Please help with recent blood test

[Para_33]

Genuinely curious, how did you manage to raise shbg?

Oh all the things bodybuilders regularly have In their system, DHT from test lowers Shbg the most strongly. Estradiol raises shbg.

Guys using high test, who also have high e2 keep Shbg that’s not as bad, but as soon as they add in primo or an Ai, Shbg gets crushed.

So the key is having a cycle with “high” e2 with a steroid that doesn’t decrease Shbg like DHT from test does. So nearly all steroids except Proviron have much less Shbg lowering ability than test (dht).

So using a Deca only, or any “ only “ cycle with no test, it could even be primo only, but you’d need to use exogenous injectable estradiol to keep your e2 levels where they otherwise would be on a blast dose of test.

I’ve tried it with Deca only, ( 2mg estradiol valerate IM)

tren, masteron, winstrol only (2mg estradiol valerate IM)

All of those caused shbg to keep increasing even on blast doses between 1050-1500mg per week.

The 2mg estradiol valerate keeps me e2 at around 50-60pg/ml. This is also useful because it removed the variables of the aromatization rate of test. What you inject dose wise is what you get on serum e2, so this is also convenient for that reason too.

I managed to get my Shbg from 9nmol-L up to 15 In around 3 weeks the first time I tried this.

The reason you don’t see this reported with Deca only cycles is because almost nobody has the e2 levels they would if they were using it with test. Deca doesn’t aromatize significantly if you measure with lc/ms.

So you need the e2 to push up Shbg. And to remove the DHT to prevent Shbg from being pushed back down.

I haven’t tried finasteride/dutasteride to see how this affects things, but testosterone itself has very high Shbg binding affinity itself, and thus even with finasteride/dutasteride, would still not work as well for this compared to doing Deca only, primo only etc whatever “only” cycle.

You don’t need to do this for long, a person can just do this for a few weeks or a month then reintroduce test if they feel the need. Although I never notice a difference mentally without test. I do notice that with no test in the cycle, I am noticeably not as strong even if I’m using tren or whatever else that’s known for strength.

 

[Para_33]

Genuinely curious, how did you manage to raise shbg?

Side note. I noticed that my gains plateaued to a degree even when blasting for 3-4 months when my Shbg got below 10. Restoring it, and I measurably noticed my growth rate both in body part measurement , and weight increase again when Shbg was restored.

Free androgens are obviously still by far the most important. But there is an additional Shbg receptor pathway, The working theory I have for why this is, is that it’s shown that that Shbg receptor on the cell surface, when activated by an Shbg bound steroid, that it increased the activity of the regular free androgen receptor when activated. This was shown in prostate tissue only and hasn’t been studied in muscle.

So I wanted to investigate this for myself because I’ve heard some knowledgeable guys speak about this effect. That low Shbg is good, but when it drops below a certain threshold, you lose out on that additional pathway of the Shbg receptor complex.

So when we have lots of free androgens already, and can just control that by adding more steroids, that it’s also beneficial to then have Shbg bound androgens too.

It’s reported that men taking provion get amazing sex drive, but that lasts 2-3 weeks and then drops off a cliff, and the Proviron no longer helps them libido wise. The thought is that this is because Shbg dropped below that threshold where it got too low.

But the studies are there to show the Shbg receptor enhances activity when regular free androgens bind to the regular nuclear AR

 

[Para_33]

Yes. It was supposed to be directed @para33. My apologies. But aromatase is the enzyme that converts to make estrogen. Aromatase is produced in the liver and testes. May want to consider hcg. Not sure if proviron or clomid would work but worth looking into. How long has it been since you last came off cycle and ran PCT

Based on your previous comments, i would doubt that eq is the problem. I think you are not aromatizing. Run labs and check liver enzymes. You’ve put on a lot of muscle at an unbelievable rate that even pros can’t keep up with. So if you’ve added 100 lbs of muscle in 1.5 years that means you are synthesizing almost 1.4 lbs of muscle per week! Which is double that of dudes like Ramy. Sorry buddy, I gotta call bullshit here. BTW you’d better get a heart ultrasound as well. You are in extreme danger of LVH

I do check labs often. About 2 dozen in the last 2 years. I got some before gear too. I just have very low aromatase activity. As a life time Natty I had 3-4.5 pg/ml e2 ( range 8-35) despite my total t being 450-500ng/dl. The same trend continued with injectable test.


