To tie everyone in here and gather hormone related validity in this thread. I recently took some Percocet (Oxycodone & Tylenol) as a replacement for my usual Norco (hydrocodone & Tylenol). I noted an improvement in erections associated for a limited time. Very limited and about long enough as the same time it took my body to identify the new opiod acting drug and go, "ehhh, ok but I see you cousin".... They are in fact very similar (as opposed to my prior belief as not very experienced). But they effect the same "Family" of opioid receptors in the body.
RAGE - One point I am vectoring on in this thread is that the ONE THING which I have discerned with over ten years of steady hydrocodone (and a few others limited), is that I can say without doubt that I get a bit "temperamental" on this drug. Flat out - It makes me hostile.... There has to be a tie-in with the action of androgen receptors as they intersect the CNS. There must be....! Last I heard it requires testosterone derivatives like androgens to experience real anger and rage. Or is that not true. Cause my wife can get pretty fucking pissed. It is rare and limited but possible. But then again that about describes the known biological component of testosterone as it relates to the female body..
It took many many years to understand that the proposed method of action of a narcotic like hydrocodone IS AT THE BRAIN DIRECTLY. Thus citing as turning off pain at the brain... I am not sure if I buy this one... I could agree that opioids are MODULATING physical perception of CONDITIONS at local tissue - but HOW??. Are you telling me that opioid receptors are ONLY in the brain? (i dont know - I am asking??) As a further distinction consider that the narcotic drug is making NO correction of FIX to the local tissue causing the pain(**Important**)
- Every seen the old bastards with shit cut off, hanging, and all fucked up over time - yet they are ok with it??
- Ever hear the old meditation thing about brain can be controlled by mere thought/meditation?
- Ever notice how while sudden trauma causes PAIN, slow action over time does not?? (**Important**)
Now / Slight tangent to conception of this thread....
I started blabbing somewhere else around here and realized I have been meaning to address this issue. Here is what I started with over there... "That's interesting timing. A buddy of mine just started on SubO apparently to control narcotics "inclinations". I always just thought of this drug as an opiate type narcotic providing pain relief type action. And for those that are not aware, or interested, Sub ox is a partial opioid receptor agonist (pain relief) AS WELL AS ANTAGONIST...!
In short, Suboxone is the "nolvadex(SERM) of opioid receptors"!!!! Meaning, it involves with the receptor, thus occupying it and technically "satiating it"(is the hypothesis here I believe), but the action is unclear. It states the drug has BOTH agonist & ant-agonist action. So what are the differences?"
** It should be pointed out the age old argument/ or recent argument of age old premise - WHERE DOES NOLVADEX EFFECT ITS RESTART ACTION? Is this estrogen like molecule circulating by the pituitary gland or hypothalamus IN THE BRAIN where its directly sensing it as "blockading action" to trick the body that there is no testosterone end product, OR are the receptors throughout the body sensing the ANTAGONISTIC EFFECTS of the molecule thus signaling the brain that there is no estrogen and thus no testosterone? The second seeming logically more correct. And YES, in lieu of Bro-Science which would have you believe that the estrogen blockade from Nolvadex is acting directly on the brain...
** I found it amusing that the pharmacological write-up on Suboxone cites CNS interaction via Opioid receptors. Whereas, none of the current literature regarding the action of Nolvadex at local receptors (Breast tissue) is effecting the body via CNS. Technically, I see this as a layman intended directive to indicate that SubOxone is working ON THE BRAIN Directly in presentation. It would appear to me that ANY drug that has a response as an adjustment of biological action via brain measurement and changed action is "CNS RELATED". I hazzard this is usually the primary method of the term "SIDE-EFFECT", but not limiting.
Its no secret I am a BIG FAN of Hydrocodone for my arthritis and more. I really don't even see much difference in Oxycodone as prepared with hydrocone and called Percocet. I think that hydro is claimed to be 1.5 times less effective than Ocycodone. Either way either one winds up back at square one - which is pain to some degree one tolerated. But there is no question I have the pain, as I have been off at times. Last year 3 alieve per day for a few days would not touch it. Totally different method of action. All what this thread is about.
