Primal test C 250 and 4 IU hgh

[CarvinDC125]

No, with these theories, we're giving those who are selling us extremely under-dosed or completely false hgh the opportunity to get away with it. There are rare cases where IGF-1 doesn't increase, but they are extremely rare cases of liver failure, of insensitivity to the hormone, but they are VERY RARE CASES. Anyone here who shows up with a slightly increased IGF-1 while taking several units of GH is because they are injecting fake products! I don't care about Chase Irons, this is going in the wrong direction, we're giving those who should be selling us real products the opportunity to sell us junk, and we're silencing each other with these theories that IGF-1 doesn't always increase with GH. But don't talk nonsense, look at medical studies where there are teenagers who, with about 6 units combined with letrozole, have IGF-1 values around 700, ALL OF THEM! Here, however, there are people who inject themselves with 10 units and have 100 IGF-1 levels and blame it on low estrogen levels or a low-calorie diet. NO! It's your GH's fault, which is fake!

One way to find out for sure.
Just buy a kit and have it tested

 

[ChemBB]

I'm not saying you're wrong, but there is Jano testing on it, and that z score made a major change.

Just ignore it. I recently went through the same thing -- 6iu GH and my IGF-1 was ~130. Lots of people saying it was fake.

Then I got a GH blood test, and it was ~18ng/mL.

Thread 'IGF-1 levels of 132 on 6iu GH?'

Sep 12, 2025

So, I recently started GH for the first time. Using 6iu pre-bed.

I had my IGF-1 tested after being on it a few weeks, and my levels are lower than they were before...
Only thing I can think of is that I'm on a cut and have been using 50mg Winstrol/day which can lower IGF-1 via IGFBP.

Anyone seen something like this before? Would really hate for it to be bunk...

Growth hormone induced increase in serum IGFBP-3 level is reversed by anabolic steroids in substance abusing power athletes - PubMed

Results: While growth hormone increased the IGFBP-3 and IGF-I concentrations...

• ChemBB
• Replies: 50
• Forum: Human Growth Hormone and Peptides

• 

 

[ChemBB]

Also, this is just my $0.02, but if you feel good with your E2 at that level/not having sides, I'd leave it alone.

E2 is synergistically anabolic with androgens and has a whole bunch of important neurological/physiological benefits.

 

[Kralteramon]

High, especially supraphysiological, e2 levels suppress GH to IGF conversion. At 3x normal e2 levels, IGF being cut in half from what would be expected isn't surprising.

You've said this a couple of times. How do you explain my ~750 IGF1 on 4.5iu on 250mg test without running an AI? 127.7 pg ml estrogen (non sensitive though i think, but 17 beta estradiol nevertheless).

 

[Ghoul]

You've said this a couple of times. How do you explain my ~750 IGF1 on 4.5iu on 250mg test without running an AI? 127.7 pg ml estrogen (non sensitive though i think, but 17 beta estradiol nevertheless).

IGF is impacted by many factors.

Women can see IGF rise as estrogen levels rise, for instance. That's not because IGF conversion isn't suppressed by e2, but because estrogen stimulates more GH production, so even though conversion becomes less efficient, IGF still rises since increased GH levels are enough to overcome the lower conversion rate.

Enough pushing it up can overcome e2 pushing it down, assuming your e2 is even that high, since non-sensitive tests cross react with CRP and steroids overestimating e2.

The mechanism by which e2 suppresses IGF conversion is well documented and understood. There is nothing, anywhere, besides anecdotes backing the opposite.

 

[Kralteramon]

IGF is impacted by many factors.

Women can see IGF rise as estrogen levels rise, for instance. That's not because IGF conversion isn't suppressed by e2, but because estrogen stimulates more GH production, so even though conversion becomes less efficient, IGF still rises since increased GH levels are enough to overcome the lower conversion rate.

Enough pushing it up can overcome e2 pushing it down, assuming your e2 is even that high, since non-sensitive tests cross react with CRP and steroids overestimating e2.

The mechanism by which e2 suppresses IGF conversion is well documented and understood. There is nothing, anywhere, besides anecdotes backing the opposite.

Hmm. I guess I'm just different.