IGF baseline- does it matter

hotdog23

New Member
Ok the endocrine system operates on a negative feedback loop. GH levels, IGF levels, somatostatin, ghrh, ghrelin (and other mechanisms) are all connected.

So why does an IGF baseline matter? Testosterone base values have ZERO impact on TT levels while exogenous hormone is administered. I believe the same is true for IGF levels. Whatever your prior levels were mean next to nil while supplementing synthetic hgh - as your natural production will be next to nil while supplementing.

---> when IGF is upwards of 400, somatostatin will not be inhibited, ghrh will not be released. Why would it?

Maybe I'm wrong. I commonly hear ppl requesting baseline when determining IGF results, but the only thing I think it could show is a level of sensitivity to GH maybe
 
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