L Carn

Michaelangelo

New Member
Has anyone used injectable L Carnitine?

As a first time user I ordered 1000mg / ml and this stuff is super thick .

I can only draw with a 18g needle and when I inject with a 25g needle ( 50 cc @ 500mg) it takes both thumbs to push it through and prob around 45- 60 seconds .

Also I put some on my finger to rub and it feels like lube and after awhile it gets sticky like honey .

I store it in the fridge also and I let it sit out and nothing changed. I messaged the supplier SSA and they assured me that it’s good to go and very normal . I sent them videos and they confirmed it’s due to the high concentration.

Chatgtp says that according to all my information above that it was more than likely mixed with glycerol and should feel like water by touch and never sticky . And if it’s mixed with oil or glycerol to absolutely not inject it . It also stated you should be able to draw it with a 25g needle although it would be slow .

I bought a whole kit and don’t want to waste it , I’m just looking for someone that can co-sign that they use this protect . Reddit and Google are dead ends and chatgtp say it’s a no go .

Thanks !! I appreciate yall.
View attachment 340489
 
Can you give me more insight on how that relates as Im learning about all this .

ALT=25
AST=19
Not sure if it matters but I'm on a caloric deficit and losing weight . I know that can affect certain readings not sure on these though.

Your lab values are good, so u don't need to inject alot.
Glut helps with liver values alot.

If you have lipid issues you might be better off injecting more L-Carni instead..

e.g
 
Yep, pretty sure its those exact ones. Thats awesome man, glad its working for you at that injection site.


Yeah man idk what this post you linked is on about. I used to go to a clinic for my TRT shots years ago and they were the ones who introduced me to multi-dose spikes. And sure enough, they were drawing my test out of a vial with a spike. Super sterile clinic too. Been using it for years myself now as well in my home. All sorts of oils.
Cool I just hit the order button.
I think he's asking since Glutathione is used to detox the liver, so he was curious about your liver values. Though, GGT is a much better test indicator of liver health.

Some other unsolicited advice since I recall you saying you're health oriented and have familial history of cardiac problems. I would highly recommend getting your lipids. Add on Apo B testing as well. Your Apo B and LDL scores will give you a general view of whether or not you're laying down plaque in your arteries and have signs of atherosclerosis. You're at that age too, to be needing to worry about this for preventive cardiac care. Fixes are relatively easy, statins, ezetimibe, cardio, etc but you want to bring those numbers down, well within normal reference and even below. Easy to source if you've been sourcing your peptides off here. I'm on gear but also very big on health and longevity.
My panel said my numbers are normal and chatgtp said "AST:ALT ratio for you is 0.76 (ALT is slightly higher, which is common in healthy people)."
 
Your lab values are good, so u don't need to inject alot.
Glut helps with liver values alot.

If you have lipid issues you might be better off injecting more L-Carni instead..

e.g
So do you think my initial research and dosing protocol of 200mg 3xweek ( 600 mg a week ) is good ?
 
So do you think my initial research and dosing protocol of 200mg 3xweek ( 600 mg a week ) is good ?

I'm injecting 700mg of glut daily and ur values are better than mine lol.

Glut clears the body rapidly, like an hour or so and it's gone.
Most people do EOD.

I think 200 is probably fine with you, you could make a more concentrated solution then mix it with L-Carni in the same syringe
 
I'm injecting 700mg of glut daily and ur values are better than mine lol.

Glut clears the body rapidly, like an hour or so and it's gone.
Most people do EOD.

I think 200 is probably fine with you, you could make a more concentrated solution then mix it with L-Carni in the same syringe
I planned on takin it after workout but Ill mix it with the Carn and do it pre . Less stabbing the better lol . Thanks for the insight.
 
Diluted my Lcarn with BAC and life is good lol. Just filled up my syringe with 500mg (50 units ) and topped off the rest with BAC. 1ml total of fluid . No soreness at all and it took no longer than 15-20 seconds to inject .
 
Mannnnnn I appreciate your response. I used it once and CHATGTP is calling me an idiot for even considering it lol.

I couldnt draw it with my 25g so I got a 18g to draw it and swapped tips to the 25g. I could inject it but it is super slow. I hate needles and never done IM . As soon as I was done i got light headed for 30 seconds or so I dont want to go with the 18g to inject . Its a mental thing for me.