A quick jump forward for now and pertaining to drugs like Alieve (Nsaids). OR NON STEROIDAL ANTI-INFLAMMATORY DRUG... While I disclaim the I AM NOT highlighting "Steroidal" as accusatory of hormone/andorgen interaction of Narcotics. And I PRESUME, the statement is indicative AS a COMPARISON for laymen as (GREEK nomenclature simplicity). As Corticosteroids ('NON-ANABOLIC") are the STAPLE of DECREASING INFLAMMATION. They just have severe side effects and thus not long term solutions. Keep in mind that "INFLAMMATION" is an effect of the INJURY most times. Whether it be a local injury the inflammation is responding to as mitigatory intended, or even a histamine (source of inflammation) reaction due to a more primary INJURY or MALFUNCTION related to SOMETHING. I don't know yet is Corticosteroids turn of the histamine system or not. I assume they do. And if you read this over and over, and if there is any correctness to what I am writing - you will surely discover this massive overlap in biological systems, significant correlations in action, certain ORDERS of activity as Responses/actions; thus soon realizing "hormones in Mens Health' - IS MUCH MORE than testosterone Measurement & application..
BUT THE POINT is that NSAIDS appear to try to 'FIX"/Mitigate the LOCAL PHYSICAL INJURY, verses Strict Control/blockade/turning off of PAIN SIGNALLING SYSTEMS - Tissue-to-CNS... A good study point would be to study whether or not NSAIDS help with Skeletal pain STRICTLY via increasing circulation by "blood thinnig". As even in lieu of an injury severe enough to trigger INFLAMMATION (which hinders blood flow). What is there to an Asprin a day? What is the REAL Action?
- How do NSAIDS work with PAIN Signalling systems of the CNS? Do they act on CNS at all in the short term? Or is pain alleviated by nsaids strickly via reduction of inflammation or return of circulation?? Is the action BRUTAL & CANNIBALISTIC as NON-Discriminating in Scope, or do NSAIDS pick certain tissues/receptors?(I'm thinking not). Are NSaids the equivalent to the SAW BLADE of a Civil War Era field "doctor" handing out bits to bite??
What about Tylenol? What is this exactly and HOW does it work. It Definitely Synergizes with narcotics meaning it AMPLIFIES the effect (not 1+1). But HOW. Is it purely the toll on the liver making it harder for the body to remove the narcotics, or is there more. Again, I's not sure how it works and it has been the last I have not even looked... They call Tylenol an "ANALGESIC" if you look it up. But they call all pain meds analgesic... Just what is Acetaminophen, HOW does it work, and WHERE IN THE HELL DID IT COME FROM. Really, is this one of the gifts from our Alien Masters which we started interacting with back in the mid 1900's...! Tylenol seems to me - to be the biggest medical mystery of them all..!!!!
"The word analgesic derives from Greek ?? – ("without") and ????? – ("pain")."
*** "James Roth, a U.S. gastroenterologist, advocated paracetamol as a gastric-friendly alternative to aspirin, which can irritate the stomach when taken without food.[3] Roth was also principal consultant to McNeil Laboratories. In 1953, McNeil Laboratories introduced Algoson, a preparation containing paracetamol together with sodium butabarbital, a sedative. In 1955, McNeil Laboratories introduced Tylenol Elixir for children, which contained paracetamol as its sole active ingredient. It was originally marketed mainly towards children, but soon came to dominate the North American pain-killer market."
"The Roswell UFO incident took place in the U.S. in June or July 1947, when an airborne object crashed on a ranch near Roswell, New Mexico"
Interesting Timing....!:drooling:
So not to get to PARANOID this early on in this thread. Lets talk about pain medication, the actual methods of their actions, the potential health indications, and how they related to both men's and women's health.. Notably, there should be a DIFFERENT END RESULT in women taking Narcotics as opposed to men - if I am correct about a hormonal interaction or possible overlap in activity.
Feel free to post thoughts and contribute. I would like to know about those on pain meds long term, and what they think.
