Nandrolone effect on LPa

[Theworm]

Effect of Nandrolone Decanoate on Serum Lipoprotein (a) and its isoforms in hemodialysis patients

Malnutrition, anemia and increased atherosclerosis are the main causes of mortality in hemodialysis patients. Therapies designed to improve the disorders might therefore be expected to improve outcome. The effects of Nandrolone Decanoate (ND), in 64 stable ...

www.ncbi.nlm.nih.gov

So nandrolone decreases LPa, which should be cardio protective. I wonder if the lowering of LPa overpowers the decrease in HDL or elevation of LDL?

 

[Type-IIx]

Oral Steroid and Cholesterol

Hi everyone. By what mechanism do oral steroids impact our cholesterol in a negative way?

thinksteroids.com

 

[SenorSuperdrol]

Effect of Nandrolone Decanoate on Serum Lipoprotein (a) and its isoforms in hemodialysis patients

Malnutrition, anemia and increased atherosclerosis are the main causes of mortality in hemodialysis patients. Therapies designed to improve the disorders might therefore be expected to improve outcome. The effects of Nandrolone Decanoate (ND), in 64 stable ...

www.ncbi.nlm.nih.gov

So nandrolone decreases LPa, which should be cardio protective. I wonder if the lowering of LPa overpowers the decrease in HDL or elevation of LDL?

I’m sure it’s difficult for everyone, but nandrolone raises my CRP a bit. Which can be bad for endothelial glycocalyx, and plaque deposits. However I still use it as I seem to do well and not get sides from it.

Have you done an LP(a) test yet whist on trt to see how much you have genetically.

I’m fortunate that my LP(a) is <8.4 and undetectable.

 

[Type-IIx]

It is currently the majority view that Lp(a) as determined by genetic-heritable factors is an independent risk factor not particularly amenable to clinically significant modification. For example, while niacin lowers Lp(a) and small LDL particles/VLDL significantly, it doesn't actually reduce risks of coronary events. Know what your Lp(a) is, certainly. But, for now at least, lifestyle & statins are still the best treatment currently available.

However, PCSK9 inhibitors are very interesting; and might revolutionize treating atherosclerotic disease when combined with a statin. They're just currently quite novel; and expensive.