hGH with MK677

[Slowww]

Does anybody have experience running the two at the same time?

I will run tren for the first time and have some mk677 in hand in case appetite or sleep becomes a problem. I tried mk677 in the past without AAS it any hGH, & it significantly increased my appetite + sleep quality, but sides were worse than 16iu of hGH (Which resulted in no noticeable sides in terms of quality of life) until dropping the MK677 dose which was not particularly high in the first place.

Did you experience side effects being compounded, Or about the same? Would it be a good idea to reduce hGH use or would mk677’s gh increase be negligible? Did you notice any difference with blood sugar spikes or insulin resistance?

 

[Jin23]

My gyno actually got started on a stupid mk and a test booster run ... Me personally, mk really worsened my anxiety and thus, did not help with sleep. Ghrelin is a "stress" hormone and having high ghrelin signaling all the time imo can lead to a sort of chemically induced ptsd state. Kinda similar to having constant AR and norepinephrine activation from aas use.

But we differ so much, that one might have panic and anxiety attacks on it, while somebody else would be raving how it significantly elevated his quality of life ...

Otherwise using mk with gh was something that leo from leo and longevity was advocating. Primarily for the reasons of having more then one type of GH in your system. GHRP's are effective even in the presence of exogenous GH use.

What would concern me, due to simultaneous tren use, is prolactin control. MK is notorious for elevating prolactin. All ghrp's do it, some more and some less.

If you want better sleep, however, then try using a GHRH (mod grf and cjc1295) not a GHRP. GHRH promotes NREM 3 and NREM 4, especially when used in the second part of the sleep cycle, when REM and shallow sleep is more abundant.

 

[Jin23]

Oh and insulin resistance with MK is supposedly unproportionately worse then, let's say, with GH, when comparing similarly elevated levels of igf1.

 

[Slowww]

My gyno actually got started on a stupid mk and a test booster run ... Me personally, mk really worsened my anxiety and thus, did not help with sleep. Ghrelin is a "stress" hormone and having high ghrelin signaling all the time imo can lead to a sort of chemically induced ptsd state. Kinda similar to having constant AR and norepinephrine activation from aas use.

But we differ so much, that one might have panic and anxiety attacks on it, while somebody else would be raving how it significantly elevated his quality of life ...

Otherwise using mk with gh was something that leo from leo and longevity was advocating. Primarily for the reasons of having more then one type of GH in your system. GHRP's are effective even in the presence of exogenous GH use.

What would concern me, due to simultaneous tren use, is prolactin control. MK is notorious for elevating prolactin. All ghrp's do it, some more and some less.

If you want better sleep, however, then try using a GHRH (mod grf and cjc1295) not a GHRP. GHRH promotes NREM 3 and NREM 4, especially when used in the second part of the sleep cycle, when REM and shallow sleep is more abundant.

Yeah when I first started I was a bit worried about elevated fear responses and anxiety from studies in rats, but i had no experiences of panic attacks or any anxiety while using it, just had some extremely unusual dreams. My big concern was aggravating carpal tunnel or causing numb hands etc.

Are there any studies regarding prolactin increases while using it or is it anecdotal? Last time I did my fair share of reading about it was several years ago, but it’s hard to figure out what is applicable during human consumption at the time.

Thanks for the tip! I’ll look into those peptides.

 

[Jin23]

just had some extremely unusual dreams.

That's probably because of elevated GH. Can't be sure though, as there are other MOA's with a GHRP. GH in it self potentiates REM. If I take GH before sleep, it's like going in to another life (the dreams are so real) and not going to sleep. I just wake up traumatized lol GH is actually pretty bad for sleep as it promotes REM and sleep fragmentation. GHRH is what promotes slow wave sleep. Even if you don't notice a decrease in the quality of sleep while on GH, if you did a sleep study in a clinic, it would Probably show a decrease in SWS and an increase in REM, light sleep and fragmentation, especially in the second part of the night. How bad, that would depend on your baseline quality of sleep.

 

[Jin23]

Honestly, MK0677 is such a "dirty" drug. I personally would stay clear of it. The only real reason to take it is because it's cheap.

You also can't control when your GH spikes, so it's hard avoiding food with the elevated GH. Imo, this is one of the good reasons of using GH, as the increase in somatostatin shut's down your natural GH production, giving you control of when you have elevated GH.

Instead of Mk677, check out GHRH analogues. Specifically CJC-1295, as it's similarly easy to use as mk, due to it's long half life. I don't know, however, how effective they are in the presence of elevated somatostatin levels when using GH and if there are any other mechanism that would decrease it's effectivity while on GH.