I have pictures on my Instagram I posted real time. That also have metadata. And I have scale measurements too saved. But you can visibly see from the pictures that it’s consistent with what I’m saying.


You can look at my Instagram if you want. @parabolic_33



But when I first started bodybuilding I grew 128 to 196 in 9 months. Then cut down for 10 weeks or so down to 8%ish and stayed 196. So because I ended leaner then when I started after cutting down this was 68 lb of stage weight in 11ish months.

I have pictures to prove it that have metadata, plus I also posted them real time on my Instagram if you want to see. I’m still trying to understand why I grew so quickly. And for sure, a large part of it is because I started off at just 128lb. The growth slowed to an extent toward the end. But I also attribute it to specific things I knew how to do, that newbies otherwise wouldn’t, and you do grow faster the smaller you are. Also, Igf1, insulin, and large dose hgh I feel allowed me to make better use of the gear I was using too. Combined with just living like a pro bodybuilder full time since I’ve started. I haven’t had to work or do anything else except eat 6-7 meals a day, doing blood work, talking with other experts, gym twice a day, 9-10 hours sleep per night, etc etc.

After that first 11 months and 68lb of lean weight I cruised for 2.5 months and now I’m bulking again.

So now I’m up to 215lb 3 months into my second offseason. but it would not be pure contractile tissue because I’m in a bulk. I still have visible abs unflexed, but you can tell I have some fluff. Im by no means stage ready.

I don’t believe it’s going to be possible to grow nearly as quickly this off-season but we will see: lol but I probably will not. I’ll be insanely happy if I get to 225 at 8-10% by the end of this year.

 

[BFK]

Oh all the things bodybuilders regularly have In their system, DHT from test lowers Shbg the most strongly. Estradiol raises shbg.

Guys using high test, who also have high e2 keep Shbg that’s not as bad, but as soon as they add in primo or an Ai, Shbg gets crushed.

So the key is having a cycle with “high” e2 with a steroid that doesn’t decrease Shbg like DHT from test does. So nearly all steroids except Proviron have much less Shbg lowering ability than test (dht).

So using a Deca only, or any “ only “ cycle with no test, it could even be primo only, but you’d need to use exogenous injectable estradiol to keep your e2 levels where they otherwise would be on a blast dose of test.

I’ve tried it with Deca only, ( 2mg estradiol valerate IM)

tren, masteron, winstrol only (2mg estradiol valerate IM)

All of those caused shbg to keep increasing even on blast doses between 1050-1500mg per week.

The 2mg estradiol valerate keeps me e2 at around 50-60pg/ml. This is also useful because it removed the variables of the aromatization rate of test. What you inject dose wise is what you get on serum e2, so this is also convenient for that reason too.

I managed to get my Shbg from 9nmol-L up to 15 In around 3 weeks the first time I tried this.

The reason you don’t see this reported with Deca only cycles is because almost nobody has the e2 levels they would if they were using it with test. Deca doesn’t aromatize significantly if you measure with lc/ms.

So you need the e2 to push up Shbg. And to remove the DHT to prevent Shbg from being pushed back down.

I haven’t tried finasteride/dutasteride to see how this affects things, but testosterone itself has very high Shbg binding affinity itself, and thus even with finasteride/dutasteride, would still not work as well for this compared to doing Deca only, primo only etc whatever “only” cycle.

You don’t need to do this for long, a person can just do this for a few weeks or a month then reintroduce test if they feel the need. Although I never notice a difference mentally without test. I do notice that with no test in the cycle, I am noticeably not as strong even if I’m using tren or whatever else that’s known for strength.

I appreciate the response. Explains quite a bit, especially anecdotal evidence of “anti e’s kill gains, don’t use them unless necessary” or people swearing their gains are better from running cycles vs blasting or even something like test + deca/primo/eq and maybe an oral for 6-8 weeks, taking “off” 4 weeks, still on gh and having long esters lingering before adding aas back in for another 6-8 weeks, repeat.

As far as the outline you required and boosting SHBG with a no test protocol, ideally deca or primo only, do you think adding exogenous e2 is a necessity? Or would something such as 10-25mg dbol suffice for boosting e2?