Lastly for today. Its a very interesting POLITICAL POINT that Medical Science takes the position that hydrocodone is so dangerous and would have you gobbling NSAIDS instead. And all cause a couple of dumbshits took too much looking to get attention or kill themselves. I wonder how many suicide attempts were effected via tylenol overdose? Its a lot I guarantee. So WHY is tylenol NOT on the controlled substance list and so FEARED by all. It still gets litigated. It still pays fools for being fools. This begs the point of the MYSTERY of TYLENOL as the REASON that No one has "Classified it" is because they dont know WHAT it is, much less WHERE it even came from. I challenge anyone to find out its origins. This link gives more history, but it stinks of bullshit and omission..
[ame=http://en.wikipedia.org/wiki/Paracetamol]Paracetamol - Wikipedia, the free encyclopedia[/ame]
The point of the last words being the DEMONIZATION of Narcotics IN LIEU of dangerous drugs and for political reasons so it seems... When you say "politics" what you are saying is what someone of influence has deemed. You are talking PEOPLE..! It MAY be a large group. It may not.. Consider one small voice, the "right voice", can be readily heard IF SPOKEN WHEN THERE ARE NO OTHER VOICES SPEAKING, you are FORCED to LISTEN/OBEY, or you have no access to the "podium"....! Or YOU happen to find yourselfGagged/Bound, Paid/bought, Ignorant/stupid, Weak/dis-empowered, Unmotivated/apathetic, or just a CAPTIVE PRISONER....!
How free are we? As free as the "powers that be/PEOPLE in CONTROL" allow us to be..! How many "freedoms" are allowed to provide for social order/contentment? And in exchange for WHAT. At least Hitler put his plan on the table for all to see..!! Right???!?
Its somewhat amusing to examine the PSYCHOLOGICAL PRINCIPLE that the small loud voice gets heard.. And thus empowers its self via the mechanics of (1) Being just one oddball, (2) APPEARING "loud", (3) Singing out of turn when all else is quiet, & (4) must be answered to get it to SHUT UP....
------ THIS ------- IS -------- THE ------- FURTHEST ----- FROM ------ TRUTH ------- IN ------ REAL ------- WORLD -------ACTION ------- AND ------ PROOF ------- OF ------- MASSIVE ------- CONSPIRACY....!!!!!!!!!!!!!!!!!!!!!!!!!!! The failure of this point is proven every day....!
So then - what's your poison and DID you even really choose it....!?!???
RAGE - One point I am vectoring on in this thread is that the ONE THING which I have discerned with over ten years of steady hydrocodone (and a few others limited), is that I can say without doubt that I get a bit "temperamental" on this drug. Flat out - It makes me hostile.... There has to be a tie-in with the action of androgen receptors as they intersect the CNS. There must be....! Last I heard it requires testosterone derivatives like androgens to experience real anger and rage. Or is that not true. Cause my wife can get pretty fucking pissed. It is rare and limited but possible. But then again that about describes the known biological component of testosterone as it relates to the female body..
It took many many years to understand that the proposed method of action of a narcotic like hydrocodone IS AT THE BRAIN DIRECTLY. Thus citing as turning off pain at the brain... I am not sure if I buy this one... I could agree that opioids are MODULATING physical perception of CONDITIONS at local tissue - but HOW??. Are you telling me that opioid receptors are ONLY in the brain? (i dont know - I am asking??) As a further distinction consider that the narcotic drug is making NO correction of FIX to the local tissue causing the pain(**Important**)
- Every seen the old bastards with shit cut off, hanging, and all fucked up over time - yet they are ok with it??
- Ever hear the old meditation thing about brain can be controlled by mere thought/meditation?
- Ever notice how while sudden trauma causes PAIN, slow action over time does not?? (**Important**)
Now / Slight tangent to conception of this thread....
I started blabbing somewhere else around here and realized I have been meaning to address this issue. Here is what I started with over there... "That's interesting timing. A buddy of mine just started on SubO apparently to control narcotics "inclinations". I always just thought of this drug as an opiate type narcotic providing pain relief type action. And for those that are not aware, or interested, Sub ox is a partial opioid receptor agonist (pain relief) AS WELL AS ANTAGONIST...!
