Man 43 years old

[frank282]

Good morning

I am a 43 year old boy, I weigh 66 kg and I am 168 cm tall.

I am on TRT because I am hypogonadal, my current therapy requires 0.2 ml of enanthate every 4 days, it would be 250 mg every 3 weeks.

I am posting my blood tests done 7 days after the administration of 0.2 ml of test.

I would like your opinion if there is room for improvement because I do not feel very well and I do not notice any significant physical changes especially because I suffer from night binges disorder.

1. COMPLETE BLOOD COUNT (CBC)​

Method: Laser Cytophotometry

• WHITE BLOOD CELLS (WBC): 8,040 /mm³ *(4,000 - 10,000)*
• RED BLOOD CELLS (RBC): 4,530,000 /mm³ *(4,500,000 - 6,000,000)*
• HEMOGLOBIN (Hb): 13.8 g/dL *(11.8 - 16)*
• MCV (Mean Corpuscular Volume): 94.7 fL *(82 - 98)*
• MCH (Mean Corpuscular Hemoglobin): 30.5 pg *(27 - 32)*
• MCHC (Mean Corpuscular Hemoglobin Concentration): 32.2 g/dL *(32 - 38)*
• RDW (Red Cell Distribution Width): 16.7% *(11.5 - 14.5)*
• HEMATOCRIT (Hct): 42.9% *(40 - 54)*
• PLATELETS: 253,000 /mm³ *(130,000 - 400,000)*

WHITE BLOOD CELL DIFFERENTIAL​

• NEUTROPHILS: 58.8% *(60 - 70)*
• LYMPHOCYTES: 27.6% *(20 - 35)*
• MONOCYTES: 8.5% *(2 - 10)*
• EOSINOPHILS: 4.3% *(1 - 6)*
• BASOPHILS: 0.8% *(0 - 1)*

1. 17-BETA ESTRADIOL​

• Value: 7.6 pg/mL *(20 - 60)*
• Method: ECLIA, Roche

1. TESTOSTERONE​

• Value: 5.62 ng/mL *(2.8 - 8)*
• Method: ECLIA, Roche

1. FREE TESTOSTERONE​

• Value: 18.10 pg/mL
  
  • Reference Ranges:
    
    • 10-20 years: 18.5 - 48.3 pg/mL
    • 20-30 years: 19.8 - 51.7 pg/mL
    • 30-50 years: 16.1 - 47.9 pg/mL
    • >50 years: 12.1 - 39.6 pg/mL
• Method: CLIA

1. PSA (Prostate-Specific Antigen)​

• Value: 0.38 ng/mL *(0.1 - 4)*
• Method: ECLIA

 

[frank282]

Good morning I am a 43 year old boy, I weigh 66 kg and I am 168 cm tall. I am on TRT because I am hypogonadal, my current therapy requires 0.2 ml of enanthate every 4 days, it would be 250 mg every 3 weeks. I am posting my blood tests done 7 days after the administration of 0.2 ml of test. I would like your opinion if there is room for improvement because I do not feel very well and I do not notice any significant physical changes especially because I suffer from night binges disorder.

1. COMPLETE BLOOD COUNT (CBC)​

Method: Laser Cytophotometry

• WHITE BLOOD CELLS (WBC): 8,040 /mm³ *(4,000 - 10,000)*
• RED BLOOD CELLS (RBC): 4,530,000 /mm³ *(4,500,000 - 6,000,000)*
• HEMOGLOBIN (Hb): 13.8 g/dL *(11.8 - 16)*
• MCV (Mean Corpuscular Volume): 94.7 fL *(82 - 98)*
• MCH (Mean Corpuscular Hemoglobin): 30.5 pg *(27 - 32)*
• MCHC (Mean Corpuscular Hemoglobin Concentration): 32.2 g/dL *(32 - 38)*
• RDW (Red Cell Distribution Width): 16.7% *(11.5 - 14.5)*
• HEMATOCRIT (Hct): 42.9% *(40 - 54)*
• PLATELETS: 253,000 /mm³ *(130,000 - 400,000)*

