Initial Blood Test - Feedback Welcome

[BigPoppaNasty]

Male, 35 6ft (5’11) 224lbs

Hone Health Initial Screening Results


Been training consistently since 2012 (lifting + BJJ). Recently did a full blood panel through Hone Health as an initial screening to see where I’m at. This was a fasted draw, a dehydrated, and done post upper-body workout.


Bloodwork

Hormones

• Total Testosterone: 433 ng/dL
• Free Testosterone: 12.7 ng/dL (calculated)
• SHBG: 18 nmol/L
• Estradiol (E2): 25 pg/mL
• LH: 4.3 mIU/mL
• PSA: 0.67 ng/mL
• Albumin: 4.6 g/dL
• TSH: 2.16 mIU/L
• Free T3: 3.1 pg/mL
• T3 Uptake: 32%
• Total T4: 8.0 mcg/dL
• Free T4 Index (T7): 2.6

CBC & Hematology

• WBC: 5.7
• RBC: 5.69 M/uL
• Hemoglobin: 16.9 g/dL
• Hematocrit: 50.7% (slightly high)
• Platelets: 255 K/uL

Liver/Kidney Panel

• AST: 26 U/L
• ALT: 31 U/L
• Alkaline Phosphatase: 75 U/L
• Total Protein: 7.3 g/dL
• Albumin/Globulin Ratio: 1.7
• Bilirubin, Total: 1.9 mg/dL (high)
• Creatinine: 1.13 mg/dL
• eGFR: 87 mL/min

Lipids

• Total Cholesterol: 156 mg/dL
• HDL: 34 mg/dL (low)
• LDL: 96 mg/dL
• Triglycerides: 160 mg/dL (high)
• Non-HDL Cholesterol: 122 mg/dL
• ApoB: 92 (high)

Hone Health Feedback

• Doctor noted bilirubin at 1.9 and suggested it could be benign Gilbert’s syndrome since my AST, ALT, and Alk Phos are normal.
• Lipids were flagged: low HDL, high triglycerides, elevated ApoB.
• They did not recommend TRT at this time since T = 433 and Free T = 12.7 weren’t considered clinically low and I reported libido/sex drive.

What They Prescribed

• Anastrozole (1 mg weekly) – Aromatase inhibitor to lower estrogen
• Tadalafil (5 mg daily, up to 20 mg on demand) – for sexual health / blood flow

Posting here for community feedback on my bloodwork, curious what you all think of these results and the treatment plan(not planning to take it). On paper, my E2 doesn’t look high (25 pg/mL), so I was surprised they suggested an AI right out of the gate.

 

[BigDadd7]

Your test is definitely low. If you want trt, 100mg/week is a classic starting point. Retest after 4-5 weeks. Your e2 is fine. I have no idea why they would recommend an ai. That seems nuts to me. Your hematocrit and bili may be due to being a little dehydrated. Get that water in and retest in a month. Cialis is fun. If you don't need it right now, bank it away for a future date- it can make for a fun getaway weekend, or even a great friday night when you want to take her to pound town.

 

[ShutUpAndPump]

E2 not high, test a little low, prolactin is missing.
Here it all depends on whether these levels give you problems or you're fine

 

[sionnach]

No BJJ comp org currently does testing (a couple say they do) so everyone at the top is on massive amounts of juice. Are you interested in competing?

At 35 you could go either way with the PEDs. If you're still rolling at 40 you'll probably want some though. What's your plan?

Edit: like Daddy said, i'd skip the AI. Take the Cialis though, lots of benefits.

 

[BigPoppaNasty]

E2 not high, test a little low, prolactin is missing.
Here it all depends on whether these levels give you problems or you're fine

For the most part, I have a high sex drive, yet am
Fatigued and motivation is low at times (discipline keeps me going) I am unsure if that just from starting the day at 5am / and daily life or low T

No BJJ comp org currently does testing (a couple say they do) so everyone at the top is on massive amounts of juice. Are you interested in competing?

At 35 you could go either way with the PEDs. If you're still rolling at 40 you'll probably want some though. What's your plan?

Edit: like Daddy said, i'd skip the AI. Take the Cialis though, lots of benefits.

Yea during my younger years I competed a bunch, now going on 8 years I'm not looking to compete as much. I plan to lift and do BJJ as long as my body allows.

Honestly my thoughts are to be optimized and able to be active for my kids. Not going to lie, also truthfully vanity. Want to look like I lift after all these years doing it. ( posted photos in my new guy intro )

 

[sionnach]

Between the kids (good reason btw), the gym, and the mat, you'll feel better running TRT/cruise at 1000-1200, which is pretty much the consensus target among my pajamahugging bros. You can go higher later on down the road if you want but if you decide to jump on give that several months.