In short, Suboxone is the "nolvadex(SERM) of opioid receptors"!!!! Meaning, it involves with the receptor, thus occupying it and technically "satiating it"(is the hypothesis here I believe), but the action is unclear. It states the drug has BOTH agonist & ant-agonist action. So what are the differences?"
** It should be pointed out the age old argument/ or recent argument of age old premise - WHERE DOES NOLVADEX EFFECT ITS RESTART ACTION? Is this estrogen like molecule circulating by the pituitary gland or hypothalamus IN THE BRAIN where its directly sensing it as "blockading action" to trick the body that there is no testosterone end product, OR are the receptors throughout the body sensing the ANTAGONISTIC EFFECTS of the molecule thus signaling the brain that there is no estrogen and thus no testosterone? The second seeming logically more correct. And YES, in lieu of Bro-Science which would have you believe that the estrogen blockade from Nolvadex is acting directly on the brain...
** I found it amusing that the pharmacological write-up on Suboxone cites CNS interaction via Opioid receptors. Whereas, none of the current literature regarding the action of Nolvadex at local receptors (Breast tissue) is effecting the body via CNS. Technically, I see this as a layman intended directive to indicate that SubOxone is working ON THE BRAIN Directly in presentation. It would appear to me that ANY drug that has a response as an adjustment of biological action via brain measurement and changed action is "CNS RELATED". I hazzard this is usually the primary method of the term "SIDE-EFFECT", but not limiting.
Its no secret I am a BIG FAN of Hydrocodone for my arthritis and more. I really don't even see much difference in Oxycodone as prepared with hydrocone and called Percocet. I think that hydro is claimed to be 1.5 times less effective than Ocycodone. Either way either one winds up back at square one - which is pain to some degree one tolerated. But there is no question I have the pain, as I have been off at times. Last year 3 alieve per day for a few days would not touch it. Totally different method of action. All what this thread is about.
A quick jump forward for now and pertaining to drugs like Alieve (Nsaids). OR NON STEROIDAL ANTI-INFLAMMATORY DRUG... While I disclaim the I AM NOT highlighting "Steroidal" as accusatory of hormone/andorgen interaction of Narcotics. And I PRESUME, the statement is indicative AS a COMPARISON for laymen as (GREEK nomenclature simplicity). As Corticosteroids ('NON-ANABOLIC") are the STAPLE of DECREASING INFLAMMATION. They just have severe side effects and thus not long term solutions. Keep in mind that "INFLAMMATION" is an effect of the INJURY most times. Whether it be a local injury the inflammation is responding to as mitigatory intended, or even a histamine (source of inflammation) reaction due to a more primary INJURY or MALFUNCTION related to SOMETHING. I don't know yet is Corticosteroids turn of the histamine system or not. I assume they do. And if you read this over and over, and if there is any correctness to what I am writing - you will surely discover this massive overlap in biological systems, significant correlations in action, certain ORDERS of activity as Responses/actions; thus soon realizing "hormones in Mens Health' - IS MUCH MORE than testosterone Measurement & application..
BUT THE POINT is that NSAIDS appear to try to 'FIX"/Mitigate the LOCAL PHYSICAL INJURY, verses Strict Control/blockade/turning off of PAIN SIGNALLING SYSTEMS - Tissue-to-CNS... A good study point would be to study whether or not NSAIDS help with Skeletal pain STRICTLY via increasing circulation by "blood thinnig". As even in lieu of an injury severe enough to trigger INFLAMMATION (which hinders blood flow). What is there to an Asprin a day? What is the REAL Action?
- How do NSAIDS work with PAIN Signalling systems of the CNS? Do they act on CNS at all in the short term? Or is pain alleviated by nsaids strickly via reduction of inflammation or return of circulation?? Is the action BRUTAL & CANNIBALISTIC as NON-Discriminating in Scope, or do NSAIDS pick certain tissues/receptors?(I'm thinking not). Are NSaids the equivalent to the SAW BLADE of a Civil War Era field "doctor" handing out bits to bite??
