Low iron, high platelets and -cytes while on cycle

[klokke23]

Hello.

My bloods show a lot of these -cytes being high, while iron is low. Does anyone have any clue what might be going on and what I need to do?

600 test/600 primo. Week 14

 

[xlincharge]

Hello.

My bloods show a lot of these -cytes being high, while iron is low. Does anyone have any clue what might be going on and what I need to do?

600 test/600 primo. Week 14

View attachment 260354

If you donate blood regularly that could be a reason for low iron. You may have pulled at a time quite far away from your last donation?

Also when you blast and then come off you will have higher cell counts normally and sometimes low iron because the extra cells produced during your blast may not have an adequate amount of iron yet at the time you pull.

The shitty thing is, you can take an iron supplement regularly but then you risk putting cell counts even higher. Its a fine line my friend but not uncommon IMO.

 

[Jin23]

Hello.

My bloods show a lot of these -cytes being high, while iron is low. Does anyone have any clue what might be going on and what I need to do?

600 test/600 primo. Week 14

View attachment 260354

Looks like an infection or some other inflammatory condition. You didn't test crp? And what's your ferritin?

The low iron is frequently a sign of infection/disease as iron utilization goes way up during such a condition. However, if iron loading is compromised during high epo stimulation (like androgens do) you might end up iron deficient but imo this is not common occurrence during steroid use, usually the opposite is true.

How are you feeling?

 

[klokke23]

Looks like an infection or some other inflammatory condition. You didn't test crp? And what's your ferritin?

The low iron is frequently a sign of infection/disease as iron utilization goes way up during such a condition. However, if iron loading is compromised during high epo stimulation (like androgens do) you might end up iron deficient but imo this is not common occurrence during steroid use, usually the opposite is true.

How are you feeling?

Thank you!

I find this strange because I feel completely normal. Sleep is a tad worse because I'm on cycle. And my apetite is severely lowered, which is not common for me. But other than that I feel fine and have felt fine the last few months. Bo sickness.

Should I get crp to rule out relation to disease/inflammation?

 

[Jin23]

Thank you!

I find this strange because I feel completely normal. Sleep is a tad worse because I'm on cycle. And my apetite is severely lowered, which is not common for me. But other than that I feel fine and have felt fine the last few months. Bo sickness.

Should I get crp to rule out relation to disease/inflammation?

You should include hsCRP in all your blood work, always, it's a very good marker. Also include ferritin. If you knew what your ferritin is atm, diagnosis would be a bit easier. If ferritin is high but serum iron and TSAT low, then you know you have inflammation issues when cbc looks normal. Include normal crp now too if hscrp has a limited upper range as your crp might be quite high.

But if wbc's are all high, then there might be some bacterial/viral thing going on. Hard to distinguish between the two, but my guess if anything would be bacterial.

Also check you sedimentation. And a more detailed wbc can give you more insight.

I'd definitely lower your dosages to trt, as you've got some issues especially as gear is probably causing it. What's you RHR and bp?

 

[xlincharge]

You should include hsCRP in all your blood work, always, it's a very good marker. Also include ferritin. If you knew what your ferritin is atm, diagnosis would be a bit easier. If ferritin is high but serum iron and TSAT low, then you know you have inflammation issues when cbc looks normal. Include normal crp now too if hscrp has a limited upper range as your crp might be quite high.

But if wbc's are all high, then there might be some bacterial/viral thing going on. Hard to distinguish between the two, but my guess if anything would be bacterial.

Also check you sedimentation. And a more detailed wbc can give you more insight.

I'd definitely lower your dosages to trt, as you've got some issues especially as gear is probably causing it. What's you RHR and bp?

Well poop, I bungled that. I didn't bother to look at the report. I assumed he had high rbc, hemoglobin and hematocrit from his statement. This does not appear to be the case.

@klokke23 disregard what I said about the above (rbc, crit, globin). @Jin23 I did not know about disease and inflammation lowering iron. Learn something new every day. Now I am curious and will look into the mechanisms.

An iron panel for sure will have different markers including ferritin and will give OP a more targeted look at possible reasons for low iron.

I don't think OP wbc counts are a huge issue but to be sure and get peace of mind if he is concerned I agree with the advice.

Thanks for the insight.

 

[Jin23]

Well poop, I bungled that. I didn't bother to look at the report. I assumed he had high rbc, hemoglobin and hematocrit from his statement. This does not appear to be the case.

@klokke23 disregard what I said about the above (rbc, crit, globin). @Jin23 I did not know about disease and inflammation lowering iron. Learn something new every day. Now I am curious and will look into the mechanisms.

An iron panel for sure will have different markers including ferritin and will give OP a more targeted look at possible reasons for low iron.

I don't think OP wbc counts are a huge issue but to be sure and get peace of mind if he is concerned I agree with the advice.

Thanks for the insight.

Inflammation increases hepcidin which prevents iron absorption from food and importantly prevents iron export from macrophages and liver/spleen to blood. It's called anemia of chronic disease/inflammation.

 

[klokke23]

You should include hsCRP in all your blood work, always, it's a very good marker. Also include ferritin. If you knew what your ferritin is atm, diagnosis would be a bit easier. If ferritin is high but serum iron and TSAT low, then you know you have inflammation issues when cbc looks normal. Include normal crp now too if hscrp has a limited upper range as your crp might be quite high.

But if wbc's are all high, then there might be some bacterial/viral thing going on. Hard to distinguish between the two, but my guess if anything would be bacterial.

Also check you sedimentation. And a more detailed wbc can give you more insight.

I'd definitely lower your dosages to trt, as you've got some issues especially as gear is probably causing it. What's you RHR and bp?

I'll look into getting a new blood test soon.
I don't have bp measure atm. RHR is 68
So I should not just take iron supplements and call it a day? Friend of mie suggested that but all the wbc markers will then go up even more?

 

[Jin23]

I'll look into getting a new blood test soon.
I don't have bp measure atm. RHR is 68
So I should not just take iron supplements and call it a day? Friend of mie suggested that but all the wbc markers will then go up even more?

If you're ferritin is high, meaning low serum iron is from inflammation and your iron stores are high but non accessible, then no, not in my opinion, but I'm not a doc mind you.

If ferritin is low, it would make more sense, but either way, you've got an issue of which changes in iron metabolism are just a symptom not a cause.

 

[klokke23]

If you're ferritin is high, meaning low serum iron is from inflammation and your iron stores are high but non accessible, then no, not in my opinion, but I'm not a doc mind you.

If ferritin is low, it would make more sense, but either way, you've got an issue of which changes in iron metabolism are just a symptom not a cause.

Doc wants to wait a little before drawing bloods again. I'll just take some iron and hopefully I won't die.

I'll get a BP measurer while I'm at the pharmacy.

 

[onefinalrep]

Anyone know a solution to having high rbc counts on cycle or even cruise, dropping dose significantly only to have low iron levels including ferritin on the next set of bloods (with normal rbc counts)?
I can't win it always seems to be one or the other. Anyone else experience this?