I found a video that was awesome and I injected in the thigh with no pain at all. BUT the slow injection had me so worried and I was like " is it supposed to be like this? " .

Did you watch the attached video , is yours sticky after awhile ?
I went to the gym with no issues and had no crazy pain just the normal soreness Ive read about.

Thanks for the tips on multi spike and ventro-glutes . Ill go look at that now .

EDIT: Multi Spike is a game changer !!
So, I have their 500/mL and got dayum it seems almost as thick as my husband’s testC.
Also, got about a 5 minute head rush after my first pin- dorsal gluteal. Got all nauseated and everything, real weird. I’m not squeamish at all and don’t usually trip about my own injections.. Wasn’t so bad after my second one- ventral gluteal. No dizziness or nausea but soreness was unbelievable.
All that aside- Im still gonna run it and maybe it’s just mental but I do “feel” like its helping

If you don’t want to shop amazon/big stores theres a few supply vendors on TG that have good prices. One in particular has vial spikes we swear by.
 
The smaller the bore of the syringe, the more push power it will have, because of Pascal’s principal: a 1ml syringe will be able to push thicker stuff through smaller needles with much less force on theplunger than a 3ml syringe, for example. I buy 1cc syringes with 25g needles for drawing, then switch to a 27g 1.25” needle for IM, or a 30g 1/2” needle for subQ. For REALLY thick stuff I’ll draw with an 18g then switch to the smaller needle for actual pinning.


That being said
 
It sounds like you went sub-q for your injection so expect a lump/nodule that'll last weeks lol. I sub-q L carn once and will never do so again. It's a lot less pip but the nodules will start to stack up if you plan on injecting daily. Learn to identify where your ventro glutes are for IM and you'll never go back to anything else.
I'm using the 600mg/ml l-carn subq. I inject 1ml daily. Nodules did sometimes randomly appear, but to fix that, I just massage the injection site (you can feel the bulge post injection) and massage it to help it disburse. Since doing that, I dont get nodules or bumps from these. Also quite painless.

Went to daily injections specifically because I read that it's more like creatine where you need to build up levels and keep them leveled off, so I time it with my creatine which I mix in juice to help get an insulin spike to help deliver both the creatine and the l-carn where it needs to go.
 
I'm using the 600mg/ml l-carn subq. I inject 1ml daily. Nodules did sometimes randomly appear, but to fix that, I just massage the injection site (you can feel the bulge post injection) and massage it to help it disburse. Since doing that, I dont get nodules or bumps from these. Also quite painless.

Went to daily injections specifically because I read that it's more like creatine where you need to build up levels and keep them leveled off, so I time it with my creatine which I mix in juice to help get an insulin spike to help deliver both the creatine and the l-carn where it needs to go.
600mg/ml L-carn is too hypertonic to be used SubQ, you really need it to be in a muscle, and even then it's better if you add back water to dilute it as much as possible - fill up your 3ml if youre using one

Why tonicity matters

  • Subcutaneous tissue is less vascular than muscle, so fluids stay longer in the interstitial space. Hypertonic or hypotonic solutions can draw water in or out of cells, leading to pain, edema, or even tissue necrosis.
  • Muscle tissue is more vascular, so it clears solutes faster than SC tissue. That means IM can tolerate slightly more variation in osmolality, but only within reason.
 
Diluted my Lcarn with BAC and life is good lol. Just filled up my syringe with 500mg (50 units ) and topped off the rest with BAC. 1ml total of fluid . No soreness at all and it took no longer than 15-20 seconds to inject .
The more you can dilute it, the better it will be for your muscles. There arent any pharmaceutical levocarnitines that are more concentrated than 200mg/ml, and even that (Carnitex) is marketed as IV only, because it is so hypertonic. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020182s015lbl.pdf
 
600mg/ml L-carn is too hypertonic to be used SubQ, you really need it to be in a muscle, and even then it's better if you add back water to dilute it as much as possible - fill up your 3ml if youre using one

Why tonicity matters

  • Subcutaneous tissue is less vascular than muscle, so fluids stay longer in the interstitial space. Hypertonic or hypotonic solutions can draw water in or out of cells, leading to pain, edema, or even tissue necrosis.
  • Muscle tissue is more vascular, so it clears solutes faster than SC tissue. That means IM can tolerate slightly more variation in osmolality, but only within reason.

