Novolin R - experience & timing

[adrenalytic]

If you're in USA, you can get Novolin R at Walmart for pretty cheap

My grocery store pharmacy has it for like $50; it's cheapest at Walmart ime

If the clerk or pharmacy tech is new, they might think it requires a prescription; you can try to assure them it doesn't and to look it up on their computer

or ask for the pharmacist, that usually gets things done.

 

[Laxman3221]

These charts mean effectively nothing to a non diabetic. 4iu of FIASP made me near hypo for 1 hour solid.

If you are on a glp1 or metformin or have good insulin sensitivity a tiny bit of insulin can fuck you up proper good.

Be careful.

They do if you know how to use insulin and how to dose. Like when people say R had two peaks, it doesn't, they just don't dose right or use it how it was designed.

And yes combining it with other Diabetic drugs and not knowing how they interact and how to dose them can put you down.

 

[AlexDavis43]

not used to combat it, used as replacement because you are not utilizing it well

My statement remains

Insulin is a shit treatment for insulin resistance; it makes it worse

As we are now seeing in abundance (GLP1s), the much more effective target is improving insulin sensitivity; injecting insulin is the antithesis

 

[rxParabolan]

My statement remains

Insulin is a shit treatment for insulin resistance; it makes it worse

As we are now seeing in abundance (GLP1s), the much more effective target is improving insulin sensitivity; injecting insulin is the antithesis

I personally use both together

 

[AlexDavis43]

These charts mean effectively nothing to a non diabetic. 4iu of FIASP made me near hypo for 1 hour solid.

If you are on a glp1 or metformin or have good insulin sensitivity a tiny bit of insulin can fuck you up proper good.

Be careful.

They do if you know how to use insulin and how to dose. Like when people say R had two peaks, it doesn't, they just don't dose right or use it how it was designed.

And yes combining it with other Diabetic drugs and not knowing how they interact and how to dose them can put you down.

Can't disagree with the FIASP comment → gotta be careful with that shit and carb timing etc

However with Novolin R, I can take 10 IU, have a light mixed meal, hit the gym for an hour, have another light mixed meal postworkout, and never go hypo

And it's not even high carb meals; the adage "10 grams of carbs per IU" I think is either outdated or Novolin R allows for much more flexibility

 

[bananafeet]

They do if you know how to use insulin and how to dose. Like when people say R had two peaks, it doesn't, they just don't dose right or use it how it was designed.

And yes combining it with other Diabetic drugs and not knowing how they interact and how to dose them can put you down.

No they don't. In normal subjects the counter regulatory hormones change the blood sugar levels and can cause swings in either direction.



In diabetics there are no responses like glucagon or insulin in response to blood sugar changes.

You can read about it here: JCI - Influence of Continuous Physiologic Hyperinsulinemia on Glucose Kinetics and Counterregulatory Hormones in Normal and Diabetic Humans