 

[Para_33]

Where does one even acquire injectable estrogen lol

sources on here

I appreciate the response. Explains quite a bit, especially anecdotal evidence of “anti e’s kill gains, don’t use them unless necessary” or people swearing their gains are better from running cycles vs blasting or even something like test + deca/primo/eq and maybe an oral for 6-8 weeks, taking “off” 4 weeks, still on gh and having long esters lingering before adding aas back in for another 6-8 weeks, repeat.

As far as the outline you required and boosting SHBG with a no test protocol, ideally deca or primo only, do you think adding exogenous e2 is a necessity? Or would something such as 10-25mg dbol suffice for boosting e2?

dbol very well might work, but off hand I’m not familiar with the Shbg affinity of dbol. So that plus how strong the methylestradiol it produces is at raising Shbg- I just can’t say for sure because I haven’t tried it personally.

Theoretically it sounds like it could work though.

I’d personally rather use exogenous e2 because you can measure what your e2 is, and you’ll will be able to make sure your not too high/too low, where as with the dbol you won’t be able to measure it on bloodwork. But going based how you feel is still useful. Also, in general for me personally I’m not a fan of using orals consistently during growth phases because of the effect on my appetite and bloodwork. And this would be the kind of thing where you’d want 4-12 weeks of consistent estrogen levels to get your Shbg up. I’ve never used dbol ever actually, but if it’s mild enough where you will feel ok taking it daily for that time then it could work.

But yea, I attribute in part that keeping my Shbg maintained over an 11 month total offseason/prep blast to maybe be why I didn’t stall out long term. When I did stall out, it was when I tried deliberately crushing my Shbg. I got it as low as 9 nmol/L. When I got it above 14 again that’s when measurably started growing again. But I’d need better data on it to say it with more confidence. Id like somebody else to try it too for better sample size.

 

[Omi7276]

I do check labs often. About 2 dozen in the last 2 years. I got some before gear too. I just have very low aromatase activity. As a life time Natty I had 3-4.5 pg/ml e2 ( range 8-35) despite my total t being 450-500ng/dl. The same trend continued with injectable test.


I have pictures on my Instagram I posted real time. That also have metadata. And I have scale measurements too saved. But you can visibly see from the pictures that it’s consistent with what I’m saying.


You can look at my Instagram if you want. @parabolic_33



But when I first started bodybuilding I grew 128 to 196 in 9 months. Then cut down for 10 weeks or so down to 8%ish and stayed 196. So because I ended leaner then when I started after cutting down this was 68 lb of stage weight in 11ish months.

I have pictures to prove it that have metadata, plus I also posted them real time on my Instagram if you want to see. I’m still trying to understand why I grew so quickly. And for sure, a large part of it is because I started off at just 128lb. The growth slowed to an extent toward the end. But I also attribute it to specific things I knew how to do, that newbies otherwise wouldn’t, and you do grow faster the smaller you are. Also, Igf1, insulin, and large dose hgh I feel allowed me to make better use of the gear I was using too. Combined with just living like a pro bodybuilder full time since I’ve started. I haven’t had to work or do anything else except eat 6-7 meals a day, doing blood work, talking with other experts, gym twice a day, 9-10 hours sleep per night, etc etc.

After that first 11 months and 68lb of lean weight I cruised for 2.5 months and now I’m bulking again.

So now I’m up to 215lb 3 months into my second offseason. but it would not be pure contractile tissue because I’m in a bulk. I still have visible abs unflexed, but you can tell I have some fluff. Im by no means stage ready.

I don’t believe it’s going to be possible to grow nearly as quickly this off-season but we will see: lol but I probably will not. I’ll be insanely happy if I get to 225 at 8-10% by the end of this year.

@Para_33 Can you specify how you took e2v inj? 2mg all at once a week or split? Is there any way to know how much max dose of e2v can we use?
vig steve reccomends oral e2v vs inj since oral (in theory) increases SHBG more effeciently. Can you confirm or deny this claim?
Also what would be the equivalent dose for e2v tablet(oral)?
Did you ever get headaches on e2v inj or tab (possibly due to high prolactin?)
Will a low dose deca (100 mg per week) be sufficient while using e2v to recover SHBG ?
How long after your first injection did you see symptom resolution ?