1ml of 700mg/ml, 29g .5inch insulin syringe is fine. No need for 3ml.
Get the pH right and you're good.
Most vendors don't.
 
600mg/ml L-carn is too hypertonic to be used SubQ, you really need it to be in a muscle, and even then it's better if you add back water to dilute it as much as possible - fill up your 3ml if youre using one

Why tonicity matters

  • Subcutaneous tissue is less vascular than muscle, so fluids stay longer in the interstitial space. Hypertonic or hypotonic solutions can draw water in or out of cells, leading to pain, edema, or even tissue necrosis.
  • Muscle tissue is more vascular, so it clears solutes faster than SC tissue. That means IM can tolerate slightly more variation in osmolality, but only within reason.
I have seen compounding pharmacies issue 200-600mg/ml injectable L-carnitine they're all over in telehealth and fitness/wellness clinics and commonly actively recommend subq for comfort and patient adherance.

I, too, can use chatgpt

  • 600 mg/mL is a common compounding concentration; some pharmacies even offer 200–400 mg/mL to make larger doses easier SubQ.
  • At 1 mL, the osmotic load is well within what adipose tissue can handle if injected slowly and massaged afterward.
  • The issues that lead to tissue injury usually involve:
    • 3–5 mL SubQ boluses,
    • unbuffered or improperly compounded solutions,
    • or repeated high-volume injections into the exact same site.
 
I have seen compounding pharmacies issue 200-600mg/ml injectable L-carnitine they're all over in telehealth and fitness/wellness clinics and commonly actively recommend subq for comfort and patient adherance.

I, too, can use chatgpt

  • 600 mg/mL is a common compounding concentration; some pharmacies even offer 200–400 mg/mL to make larger doses easier SubQ.
  • At 1 mL, the osmotic load is well within what adipose tissue can handle if injected slowly and massaged afterward.
  • The issues that lead to tissue injury usually involve:
    • 3–5 mL SubQ boluses,
    • unbuffered or improperly compounded solutions,
    • or repeated high-volume injections into the exact same site.
I don’t care what your chatbot says, the osmality is too high to use subcutaneously, empower and Olympia offer it as IV and IM, not SC.

Even if you can find another pharmacy that’s offering it for use subQ, it’s not meant to be used that way in that conc and there is not medical literature anywhere that you could show me saying that it’s safe to use in that conc

The only fda approved formulation is 200mg/ml in a 5ml ampule and guaranteed that if they could offer it in smaller amps they would, because a 1ml amp would be significantly cheaper than producing and shipping 5ml amps

600mg per ml levocarnitine is about 3720 mOsm per liter, which is ten times the normal safe range for subcutaneous injection, the accepted range is 280 to 320 mOsm per liter,

To figure out the osmolality of 600mg per ml l-carn, find the molecular weight which is about 161 grams per mole, then convert 600mg per ml into grams per liter which is 600 grams per liter, divide 600 by 161 to get the molarity which is about 3.7 moles per liter, since Lcarn acts like one particle in solution the osmolarity is the same as the molarity, so the osmolality is about 3720 mOsm per liter. Way too high for safe subQ usage. (Even if places are selling it for that)
 
The only fda approved formulation is 200mg/ml in a 5ml ampule and guaranteed that if they could offer it in smaller amps they would, because a 1ml amp would be significantly cheaper than producing and shipping 5ml amps
You keep quoting that without going into the fact that the only FDA approved use case is clinical deficiency of natural l-carnitine, usually for patients in renal failure. It's IV delivered in a larger dose because dialysis patients require the quick restoration since dialysis pulls the l-carnitine from plasma levels and clinically this is the fastest way to replenish l-carnitine levels to physiologic amounts.

FDA does not recognize the use of l-carnitine for fitness or bodybuilding nor in the doses we use or recommend for this purpose.

Also as it pertains to IV use, a lot of compounds require heavy dilution when administered via IV for patient comfort, even if it extends the time for IV infusion. So IV concentrations would generally be lower if it's ready for use, or higher if it's designed to be added to a saline solution bag, since the saline would dilute the compound.
 
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