GLP difference

Here2Learn

Member
TLDR:
No GLP+ working out +tracking food=no WL 1 year
GLP+low calories=very small WL Oct 1- Oct 15 .8lb loss
GLP+more food+weight training=fast WL Oct 15-30 4.8lb loss


I used to workout all the time, then went undiagnosed with scarlet fever for a couple of years and almost died. It’s been 24 years and I still don’t feel like my body has fully recovered.

Couple years ago I got back into weight training and tracking all of my food. I felt good but the scale would go up and down 5lbs and I never lost weight. My inflammation was so high and never got relief. Stuck with it for a year and then we had a big cross country move and I didn’t get things going again.

Now I started taking Sema the end of April which really helped my inflammation so my joint pain was a lot better. I was exhausted on it all the time though, non function barely getting through work. Scale moved but very slowly. Switch to Tirz and felt a lot better so I started lifting weights again, tracking food and all just the way I had before. On just Tirz the scale moved slowly. Adding in the workouts and the extra food the scale has really been moving.

I’ve enjoyed learning and tracking my data points. I have some healing peptides in the mail and hope to get some more long term things addressed.
 
Also, had been dosing Reta .5mg for boost to energy.

Have no real appetite suppression or GI issues.

When you look at the Tirz trials, as weekly doses are titrated up, 2.5-5-7.5-10-12.5-15, the number of "non responders" shrinks. There's a big drop off around 7.5, and by 15mg there are nearly no non responders, less than 1%.

The appetite suppression effects appear dependent on the total proportion of GLP receptors agonized. Everyone has a different amount, men having more dense concentrations, and larger body mass typically having more. But much of this is also based on genetics.

So don't lose heart over your non response. 7.5 would be the next stop after 5 on the pharma protocol. Since 4 is ineffective, I'd go straight to 7.5. There's no risk of getting severe sides with this jump, Tirz is so much more mild than Sema. If you still feel nothing after TWO weeks, two doses, go to 10mg. It's almost certain you'll find that dose effective.. After plateauing, to lose more, titrate to 12.5, then 15 if necessary.

I'd avoid stacking, try to stick to once a week dosing, and only after failing to respond at 15mg would I change the plan.
 
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When you look at the Tirz trials, as weekly doses are titrated up, 2.5-5-7.5-10-12.5-15, the number of "non responders" shrinks. There's a big drop off around 7.5, and by 15mg there are nearly no non responders, less than 1%.

The appetite suppression effects appear dependent on the total proportion of GLP receptors agonized. Everyone has a different amount, men having more dense concentrations, and larger body mass typically having more. But much of this is also based on genetics.

So don't lose heart over your non response. 7.5 would be the next stop after 5 on the pharma protocol. Since 4 is ineffective, I'd go straight to 7.5. There's no risk of getting severe sides with this jump, Tirz is so much more mild than Sema. If you still feel nothing after TWO weeks, two doses, go to 10mg. It's almost certain you'll find that dose effective.. After plateauing, to lose more, titrate to 12.5, then 15 if necessary.

I'd avoid stacking, try to stick to once a week dosing, and only after failing to respond at 15mg would I change the plan.
I don’t feel like I need to go up right now as I am losing. Yea I don’t get appetite suppression but honestly that isn’t a huge deal for me. Seems like it is working at 4mg being the scale is moving. I personally would prefer to keep my hunger to build my habits on normal living.
 
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