New anti-e: aromasin

[Stez]

Anyone had any experience with aromasin? It's a new anti-aromatase.

Meant to be very effective without the negative of letro etc. I'm possibly going to be trying it soon.

 

[mranak]

What negatives of Letrozole are you referring to? I don't know of any negative side effects from any of the aromatase inhibitors, except for side effects caused by changes in estradiol. For example, bringing your estradiol down too low will damage your lipid profile. That's just the AI doing its job and all of the available AIs will do that if you take too much.

 

[Desmo996]

I think he is referring to the reduction in IGF-1 levels that some are believed to cause.

 

[Ender]

There's also this "rumor" on BB forums that aromasin doesn't cause problems with HDL levels as do other AA class drugs. The ticket to maintaining healthy lipid profiles, though, isn't the drug used to control E2 but rather the level to which E2 is allowed to drop (or not).

 

[Stez]

Yah, I'm referring to the cholestoral issues with letro.

Something to note is that bodybuilders who had their labido killed by letro, dont get that effect with aromasin. They think it's not just e2 going too low, it's osmething else but don't know what it is.

Here is a thread with some good articules and discussion starting about half way down the page

http://www.anabolex.com/forums/showthread.php?t=155362

 

[Ender]

Yah, I'm referring to the cholestoral issues with letro.

Something to note is that bodybuilders who had their labido killed by letro, dont get that effect with aromasin. They think it's not just e2 going too low, it's osmething else but don't know what it is.

Here is a thread with some good articules and discussion starting about half way down the page

http://www.anabolex.com/forums/showthread.php?t=155362

I've seen much of this before.

The primary negative that comes to mind is impact on lipid profile. I can tell you from first hand experience that if my E level is managed to even very low-normal levels I continue to have an excelent lipid profile on appropriate TRT. Actually, that's even the case when T got elevated somewhat above "normal" and E was a bit over supressed. This was on Arimidex. I can also tell you, from more than a half-dozen lab reports, that when I was cycling the SAME low-normal E levels along with very elevated T levels always resulted in a horrible lipid profile. I did use Aromasin when I cycled and the imapct was nearly the same as having used Arimidex. Extreme elevations in T, or the use of oral AAS, is overwhelmingly bad for lipid profiles.

As for libido...not sure. I do suspect that extreme elevations in T, even with well managed E (not low), result in negative impact to sexual function. No proof though. I say this because when my T levels exceed the "normal range" by some 15% to 20% (while tuning TRT) or so I will notice libido start falling a bit, not much. More pronounced, though, will be dramatic changes in my ability to ejaculate. Delayed ejaculation seems like such a novel idea...until you experience it. This side has been consistent with both low-normal E, normal lipids, etc. The variable seems to be increasing DHT and T and dramatically increased free-T.

I can attest that I have a very normal, very active, libido with my total-T at just about the median and E at low-normal levels. I am using androgel and arimidex presently. My total T is somewhere in the 600 range (400-800ish Quest reference), free-T is solidily in the middle, E is at 12 (10-50). I do tend to have problems with fat gain and nipple tenderness if my E approaches the median, which I still find confusing.

 

[Stez]

Thank u for your awesome response ender.

Can i ask u how much test u take, and what anti-e u use and how much? Thanks heaps.

 

[Matt Muscle]

Ender, How are you dosing the arimidex at the moment? How do you prevent your E from going to low with this powerfull stuff? I also have this delayed ejaculation problem sometimes(mostly) ..its more like the sensation starts to build then it just dies down...every now and again I get "normal function" but it only lasts for a day or so. What also concerns me is that my ejac levels are generally quite low..even on Hcg... it takes about 4 days for them to build up and even then its certainly not what i would call healthy!
I often wonder that since FSH is not being produced anymore due to TRT, that for some guys... this affects semen quality and quantity greatly..

 

[Ender]

Ender, How are you dosing the arimidex at the moment? How do you prevent your E from going to low with this powerfull stuff? I also have this delayed ejaculation problem sometimes(mostly) ..its more like the sensation starts to build then it just dies down...every now and again I get "normal function" but it only lasts for a day or so. What also concerns me is that my ejac levels are generally quite low..even on Hcg... it takes about 4 days for them to build up and even then its certainly not what i would call healthy!
I often wonder that since FSH is not being produced anymore due to TRT, that for some guys... this affects semen quality and quantity greatly..

Arimidex .25mg EOD.

Delayed ejactulation. What you just described is the dirty little secret of the steroid world. Once in a while a guy will post "I'm on [lots] of Test and have decent libido but can't ejaculate...or it takes forever...and it's all clumpy when it comes out...there's no volume...doesn't feel right...feels like I get 'right to the edge' and suddenly it all falls apart." Once in a while there will be posts from such guys and a few others come out of the woodwork saying "similar happens to me...you need MORE ldex...your E is TOO LOW..." No one has the answer though. More often than not you get some 19 to 22yo kid saying, "What are you talking about I'm always horny and everything works great". It's the older guys, say late 20's and up, that report this "things don't work right" symptom.

