MESO-Rx
Anabolic Steroids
low DHEA-S
- Thread starter Amgiji
- Start date
Eddie.
Member
Are you on gear now? Are you on gear since the first measurement? What are you taking and what dosages? Do you take HCG now or the time you got your first test? Write down a few things so we can understand
kinda I'm on trt now 120mg topical testosterone per day.
I was not taking anything during the first measurement.
never took HCG.
but I don't seem to need it,
at the time of the most recent DHEA-S test
LH was 5.6 iu/L and FSH was 7.5
It seems to go down on TRT/AAS and also with age. I stopped taking DHEA and my DHEA-S level was down to 104 so I immediately went back on 50mg of DHEA. I also am back on 50mg of pregnenolone too. Make sure to take the micronized versions if you supplement with them.
ah, saw a post that said as much
but I thought I "dodged" that as LH, FSH was fine and pregnenolone was 93 ng/dl also fine.
I guess the question then becomes how screwed am I if it continuous to drop?
I aromatize heavily and IDK if I could handle taking it.
Eddie.
Member
If you're on TRT i suggest to supplement with DHEA, start at 25mg per day and see how it goes. Don't combine it with pregnenolone because you may not handle well one of these 2, better start with one and if everything is smooth then add pregnenolone and see how you react.
I started 25mg DHEA and 10mg preg and it seems i can't tolerate preg. After 3-4 days it gives me brainfog and i feel kinda groggy and depressed. Unfortunately i can't test preg levels in my country and i don't know where i am but the DHEA-S was low to middle levels that's why i started taking it.
If levels are low and you supplement it may enhance cognition and mood as well as improve penis sensitivity, better orgasms and overall erection quality.
I can't say i experienced at a significant level any of the above after supplementing but i didn't have a problem at any of these before. I'm just taking it to prevent depletion and experience the bad side of all these.
I started 25mg DHEA and 10mg preg and it seems i can't tolerate preg. After 3-4 days it gives me brainfog and i feel kinda groggy and depressed. Unfortunately i can't test preg levels in my country and i don't know where i am but the DHEA-S was low to middle levels that's why i started taking it.
If levels are low and you supplement it may enhance cognition and mood as well as improve penis sensitivity, better orgasms and overall erection quality.
I can't say i experienced at a significant level any of the above after supplementing but i didn't have a problem at any of these before. I'm just taking it to prevent depletion and experience the bad side of all these.
Eddie.
Member
And what was your numbers before? This doesn't tell anything.
Starting with 50 per day might be too much, you don't know how much (if any) it raises your e2 so better titrate slow.
The second dhea started to go down on me which was a few years ago I started supplementing with dhea 25/50mg a daily also ran experiments with hcg and hcg without dhea supp I also take pregnenalone 10mg a day sometimes 20mg depends on what I’m trying to achieve
As you can see I run lots of blood work to see the changes also ran plenty of tests while on armidex or aromasin in different applications
My personal point of view on e2 is that if you are not sensitive to it let it be as high as it can get me personally I’d rather keep it high than low.
Never had issues with gyno acne or anything else related to high e2 BUT can def say while it’s the highest I can loose my shit really quickly..
Don’t be afraid of estrogen buddy and dhea/pregnenalone aint estrogen pills..
Eddie.
Member
With 25mg DHEA i'm ok, when i add 10mg of preg after 3-4 days i feel like shit. Tried both in morning, tried DHEA morning and preg pre bed, still shit so i ditched it and taking only dhea.
You can try testing for progesterone, is not the same but if you test for it and for DHEA-S you can already have a good idea of your neuro-steroid concentrations.
Eddie.
Member
Yes you're kinda right, normally an intolerance on preg could mean high progesterone but in my case it wasn't that. I tested progesterone when i tested dhea-s and they were both low. (these levels are from last October just before i leave the natty train). Progesterone was 1,07 nmol/l (0,9 - 3,9) and DHEA-S was 1,52 mg/ml (0,35 - 5,7) so high progesterone was definitely not the reason i couldn't handle pregnenolone.
Make sure you get a good company for both dhea and preg I find it hard to believe that preg alone or with dhea at 10mg caused you this I ran preg at 50mg a day and had no issue some supplements company use ton of toxic shit in their supplements and certain people can react to that always read the label of what is included in your supplements sometimes paying extra 10 bucks is worth it..
I had bad reaction/feeling on other different supplements and the second I switched to a better (cleaner) version of that same supplement I felt great with no issues.
(I keep my progesterone slightly above the ref range)
Eddie.
Member
DHEA is from Natrol and preg from Source Naturals, both from i herb but none of the is micronized. It was hard to source these 2 micronized. Maybe i'll try to find micronized pregnenolone from a different company and try again.
These are the brands that I tried (and currently use) with no issue.
They do contain unwanted shit but it’s minimal.
If you’ll find cleaner version let me know.
Good luck!
Eddie.
Member
That's the one that i have, in the middle.. Source Naturals 10mg.
(I take the same berberine too)
Unfortunately the one that we both take also contain chemicals but from what I searched it’s less than other brands regarding berb yeah it’s the good one exp also .. I have 3 whole shelfs of supplements (and a small fridge for smelly supplements like nac and selenium)I’d say I spend more money on supplements than gear lol..
Well that is a good question and hard to answer because the data on these precursor hormones for men on androgens is limited, so a lot of what we go off of is also anecdotal.
I can speak for myself again as far as pregnenolone is concerned. If I test it, my result is <10 and even if I take it, it doesn't seem to move much, most likely because it's being converted to other hormones since it's the "mother" hormone.
I have seen somewhere that Pregnenolone Sulfate levels are more accurate, however, I haven't found anywhere that tests for Preg Sulfate (if someone knows a lab that tests it, please share).
I can't say whether yours will continue to decline the longer you are suppressed though. I just don't know the answer.
I find it interesting how much everyone's response to pregnenolone varies. Some people say they feel great on it and others feel worse on a low dose. I wonder what the mechanism is behind feeling worse on it. I suspect it could be progesterone going too high but I really am not sure.
Some of these brands aren't micronized, like the Life Extension brand for instance, which is normally a good company. I know the MRM Pregnenolone is micronized though, so that one should be good.
Speaking from experience, I did raise my DHEA-S on non micronized DHEA if I tested it right after taking the supplement, but it is much shorter acting.
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