MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
I would run 2.5mg Pharma Mounjaro alone first, pharma one is usually stronger given the reports
Been cruising on Tirz at 7.5 mg/week for the past two months - smooth ride. Got my labs back: A1c at 4.9, glucose 74, insulin 7. Running 3.2iu of HGH every night like it’s part of my damn sleep hygiene. Thinking about bumping Tirz to 10 mg next month - can’t just let it sit there in the fridge like a forgotten ex.
Bloods came back clean - liver’s chillin’, pancreas ain’t panicking, and I’m still prettier than last month.
Bloods came back clean - liver’s chillin’, pancreas ain’t panicking, and I’m still prettier than last month.
Ghoul
Member
If you do be prepared for a potentially stronger effect. Not huge, but a little more than you're accustomed to now at 10mg UGL:
explodingHeart
Member
I tried filtering some chinese peps. I reconstituted carefully and wasted 3 of the cheaper $1 Chinese .22 micro filters on an semaglutide vial. Could only get about 10mg through it without clogging it up. The post filtered solution was much more clear.
Is that to be expected?
Was there ever a conclusion on the injecting IM / SubQ for lessened immune response?
poolshockguy
New Member
Sema is rougher than tirz . And the pharma grade is better than ugl. Maybe give yourself 2.5 tirz for 1st week to see how you do. Then go up every week since your body should be used to the higher dose already.
Trenbolonetax
Member
Yes, IM would be best to avoid that of the two options.
How are you guys getting past the GI upset? I pretty much shit liquid for a few days after my dose. I heard that psyllium husk works but I am taking in like 55g of fiber a day so I’m not sure a little fiber pill is going to actually put a dent into it. It’s not a big deal (as I can still function and I just hydrate more) but it’s annoying as hell.
I had this on the first week of Tirza but simply added a ton of veggies and since then my stool is incredibly. I call it the "King-poop" basically i only need to wipe once even. Tirza saved me so much ass-wiping time and improved my stool. Really just gotta have the veggies covered. I have about 250g of Veggies with every meal and a little spoon of fiber with my last meal in the evening
Ghoul
Member
Get loparamide 2mg tabs (aka immodium). 2 tabs after the first incident of diarrhea, 1 more after each subsequent one. Usually less than 10 total will completely resolve it. Don't take it lightly, because dehydration can accumulate and leave you in bad shape. If you're ordering Indian PCT meds, "Roku" is an excellent form of loparamide (faster acting capsules vs the solid tabs in most stores). and dirt cheap so buy a bunch to have on hand.
I eat so many peas it’s ridiculous haha. Peas, oats, and oranges make up most of my fiber. But I’ll try and add some more and grab some Imodium at ghouls mention. Thanks guys
Ghoul
Member
No that shouldn't be happening. What size is the filter? 13mm?
Assuming there isn't something really wrong with the filter (it is sterile .22um PES right?), there are only a couple of possibilities.
The peptide isn't fully dissolving, fouling the filter. How much BAC and what type?
There is severe aggregation, which is fouling the filter.
I've had a couple of batches of different peptides that did this, forcing me to use a 25mm filter, which has 5x the capacity of 13mm before clogging, while other batches of the same peptide were easily filtered with a single 13mm filter. Usually the batches that clogged the filter had some visible particulate when looked at through light, or, tiny "gel" looking spots on the vial wall, both of which are signs of aggregation.
explodingHeart
Member
This one I probably fucked up. I let the vacuum pull out the full force of bacteriostatic water using a 22 gauge needle. The end result was cloudy.
My goal was to dilllute 30mg of semaglutide into a sterile 30ml vial.
Bacteriostatic water was from 10ml packs of "sterile water for injection", BA was USP grade from an online lab supply store.
Using cheap $1 chinese PES 25mm 0.22um filters.
I'll retest. I have Plenty of QSC 24 iu GH and 50mg tirz.
I'll filter each into a sterile vial and carefully reconstitute. I'll filter the tirz first, GH last. I'll use the GH up within 3 days so no big deal if it forms some aggregates mixing with the Tirz.
Does this sound correct?
Full disclaimer: I've YOLO'd cloudly GLPs before and was careless as hell about injecting peps. I've never had an infection or serious injury in my entire life so I've gotten really complacent in my old age.
Ghoul
Member
30mg Sema? How much BAC were you able to get in that vial to reconstitute?
The filters were doing their job, they got clogged by aggregates from what was probobly an insanely over concentrated solution.
What you could have done was transfer to a larger vial, add more BAC, and left it overnight, then filtered it. When you dilute a peptide that's formed aggregates, some may be reversible and can separate back into monomers when the concentration is reduced.
Last edited:
explodingHeart
Member
Filled one sterile 30ml vial with BAC. Then using a 10ml syringe, I violently washed out the tiny 3ml 30mg sema vial with BAC and injected it into the 30ml vial.
Then attempted to violently fill another sterile 30ml via syringe filter. So now I have a cloudly 30ml vial and and about 10ml filled of a very clear 30ml vial.
Had absolutely no idea. I'll probably do that with Tirz first, which is not cloudy and I was much more careful with.
Thanks for all the info on aggregates!
Ghoul
Member
We're prohibited by the rules from discussing UGL sources outside of the Underground forum.
Create a new post there and while you'll get some unhelpful comments, you will get some useful opinions as well.
Thank you for letting me know. I need to reread the rules and dig further. Appreciated.