WHITE BLOOD CELL DIFFERENTIAL​

• NEUTROPHILS: 58.8% *(60 - 70)*
• LYMPHOCYTES: 27.6% *(20 - 35)*
• MONOCYTES: 8.5% *(2 - 10)*
• EOSINOPHILS: 4.3% *(1 - 6)*
• BASOPHILS: 0.8% *(0 - 1)*

1. 17-BETA ESTRADIOL​

• Value: 7.6 pg/mL *(20 - 60)*
• Method: ECLIA, Roche

1. TESTOSTERONE​

• Value: 5.62 ng/mL *(2.8 - 8)*
• Method: ECLIA, Roche

1. FREE TESTOSTERONE​

• Value:18.10 pg/mL
  • Reference Ranges:
    • 10-20 years: 18.5 - 48.3 pg/mL
    • 20-30 years: 19.8 - 51.7 pg/mL
    • 30-50 years: 16.1 - 47.9 pg/mL
    • >50 years: 12.1 - 39.6 pg/mL
• Method: CLIA

1. PSA (Prostate-Specific Antigen)​

• Value: 0.38 ng/mL *(0.1 - 4)*
• Method: ECLIA

could someone give me some advice?

I'm changing the frequency to 0.2 ml every 3.5 days, in total 100 mg per week of pharmacy enanthate

 

[Ghoul]

Why split such a low dose?

 

[Bobertson]

Are you taking an AI preventatively such as anastrozole? If so, stop. Your estradiol is out of range low.

 

[frank282]

Why split such a low dose?

Why split such a low dose?

the initial prescription was 250 mg every 3 weeks, but I decided to divide it because I was fine the first week and then bad the next two weeks. so I inject twice a week the total dose is a little higher from 86 to 100 mg.

 

[frank282]

Are you taking an AI preventatively such as anastrozole? If so, stop. Your estradiol is out of range low.

no only testo

 

[Eddie.]

That's pretty low dose, you're 43 not 73.. I'd like to be on the top of reference range. Is it a trt through a clinic? Prescribed by doctor? Or you do it by yourself?

Raising testosterone dose will raise T levels and estradiol levels as well. That estradiol is way too low.. you don't aromatise probably because you're either lean (guessing) and definitely because there's not much testosterone to convert from. If you insist on keeping that low test dose at least add HCG, 250IU every other day. This will bump a little your T levels and estradiol.

 

[frank282]

therapy Prescribed by doctor but 250 mg for 3 week, but now from 3 month i split in 2 dose weekly. I'm 66 kg for 168 cm some fat in the abs

 

[Eddie.]

Yeah, good luck with that. You either speak to him and discuss your concerns, symptoms and low numbers (estradiol mainly) or find a new one.

Generally a doctor who's prescribing 250mg test E once every 3 weeks must be completely ignorant.

 

[Ateam2023]

Yeah, good luck with that. You either speak to him and discuss your concerns, symptoms and low numbers (estradiol mainly) or find a new one.

Generally a doctor who's prescribing 250mg test E once every 3 weeks must be completely ignorant.

i just had my appointment with "the kidney specialist" , who was an older dr, that knew NOTHING about trt protocols , (not that he should , but he didn't even know typical testosterone ranges) and tried running some things on me that didn't make any sense, i merely asked him "are current with the latest trt protocols ", which He was not, just because they are dr's , doesn't mean squat, i find this to be true with older dr's , they are stuck in the past,, i much rather have younger dr because likely they are more versed in newer protocols,,

 

[Mrhairyman]

could someone give me some advice?

I'm changing the frequency to 0.2 ml every 3.5 days, in total 100 mg per week of pharmacy enanthat

I personally found micro dosing daily helped a lot, especially with my estrogen levels.
Have you thought about pinning 15- 20mg daily ?

