Low IGF - Can tirz cause this?

According to current research, GLP-1 (glucagon-like peptide-1) can indirectly lower IGF-1 (insulin-like growth factor-1) levels by stimulating the release of growth hormone (GH), which can then lead to a decrease in IGF-1 binding protein levels, ultimately resulting in lower total IGF-1 concentrations in the body
 
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