Paying dues, formal introduction

Hi all,
My name is Alek. I’m 185 cm, 105-120 kg, non competitive bodybuilder with a long training history. My formal education is law, however i have spent three times as much time and i have read more regarding pharmacology and I’ve been active in performance-enhancement for years with extensive personal experience running and analyzing different compounds, carriers, and protocols with myself and others. Due to my autoimmune diseases (Sle & Egpa) i have been forced to approach things with greater due-diligence putting a great emphasis on minimizing systemic inflammation from diet to lifestyle as well as the pharmacology i use. I have lurked the forums for years, joined officially in 22/23 I aim to discuss and gather data regarding various protocols and my biggest interests are:
- Gathering experiences and anecdotes from users that deploy “exotic compounds “ to their stacks ie dhb/cyp/ace, ment, new sarms, peptides/ biologics that effect growth pathways outside direct ar binding.
-Stacking strategies for long term development without compromising biomarkers and organ health
- Steroid raw handling (purification methods, storage)
- Holding sources accountable (observing and posting third party hplc tests)

Have a good one ☝️
 
Welcome to Meso.

happy pirates of the caribbean GIF
 
How old were you when you got the egpa diagnosis? Were you already training?
I got it last week officially. Ive had it since 2016 so in college. As i live in a shit hole balkan country it took me years of suffering till i personally figured it out, presented my case to the committee and got the diagnosis and on a waiting list for a biologic. Needless to say i have started it on my own (paid out of pocket) since it takes months to obtain expensive meds via insurance. I’ve struggled with severe asthma, peripheral neuropathy and nasal polyps for which they simply gave corticosteroids and inhalers without even bothering checking peripheral and tissue eosinophilic count. Then they simply blamed the lupus for Everything so it’s been a struggle. Eosinopils arent the only issue as i also have signs of overlap (Mcas) but serum Tryptase and Ige are normal so not enough for a clear cut diagnosis. I have noticed that alcohol including derivatives of benzoic acid (ba/bb) cause problems from me hence the primo source post you saw earlier. I have to make my stuff basically
 
It's pretty rare. Many doctors would just write it off as asthma without digging, it's probably lucky that you were exhibiting other symptoms for them to put it together. The lupus is a bit of a monkeywrench, lots of oldschool docs here are dismissive of it the same way they do with fibromyalgia and migraines. It is kind of weird it took this long to notice eosiniphil counts though. How high were your #s?

Based on your size you seem to be managing well. I hope you get approval for the newer meds (I'm assuming one of the -mab treatments?)

Stick around and update us on your progress. It's an interesting case, and seems like you have plenty of experience to share.
 
fibromyalgia is a hoax as it’s a diagnosis of exclusion when everything else is througy excluded which never is. I have multiple bloodworks of Eo 14-15% peripherally in blood, and multiple tissue biopsies showcasing “tissue infiltrates of eosinophils) but they never quantified them. Why tf would i bother asking for deudenal biopsy unless something is really wrong right? So essentially after gathering multiple biopsies and putting together everything (peripheral eo count, nasal polyps, asthma confirmed via metacholine test, peripheral neuropathy, and vasculitis from renal biopsy) i built the case myself. The past year i had to blend food to eat as i had urges to vommit after evey meal, throat closing like in EOE patients, tubular lesions with intact glomerular function, Anca negative. So i fit all the check marks for Egpa. The Sle is not officially confirmed but it matches the joint and skin involved. I am currently on Retuximab + Fasenra both mabs and hoping by end of this year i wouldn’t need to pay out of pocket for them.
 
Great intro post, truly. Keeping systemic inflammation to an absolute minimum should be a goal we all strive towards as inflammation seems to be a root cause of much disease. I have similar areas of interest to those you listed, and have recently dove into the peptide realm, specifically looking for peptides that offer protective properties for the heart, liver and kidneys. Haven't got too much into brain health yet, just some basic research on Semax and Selank. I'm currently using high doses of BPC-157, TB4, TB500 Frag 17-23, GHK-Cu, KPV, and Thymosin Alpha-1 in an attempt to accelerate healing of a bicep tendon tear.
 
Great intro post, truly. Keeping systemic inflammation to an absolute minimum should be a goal we all strive towards as inflammation seems to be a root cause of much disease. I have similar areas of interest to those you listed, and have recently dove into the peptide realm, specifically looking for peptides that offer protective properties for the heart, liver and kidneys. Haven't got too much into brain health yet, just some basic research on Semax and Selank. I'm currently using high doses of BPC-157, TB4, TB500 Frag 17-23, GHK-Cu, KPV, and Thymosin Alpha-1 in an attempt to accelerate healing of a bicep tendon tear.
That’s a solid stack. Look into Nad+Ss31, Ara 290 and Amino 1MQ.
 
That’s a solid stack. Look into Nad+Ss31, Ara 290 and Amino 1MQ.
Thank you! I take SS-31 daily, for my kidneys mostly, only at 6mg/day currently due to price. I do have ARA-290, but I'm not taking it as my wife uses it to treat her chronic pain and she goes through a lot. I'm also taking injectable 5 Amino 1MQ, 5mg/day, but was considering going higher. I know oral is dosed at 50mg, but heard the injectable is significantly more bioavailable. I'm sitting on a bunch of injectable SLU-PP-332, but have heard that it's stability in liquid is terrible, and that it degrades in a matter of hours. I know similar concerns were originally brought up about MOTS-C, but it turned out to last a lot longer than originally thought. Haven't gotten into researching for a definitive answer on the SLU stability yet. The vials are 5mg each, got 80 of them, and if it turns out it's not stable in liquid I guess I could try 5mg/day. Nad+ is on the list, but I keep delaying as I want to find a good brand and haven't looked into it yet.
 
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