 

[Eddie.]

i just had my appointment with "the kidney specialist" , who was an older dr, that knew NOTHING about trt protocols , (not that he should , but he didn't even know typical testosterone ranges) and tried running some things on me that didn't make any sense, i merely asked him "are current with the latest trt protocols ", which He was not, just because they are dr's , doesn't mean squat, i find this to be true with older dr's , they are stuck in the past,, i much rather have younger dr because likely they are more versed in newer protocols,,

Exactly! It seems like we have to send them a questionnaire before they start treating us lol. They may be good on their "field" but if other parameters are adjusted for x,y reason, like in case of kidney specialist who has to treat a person that's on TRT (using copious amount of gear is another story) then you may have to test and try a different method of treat on that person. They're just too one sighted. TBH we're not the "easiest" patients because we know some things average people don't, but we're still looking for the best outcome.

IMO, if you feel something is not right with a doctor's approach, discuss it with him and if you still don't feel confident with what's he's saying, then seek another one.

I personally found micro dosing daily helped a lot, especially with my estrogen levels.
Have you thought about pinning 15- 20mg daily ?

Microdosing vs bolus doses reduces the conversion to estradiol, he needs to raise it so definitely more frequent pins won't help at all.

 

[frank282]

Guys, I wanted to ask if the low conversion into estrogen could be due to a nutritional issue?

 

[frank282]

I'm posting my blood tests after 8 weeks of taking 125 mg of enanthate per week, divided into two doses: Tuesday and Friday. Please evaluate the correct ratio with estrogen because I think something is wrong. I aromatize a little.

PSA​

• Specific Prostatic Antigen (PSA): 0.66 ng/ml
  (Normal value: below 4 ng/ml)

---

Thyroid Profile​

• FT3 (Triiodothyronine): 2.97 pg/ml
  Euthyroidism 1.5 – 4.0; Hyperthyroidism >4.0; Hypothyroidism <1.5
• FT4 (Thyroxine): 14.60 pmol/L
  Euthyroidism 10 – 20; Hyperthyroidism >20; Hypothyroidism <10
• TSH (Thyroid Stimulating Hormone): 1.63 nUI/ml
  Euthyroidism 0.40 – 5.0; Hyperthyroidism <0.40; Hypothyroidism >5.0

---

Other Hormones​

• Prolactin (PRL): 8.53 ng/ml
  Men: 1.5 – 25; Women, fertile age: 5.0 – 35; Menopause: 1.5 – 25
• Estradiol (E2): 12.35 pg/ml
  Men: < 42; Women: follicular phase 10 – 160, ovulatory peak 150 – 400, luteal phase < 50, menopause < 40, pregnancy > 800

---

Folate & Ferritin​

• Folic Acid: 11.90 ng/ml
  (Normal value: 10 – 33)
• Ferritin: 112.60 ng/ml
  Men: 20 – 300; Cycling women: 10 – 160; Menopausal women: 25 – 280; Newborn: 200 – 600; 2–5 months: 50 – 200; 6 months–15 years: 8 – 142

---

Blood Chemistry​

• Glycemia (fasting): 77 mg/dl, 25/10/2025
  (Normal range: 60 – 110 mg/dl)
• Azotemia: 49 mg/dl (Normal: 10 – 50)
• Creatinine: 0.95 mg/dl (Normal: 0.60 – 1.50)
• AST (G.O.): 25 U/l (Normal: > 40)
• ALT (G.P.): 29 U/l (Normal: > 40)
• Total Cholesterol: 131 mg/dl (Normal: < 200)
• Triglycerides: 60 mg/dl (Normal: 50 – 190)
• LDL Cholesterol: 75 mg/dl (Normal: < 100)
• HDL Cholesterol: 42 mg/dl (Normal: > 35)
• Albumin: 4.25 g/dl (Normal: 3.50 – 5.10)

---

Vitamin Profile​

• Vitamin B12: 1,142 pg/ml (Normal: 180 – 900)
• Vitamin D (1,25-OH): 27.60 ng/ml (Normal: 30 – 100)