The downside is you'll have to stay on top of your bloodwork, and it'll likely be forever. At 35 you have time to think seriously on it though.

 

[BigPoppaNasty]

pajamahugging bros.

Sorry, I'm a filthy no-gi broham.

The downside is you'll have to stay on top of your bloodwork, and it'll likely be forever. At 35 you have time to think seriously on it though.

Yes, this is something I have considered for years and still want to gather more knowledge prior to making any decisions.

 

[RockyP]

at 5'11' 225 i'd be curious if you have sleep apnea - have you ever had a sleep study? I know you said the labs were dehydrated but it's important to rule out OSA especially if you plan to use TRT / PED's. untreated OSA comes with a host of shitty health effects and will raise your HCT levels.

Please excuse me for saying it, but the medical providers you are working with are idiotic. You absolutely positively do not need anastrazole. The only thing that will do is make your joints hurt, worsen your lipids, and likely kill your libido even more. And you are symptomatically hypogondal. There are lots of HRT docs who will treat you based on your symptoms and not your labs. Test less than 500 with symptoms as your report warrants treatment.

Those lipids aren't great either. How is your diet? Does high cholesterol run in the family? I would get that taken care of prior to using any testosterone (consider a statin - either rosuvastatin or pitavastatin). Your HDL is only going to drop more on test / PEDs, and you want that LDL under 70 especially given the low baseline HDL. I'm speaking from experience since I have genetically low HDL and keep my LDL as low as possible.

I think you would benefit greatly in terms of quality of life from some test replacement, 100 - 150 mg weekly. no AI is needed at those doses and def not now.

Agree with the brothers re: Cialis. Every man on test / PEDs should take it. vasodilation and endothelial protection.

 

[sionnach]

Sorry, I'm a filthy no-gi broham

Based

 

[BigPoppaNasty]

at 5'11' 225 i'd be curious if you have sleep apnea - have you ever had a sleep study? I know you said the labs were dehydrated but it's important to rule out OSA especially if you plan to use TRT / PED's. untreated OSA comes with a host of shitty health effects and will raise your HCT levels.

My wife and friends have both noted my snoring and have suggested I should get tested for sleep apnea. Just gotta buckle down and get it done honestly.

Please excuse me for saying it, but the medical providers you are working with are idiotic. You absolutely positively do not need anastrazole. The only thing that will do is make your joints hurt, worsen your lipids, and likely kill your libido even more. And you are symptomatically hypogondal. There are lots of HRT docs who will treat you based on your symptoms and not your labs. Test less than 500 with symptoms as your report warrants treatment.

Those lipids aren't great either. How is your diet? Does high cholesterol run in the family? I would get that taken care of prior to using any testosterone (consider a statin - either rosuvastatin or pitavastatin). Your HDL is only going to drop more on test / PEDs, and you want that LDL under 70 especially given the low baseline HDL. I'm speaking from experience since I have genetically low HDL and keep my LDL as low as possible.

Thank you for the in-depth response, I also was confused why they mentioned “anastrazole”. I took the consult visit just to see what they would say not to just jump on with them and their direction

Diet wise, I definitely could eat cleaner and working on the that currently with this cut. Currently down to 224lbs from 250lbs

I think you would benefit greatly in terms of quality of life from some test replacement, 100 - 150 mg weekly. no AI is needed at those doses and def not now.

Agree with the brothers re: Cialis. Every man on test / PEDs should take it. vasodilation and endothelial protection.

Good to know and thank you!

 

[BigPoppaNasty]

at 5'11' 225 i'd be curious if you have sleep apnea - have you ever had a sleep study? I know you said the labs were dehydrated but it's important to rule out OSA especially if you plan to use TRT / PED's. untreated OSA comes with a host of shitty health effects and will raise your HCT levels.

Appreciate this was a kick in that ass that after years triggered me to go to the Dr and finally get checked. Confirmed Severe Sleep Apnea, start using a CPAP this week and will recheck bloods.

 

[RockyP]

Appreciate this was a kick in that ass that after years triggered me to go to the Dr and finally get checked. Confirmed Severe Sleep Apnea, start using a CPAP this week and will recheck bloods.

Great to hear it brother. My sleep med doc said up to 6 months before the HcT impact of osa normalizes. But you’ll start feeling better from an energy standpoint very soon (and start reversing all the other health issues from osa). I can’t sleep without mine now.

 

[BigPoppaNasty]

Great to hear it brother. My sleep med doc said up to 6 months before the HcT impact of osa normalizes. But you’ll start feeling better from an energy standpoint very soon (and start reversing all the other health issues from osa). I can’t sleep without mine now.

Yes, very excited to see the change.