A lot of these IG lads are young. 20-35 range. At that age you can get away with things that would make must of us in our 40s shudder. What you're seeing is guys in the prime of their lives abusing large doses of AAS/PEDs.The unknown is how long this can go on for, 5,10,15 years?
The body can handle abuse pretty well when you're younger. That being said i'm sure most have bad days or health issues not discussed on the channel or whatnot. They're to busy posing for the camera or plugging whatever supplement company is paying them. You can see the strain in their faces though..guys huffing and puffing after a set or profusely sweating after a small warm up. It's not sustainable by any measure. Im not sure if some of the IG guys even go to the dr or get bloods done on a regular basis.
It usually comes crashing down in their late 30's-40's when the toll starts to show. Bostin Loyd is a prime example..guy is in kidney failure already and not even 28 years old. Lots of pro's forced into retirement at 25-30 years old due to various health issues.
The major issue beyond the blaring drug use IMHO is Bodyweight. The human body is a complex machine as well all know. One thing it doesn't handle very well is huge fluctuations in weight..be it dropping it to fast or packing it on quickly. The heart, kidneys,joints dont want 20,30,40lbs of additional weight. Its a strain whether its fat or muscle. Muscle even more so as it requires more oxygen and blood to function.
You'll rarely see a YouTuber who was 175lbs naturally and started PEDS bulks up to 205 drop dead. What we do see year in and year out are guys north of 250lbs dropping dead or encountering health issues that either halt their career or training all together. Its been happening in the sport of professional wrestling for decades. Is it the schedule, the drugs, drinking, diet,? I think its a combination of all those factors but more so stress. Stress on the body to be that big, eat that much, handle all the drugs. Something has to give and usually it does.