---

Andrology / Endocrinology​

• Testosterone: 10.56 ng/ml (Men: 2.5 – 14.0; Women: 0.3 – 1.0)
• Cortisol: 17.80 ug/dl (Normal: 5 – 20)
• ACTH: 1.88 pg/ml (Normal: 0 – 46)
• Baseline Insulin: 0.40 mU/ml (Normal: 3 – 25)
• SHBG: 48 nmol/l (Normal: 13 – 71)

---

IGF-1​

• Insulin-like Growth Factor 1: 122 ng/ml, 25/10/2025
  (Normal: 89 – 225)

WBC	6.44 x10^9/L	4.00 – 10.00
HGB	14.8 g/dL	13.0 – 17.0
Platelets (PLT)	230 x10^9/L	100 – 400
Neutrophils	61.5%	50.0 – 70.0
Lymphocytes	28.7%	20.0 – 40.0

[th]

Parameter​

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Result​

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Normal Range​

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[frank282]

WBC (White Blood Cells)	6.44 x10⁹/L	4.00 – 10.00
Neu% (Neutrophils %)	61.5%	50.0 – 70.0
Lym% (Lymphocytes %)	28.7%	20.0 – 40.0
Mon% (Monocytes %)	6.7%	2.0 – 8.0
Eos% (Eosinophils %)	2.2%	0.5 – 5.0
Bas% (Basophils %)	0.9%	0.0 – 1.0
Neu# (Neutrophils absolute)	3.96 x10⁹/L	2.80 – 7.00
Lym# (Lymphocytes absolute)	1.85 x10⁹/L	1.00 – 4.80
Mon# (Monocytes absolute)	0.44 x10⁹/L	0.12 – 1.00
Eos# (Eosinophils absolute)	0.14 x10⁹/L	0.02 – 0.50
Bas# (Basophils absolute)	0.05 x10⁹/L	0.00 – 0.10
RBC (Red Blood Cells)	4.48 x10¹²/L	3.50 – 5.50
HGB (Hemoglobin)	14.8 g/dL	13.0 – 17.0
HCT (Hematocrit)	43.8%	37.0 – 54.0
MCV (Mean Corpuscular Volume)	97.8 fL	81.0 – 99.0
MCH (Mean Corpuscular Hemoglobin)	33.0 pg	27.0 – 34.0
MCHC (Mean Corpuscular Hemoglobin Concentration)	33.8 g/dL	32.0 – 36.0
RDW–CV (Red Cell Distribution Width–CV)	12.6%	11.5 – 14.0
RDW–SD (Red Cell Distribution Width–SD)	53.4 fL	35.0 – 56.0
PLT (Platelets)	230 x10⁹/L	100 – 400
MPV (Mean Platelet Volume)	9.7 fL	6.5 – 12.0
PDW (Platelet Distribution Width)	16.2 fL	10.0 – 18.0
PCT (Plateletcrit)	0.223%	0.108 – 0.282

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Parameter​

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Result​

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Reference Interval​

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[Country Club Hero]

therapy Prescribed by doctor but 250 mg for 3 week, but now from 3 month i split in 2 dose weekly. I'm 66 kg for 168 cm some fat in the abs

I bet you would feel fantastic on 100-125mg every 5 days.

 

[frank282]

Scommetto che ti sentiresti benissimo con 100-125 mg ogni 5 giorni.

actualy 125 week

 

[Sera]

Your estradiol is surprisingly low, I wonder if anyone has any idea why.

 

[frank282]

Your estradiol is surprisingly low, I wonder if anyone has any idea why.

this is the problem i think

 

[Sera]

this is the problem i think

Are you a very lean man? Low body fat is associated with low levels of aromatase enzyme.

I think it is very rare for people to not get sufficient estradiol with injectable testosterone from their aromatase enzyme. Some outliers like you I suppose genetically have not much of this enzyme.

It is possible to use something called hcg to increase estradiol. It stimulates the testes to produce testosterone and estrogen and it is known to produce more estrogen than testosterone alone.

It would also technically help to increase testosterone dose but that could cause undesirable side effects over time like excessive red blood cell count.