Well, I used to wonder about it...Now I'm pretty convinced its a result of elevated T levels. Whether it's free-T getting too high or total is too high or DHT elevating too much as a result of T doesn't matter the result is the same. I'm pretty sure it's NOT E or Arimidex.

I started TRT with high E2 and high (both at 100% of normal range) total E. Libido and sexual function improved dramatically after starting the androgel, even though E2 climbed and Total-E doubled. Then using Arimidex we ended-up destroying my E2 level (6 on a 10-50 scale) as my pharm had the lable at 3X Swale's writen order. Still libido was great. Then stepping back the adex and increasing the T a little got me to an E of 12 and a mid-normal T...libido great. Then increased the Androgel 50%...T and free-T sky-rocketed...E stayed at 12...libido good...sexual performance bad. I noticed the sexual sides about 4dy post androgel increase. They "corrected" about 5dy after lowering dosages a notch.

I know what it's like to want a "fix" unfortunately I think this is "just how it works" we're not supposed to have really elevated T levels.

 

[Ender]

Thank u for your awesome response ender.

Can i ask u how much test u take, and what anti-e u use and how much? Thanks heaps.

I am on 6.25mg Androgel ED and .25mg Arimidex ED. I had hoped to maintain some sort of anominity on here...a place to talk without my Doc scrutinizing words/actions. Unfortunately, I think I've blown that now.

 

[pmgamer18]

I have been on TRT since I was 40 now 61 when I turned into my 50's I started having trouble with ED and reaching an orgasm. Up untill last year. I was unable to have sex with my wife for over 10 yrs. I was very disappointed when Viagra came out it did nothing for me. Last year I found out about high E2 Estradiol in men and got my Dr. to test me I was very high.
Having high E2 caused me a lot of problems it gave me ED, trouble reachiing an orgasm, low pain in my prostate, troulble voiding, brain fog, panic attacks and skin rashs. When I got my E2 down all of the above went away except the ED but it got 80% better enough to have sex. My Dr. gave me Cialis 20 mgs. I take it every 72 hrs. and can have sex anytime now and no problems reaching an orgasm. I has been a long battle but now I am back and doing great. It gets up just thinking about sex. This is what high E2 did to me robbed me of my sex life.
Phil

 

[novicebb]

Anyone had any experience with aromasin? It's a new anti-aromatase.

Meant to be very effective without the negative of letro etc. I'm possibly going to be trying it soon.

No experience with aromasin personally. I know that it is extremely expensive and that explains why you don't see much in the way of "for research only" liquid formulas. I know that it isn't as effective as Letrozole and I would rather take a sterile Formastane injectable of 250-350mg per week then aromasin anyway.

 

[Matt Muscle]

Arimidex .25mg EOD.

Delayed ejactulation. What you just described is the dirty little secret of the steroid world. Once in a while a guy will post "I'm on [lots] of Test and have decent libido but can't ejaculate...or it takes forever...and it's all clumpy when it comes out...there's no volume...doesn't feel right...feels like I get 'right to the edge' and suddenly it all falls apart." Once in a while there will be posts from such guys and a few others come out of the woodwork saying "similar happens to me...you need MORE ldex...your E is TOO LOW..." No one has the answer though. More often than not you get some 19 to 22yo kid saying, "What are you talking about I'm always horny and everything works great". It's the older guys, say late 20's and up, that report this "things don't work right" symptom.

Well, I used to wonder about it...Now I'm pretty convinced its a result of elevated T levels. Whether it's free-T getting too high or total is too high or DHT elevating too much as a result of T doesn't matter the result is the same. I'm pretty sure it's NOT E or Arimidex.

.

Very interesting Ender, thankyou for your reply! Yes I have had very similar thoughts myself. Each individual is indeed different and they may have a different "upper level" which once exceeded causes many sexual problems... especially as you say to the older guys! Possibly, relying on the upper level set by Labs is also a mistake too... as this could be too high for some people.... great for muscle building, but not sexual function.

 

[Ender]

Very interesting Ender, thankyou for your reply! Yes I have had very similar thoughts myself. Each individual is indeed different and they may have a different "upper level" which once exceeded causes many sexual problems... especially as you say to the older guys! Possibly, relying on the upper level set by Labs is also a mistake too... as this could be too high for some people.... great for muscle building, but not sexual function.

Even the "muscle building benefits" run into a wall.

 

[SWALE]

You cannot draw any conclusions for males from hormonal studies conducted on females. This comparative IGF-1 effect is nonsense until it is shown in males. The same goes for the Lipid Profile.

Whether one med is "stronger" or weaker" is a matter of dosing in this case, and price.