So, I have a guy. He is extremely serious about his diet and training. He goes to a TRT clinic (to run his labs) but I "supplement" his program. He was on their test, but now gets it much more cheaply. He is also on GH and his wife is on Zepbound. Lets just say he gets everything via this forum for about 10% what it would cost if he got it from the pharmacy/clinic. He trusts me and is excellent to work with. I want to help him as much as possible.
He is 53 and running 250 test and 150 deca/week with 3iu's of GH (from sources like Opti/Lobster/Sigma....all with excellent Janoshick results) 5 days a wek. His wife has been running Sigma sourced Zepbound, 5mg and has lost 23 lbs. He has been running everything for more than 12 weeks, except at week 8 swapped out the deca for Primobolin, 200 mgs/week.
He got labs. Most everything good, within range. His total test came back at 1350 (top of range 1100, so not a big deal) however his IGF-1 was just slightly above mid range. My advice would be to go 4 iu's maybe a touch more since he is not a good responder to GH (3 iu's 5 days a week puts me over the top of my range). His body/physique has improved dramatically in those 12 weeks.
However, he has suddenly developed pretty severe water retention in his lower leg. It presents like peripheral edema. I asked if he were diabetic and he said no. Nonetheless I am suggesting he get A01c labs.
It might also be a Kidney issue.
Since his IGF-1 was moderate I don't think the GH is causing the water retention....plus he was on it for 12 weeks before the water retention problem.
Since I was baffled, I told him to see a general practitioner (MD) who could diagnose the problem (and then maybe a specialist). However I also told him that most doctors are completely ignorant when it comes to HRT, so to just make sure his numbers stayed w/ in range. Then again maybe he should go off the GH and Primo and just do minimal TRT?
Any idea as to what might be going on is greatly appreciated. As mentioned, he might need to get some kidney labs.
He is 53 and running 250 test and 150 deca/week with 3iu's of GH (from sources like Opti/Lobster/Sigma....all with excellent Janoshick results) 5 days a wek. His wife has been running Sigma sourced Zepbound, 5mg and has lost 23 lbs. He has been running everything for more than 12 weeks, except at week 8 swapped out the deca for Primobolin, 200 mgs/week.
He got labs. Most everything good, within range. His total test came back at 1350 (top of range 1100, so not a big deal) however his IGF-1 was just slightly above mid range. My advice would be to go 4 iu's maybe a touch more since he is not a good responder to GH (3 iu's 5 days a week puts me over the top of my range). His body/physique has improved dramatically in those 12 weeks.
However, he has suddenly developed pretty severe water retention in his lower leg. It presents like peripheral edema. I asked if he were diabetic and he said no. Nonetheless I am suggesting he get A01c labs.
It might also be a Kidney issue.
Since his IGF-1 was moderate I don't think the GH is causing the water retention....plus he was on it for 12 weeks before the water retention problem.
Since I was baffled, I told him to see a general practitioner (MD) who could diagnose the problem (and then maybe a specialist). However I also told him that most doctors are completely ignorant when it comes to HRT, so to just make sure his numbers stayed w/ in range. Then again maybe he should go off the GH and Primo and just do minimal TRT?
Any idea as to what might be going on is greatly appreciated. As mentioned, he might need to get some kidney labs.
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