GRANVILLE said:
After massive long term trials on rats, the repair axis of growth varied very little irrespective of time taken, which leads to the conclusion that it would be adviseable to inject the growth at the least damaging time to ones own body............early a.m.
Granville,
I'm somewhat aware of the natural circadian rhythm of indigenous GH release, but is there evidence of GH suppression? We all know that introducing exogenous testosterone inhibits the bodies' own test production, but is the same actually true for GH? Suppose the body produces 1 IU of GH during sleep and you inject 4 IU at bedtime. What information is there that we would not, in effect, have 5 IU's of GH circulating...an additive effect? I'm not arguing, just making discussion.
-RVZ
RVZ,
Many years ago when I was young and probably more outgoing I had quite a few papers published in the Lancet, but found it was just a platform to put your head on so that someone with a different view can try to chop you down. From there on I went free-lance and now do the research for other people, if they want to publish the results thats up to them, it has been documented elsewhere that exogenous introduction of growth inhibits ones own production, the way I look at it is that the human body is basically lazy and if there is an external source of a hormone, the receptive areas transfer the information and the relevant organ stops production, thats why there would appear to be such a high incidence of diabetes, with the high intake of high glycemic foods the body just gets used to pulsing insulin on a regular basis and inevitabely gets lazy and produces insulin too regularly because the pancreas has been weakened sometimes beyond repair.
As einstein kindly pointed out growth has a very short half life, and I have seen no incidence of supression problems if growth is introduced during the bodies own "low" production times. With experiments on rats if you give them the equivalent of 4ius of growth at night, the total circulating during the night period is 4ius, indicating NO production of growth from their own organs, this probably does no damage short term, but rats given a large exogenous dose of growth at night for more than a month re-programme their own bodies to cope with the situation, and stop or greatly lower their own nightly production even when the exogenous dose is stopped. I have seen several incidences of well known footballers who have shut down their own growth production because of nightly exogenous shots to help heal muscle/tendon damage, as I have mentioned in a different thread, it has been so bad that the clinic where I research forbid any p.m. growth introductions. There are mountains of un-published work on this subject, the clinic has me researching just so they are covered against litigation, the results are for them, and as is common in the commercial world, many institututions don't release information as they feel it will help the competition. This doesn't help the world in general, but thats one of the results of greed. sorry I digress, from the extensive long term research I have done on rats, and from what I have seen with treated "subjects" it is 100% confirmed that long term exogenous introduction of growth at night, WILL in every case limit or completely shut down the subjects own nightly pulse of growth. I am taking this one stage further, I have for a long time thought that old people sleep during the day in the bodies attempt to replicate the larger pulse of growth produced at night, during the day also, if they are given 1iu of growth in the morning they dont nap during the day, same thing at night and they still take naps. Being honest one of the beneficial sides of long term growth for me is that I dont react quickly to critisism and enjoy debating, so keep it coming lol