Janoshik HGH Dimers worth it?

[Ghoul]

I appreciate your thoughts on this. If people are still having success with HGH and filtering (ie it’s not destabilizing the product), I will 100% start filtering it.

It's not destabilizing it. In order for that to happen, the rHGH monomer would have to be denatured.

Basically, a peptide is a chain of amino acids, AND a specific folded shape. If that shape is unfolded, aka denatured, the peptide loses effectiveness and it will cause aggregation by exposing "sticky" parts of the chain that other molecules can stick to. This unfolding was the hypothetical damage that was theorized to potentially occur with syringe filtering because when pharma filters peptides with industrial machinery, if the pressure is too high, it will cause this to happen.

rHGH was analyzed before and after syringe filtration, and there was no denaturing that occurred. The test was so tightly controlled they used a machine to simulate the maximum pressure a human would apply to a syringe.

One thing to keep in mind though, is that the main cause of aggregation is the formulation. If there aren't ingredients to control PH for instance (called buffers, which all pharma and some UGL rHGH has, and other UGLs don't use), aggregates can reform after a certain amount of time.

Because of that, it's best to filter just before use, and try to use smaller dosed vials when practical that won't be sitting around for long since time after reconstitution is a factor.

These guideline really apply to all peptides.

 

[Ateam2023]

so reusing a ultra spec vial after filtering hgh is not recommended ? I couldn't find anything useful on that,,

 

[powdered_toast_man]

In theory, the worst case scenario is that your rHGH and the vial are immaculately made and free of contamination, formulation is as stable as Pfizer, etc, and filtering is a waste of time,

There were questions about filtering possibly damaging rHGH, causing aggregation, shedding fibers increasing the amount of particulates, significant loss of rHGH in the filter, etc. In other words, did filtering do more harm than good.

TLDR, these have been studied and the answer is no, There's only upside to filtering. Risk reduction.

Is someone stupid for not filtering? Like I said, it's a matter of risk tolerance. I'm sure there are plenty of experts who'd say I'm an idiot taking unnecessary risks with my health by injecting UGL anything, filtered or not, which is not unreasonable. It's a matter of what the individual decides is a worthwhile risk to benefit ratio. I see filtering as tipping the balance a little more in favor of benefit by reducing risk.

you're nearly convincing me to waste even more of my precious time. damn you! j/k

 

[AlexDavis43]

Do people really filter UGL HGH? I’ve read people say it makes the product unstable. I haven’t seen that tested. But are people filtering and getting good results?

I don't know anyone who filters UGL HGH, and plenty who use it unfiltered with good results.

People have been using non-filtered hGH since forever with no problems.

 

[Spaceman Spiff]

I don't know anyone who filters UGL HGH, and plenty who use it unfiltered with good results.

People have been using non-filtered hGH since forever with no problems.

Not me. The aggregates finally got me. I'm in hospice.

 

[MissedArmDay66]

Do people really filter UGL HGH? I’ve read people say it makes the product unstable. I haven’t seen that tested. But are people filtering and getting good results?

I filter mine and a few weeks ago my igf1 was 447. I don’t think the filtering has had a negative impact lol

 

[Jkeepdrop739]

I filter mine and a few weeks ago my igf1 was 447. I don’t think the filtering has had a negative impact lol

Curious - how many IUs per day? And when?

 

[MissedArmDay66]

Curious - how many IUs per day? And when?

2iu when i wake up