In my last post, Joe Schmoe recommended initiating HCG therapy the same day as my last Test shot. I am curious as to the rationale behind this mode of administration. From the journal articles that I have reviewed, serum HCG peak in 84 hours with serum testosterone levels reaching peak in 234 hours (Trinchard-Lugan, Reproductive Biomedicine; January 2002). Peak serum testosterone levels after a IM 200mg/ml of Testosterone cypionate are reached 5 days later with basal levels being obtained approx. 14 days after administration (Nakin, Fertil Steril; 1987). Why wouldn't I wait two weeks to start HCG therapy if the ultimate goal is stimulate the Leydig cells to start production of Test and return the testes to original size. Simutaneous adminstration of both could potentially bring test/estradiol levels too high and result in adverse effects. More importantly, artificially elevated T levels from the injection would still be affecting the HPTA and thus would not facilitate the return to normal function. I understand that use of HCG is still an artificial means to elevate natural T production, but returning the testes to their original size and ultimately their full productive capacity is my goal. Clomid or Nolvadex therapy (for LH stimulation and antiestrogenic function) to close my ancillary therapy of course.