What about Tylenol? What is this exactly and HOW does it work. It Definitely Synergizes with narcotics meaning it AMPLIFIES the effect (not 1+1). But HOW. Is it purely the toll on the liver making it harder for the body to remove the narcotics, or is there more. Again, I's not sure how it works and it has been the last I have not even looked... They call Tylenol an "ANALGESIC" if you look it up. But they call all pain meds analgesic... Just what is Acetaminophen, HOW does it work, and WHERE IN THE HELL DID IT COME FROM. Really, is this one of the gifts from our Alien Masters which we started interacting with back in the mid 1900's...! Tylenol seems to me - to be the biggest medical mystery of them all..!!!!
"The word analgesic derives from Greek ?? – ("without") and ????? – ("pain")."
*** "James Roth, a U.S. gastroenterologist, advocated paracetamol as a gastric-friendly alternative to aspirin, which can irritate the stomach when taken without food.[3] Roth was also principal consultant to McNeil Laboratories. In 1953, McNeil Laboratories introduced Algoson, a preparation containing paracetamol together with sodium butabarbital, a sedative. In 1955, McNeil Laboratories introduced Tylenol Elixir for children, which contained paracetamol as its sole active ingredient. It was originally marketed mainly towards children, but soon came to dominate the North American pain-killer market."
"The Roswell UFO incident took place in the U.S. in June or July 1947, when an airborne object crashed on a ranch near Roswell, New Mexico"
Interesting Timing....!:drooling:
So not to get to PARANOID this early on in this thread. Lets talk about pain medication, the actual methods of their actions, the potential health indications, and how they related to both men's and women's health.. Notably, there should be a DIFFERENT END RESULT in women taking Narcotics as opposed to men - if I am correct about a hormonal interaction or possible overlap in activity.
Feel free to post thoughts and contribute. I would like to know about those on pain meds long term, and what they think.
Lastly for today. Its a very interesting POLITICAL POINT that Medical Science takes the position that hydrocodone is so dangerous and would have you gobbling NSAIDS instead. And all cause a couple of dumbshits took too much looking to get attention or kill themselves. I wonder how many suicide attempts were effected via tylenol overdose? Its a lot I guarantee. So WHY is tylenol NOT on the controlled substance list and so FEARED by all. It still gets litigated. It still pays fools for being fools. This begs the point of the MYSTERY of TYLENOL as the REASON that No one has "Classified it" is because they dont know WHAT it is, much less WHERE it even came from. I challenge anyone to find out its origins. This link gives more history, but it stinks of bullshit and omission..
[ame=http://en.wikipedia.org/wiki/Paracetamol]Paracetamol - Wikipedia, the free encyclopedia[/ame]
The point of the last words being the DEMONIZATION of Narcotics IN LIEU of dangerous drugs and for political reasons so it seems... When you say "politics" what you are saying is what someone of influence has deemed. You are talking PEOPLE..! It MAY be a large group. It may not.. Consider one small voice, the "right voice", can be readily heard IF SPOKEN WHEN THERE ARE NO OTHER VOICES SPEAKING, you are FORCED to LISTEN/OBEY, or you have no access to the "podium"....! Or YOU happen to find yourselfGagged/Bound, Paid/bought, Ignorant/stupid, Weak/dis-empowered, Unmotivated/apathetic, or just a CAPTIVE PRISONER....!
How free are we? As free as the "powers that be/PEOPLE in CONTROL" allow us to be..! How many "freedoms" are allowed to provide for social order/contentment? And in exchange for WHAT. At least Hitler put his plan on the table for all to see..!! Right???!?
Its somewhat amusing to examine the PSYCHOLOGICAL PRINCIPLE that the small loud voice gets heard.. And thus empowers its self via the mechanics of (1) Being just one oddball, (2) APPEARING "loud", (3) Singing out of turn when all else is quiet, & (4) must be answered to get it to SHUT UP....
------ THIS ------- IS -------- THE ------- FURTHEST ----- FROM ------ TRUTH ------- IN ------ REAL ------- WORLD -------ACTION ------- AND ------ PROOF ------- OF ------- MASSIVE ------- CONSPIRACY....!!!!!!!!!!!!!!!!!!!!!!!!!!! The failure of this point is proven every day....!
So then - what's your poison and DID you even really choose it....!?!???
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