Modafinil for pain relief.

[MrGrant]

On another site I am on someone has used provigil and it has helped with their pain from Multiple Scelorsis (mainly pain in the lower half of body and hands.) There are many papers on this which (I think show) it helps with the general fatigue leading to easier day to day activities but not currently prescribed for it (and I dont think saying its directly helping with pain?) .

Has anyone any experience with using it and its helped with any pain management (any serious pain issue)? If so was it prescribed or recommended for it? Any info greatly appreciated.

Various abstracts;

Modafinil for multiple sclerosis fatigue: does it work? - PubMed

This suggests that modafinil may be useful, particularly when MS fatigue is associated with sleepiness. The relationship between fatigue and excessive daytime sleepiness is poorly understood and needs to be better defined before appropriate measures of the most clinically relevant outcomes can...

pubmed.ncbi.nlm.nih.gov

Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study - PubMed

Treatment with modafinil significantly improves fatigue and sleepiness and is well tolerated by patients with MS. Unlike the higher dose regimen required in narcolepsy, a low-dose regimen of modafinil is effective in MS.

pubmed.ncbi.nlm.nih.gov

(more below each paper)

@Ghoul tagging you in here mate in case you've seen or heard anything concrete about it?

 

[latenightdevil]

It helps me with chronic fatigue but not with pain. The top things in my pain stack are harpagophytum, matrine, 3 different nanocurcumins, and palmitoylethanolamide.

 

[Barney67]

Do you know the cause of your pain?

 

[MrGrant]

@Barney67
Thanks for writing, its not me who has the issue but its caused by MS, they are on morphine too and are hoping to wean off the morphine in time in the hopes the moda (and NSAID's) can help with it.
A med pro has answered (who prescribes moda for patients) saying she cant see the mechanism of action but perhaps an unrecognised synergistic effect.

 

[bananafeet]

Certain SSRIs and SNRIs can help with certain pain. Like neuropathic pain.

So can nandralone for joint pain.