skin glowing claims n scams you

I just single Handedly Eviscerated your post using science and not annecdotes. Have a good day
 
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There are human studies in ghk-cu, so we know that works. Injectable is another matter.
On topical use yes you are right,

But sub-q ? the reason it never went into clinical human paper, is cause even the PHD researcher's knew it was a waste of time and money mechanistically. its not doing anything better than what we already have on the market.

n id only say topical is worth it after micro needle session,

But Taz/Trent are going to do far more for your skin overall
 
ghk-cu doesn’t have enough copper in it to require zinc supplementation to counteract the copper. That’s not even bro science, that is some made up Reddit shit that someone posted and then the tards there ran with it
 

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