Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

I didn’t check them personally yet. I am still using the past batchs.
The stoppers aren’t silicone, it’s not something familiar among our chinese stoppers suppliers. It’s just more rigide
Could you please confirm the material identity on batches moving forward?




[Because XIANGYI is the manufacturer of the serum stopper, we can customize the color of the stopper, such as red serum stopper, gray serum stopper, pink serum stopper, Serum Stoppers in Red Natural Rubber, Gray Butyl, and Silicone, and we can customize the size of the serum stopper, such serum stopper with Straight Sided Plugs, 11mm, 13mm, and 20mm, serum bottle stoppers with Blow back finish, 20mm and 30mm.]
 
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Bacteria looks like it's the far easier problem to deal with, since Terminal Sterilization cures all failures to control living bacteria.

The main issues left I see to advising "just throw the vial in an oven at 160c for 2 hours" is verifying which compounds besides Test can withstand this temp, and which stoppers are compatible. Chlorobutyl stoppers is what USP advises compounders to use for injectables getting Terminally Sterilized because it's more heat resistant, but Bromobutyl stoppers seem to be more common in UGL because they're slightly cheaper.

Dealing with pyrogens/endotoxins is gonna be the harder nut to crack. They exist on any non-sterile surface. The longer the state of non-sterility, the more endotoxin bacteria leave behind.

They can't be effectively filtered out usually..

The way pharma deals with this is aseptic processing, keeping everything sterile so endotoxins are kept to a minimum in the finished product. Compounders are allowed to "brew" using non-sterile products, but there's a time limit from how long the ingredient becomes non-sterile that it can be used(hours). UGL raws are often non-sterile for years, so the endotoxin content (the "bioburden") must be huge. A mountain of bacteria waste.

As you pointed out deactivation takes really high product destroying temperature.

There might be another way though. There's work being done that demonstrates not all endotoxins are as dangerous as others. The worst of them might be deactivated at lower temps. If that's the case, something like 170c for 3 hours could Terminally Sterilize and deactivate the endotoxins we need to be most concerned with in one easy step.

And anyone who doesn't give a shit, thinks real men thrive on a little dirt in their gear, or believe it's all a FDA/big science hoax, can keep on doing what they do.

No one's trying to force you, unlike the tough guys who demand this discussion get shut down.
Bump.

Also....

 
Could you please confirm the material identity on batches moving forward?




[Because XIANGYI is the manufacturer of the serum stopper, we can customize the color of the stopper, such as red serum stopper, gray serum stopper, pink serum stopper, Serum Stoppers in Red Natural Rubber, Gray Butyl, and Silicone, and we can customize the size of the serum stopper, such serum stopper with Straight Sided Plugs, 11mm, 13mm, and 20mm, serum bottle stoppers with Blow back finish, 20mm and 30mm.]


Benzyl Benzoate turns silicone to goo and causes chemicals to leech into the solution making it unsuitable.

PTFE coated bromo or chloro butyl rubber is the ultimate non-reactive stopper, especially for long term storage.
 
Benzyl Benzoate turns silicone to goo and causes chemicals to leech into the solution making it unsuitable.
No leading the witness :).

 

If it puts your mind at ease, those seizures of GLPs always involve counterfeit pens or vials marked as meds. Technically an unlabeled vial filled with a non-controlled substance that's not in any way labeled for medical use is not illegal.

I haven't seen any examples of straight peptides (other than HGH) getting seized, in the US, up to now anyway.
 
If it puts your mind at ease, those seizures of GLPs always involve counterfeit pens or vials marked as meds. Technically an unlabeled vial filled with a non-controlled substance that's not in any way labeled for medical use is not illegal.

I haven't seen any examples of straight peptides (other than HGH) getting seized, in the US, up to now anyway.
The attention seems to be growing though...For those of us that are down to our last vial.... i feel like it's time for a new years promotional so we can stock up..
@Qingdao Sigma Chemicals
 
The attention seems to be growing though...For those of us that are down to our last vial.... i feel like it's time for a new years promotional so we can stock up..
@Qingdao Sigma Chemicals

I can't take the anxiety any more.

Just going to get one of those desktop peptide printers. Load it up with some aminos, choose the recipe, the next morning wake up to the smell of freshly brewed Tirz or HGH. I'm sure Alibaba knockoffs will be $99 soon enough.

IMG_9995.webpIMG_9996.webpIMG_9998.webpIMG_9997.webp
 
The attention seems to be growing though...For those of us that are down to our last vial.... i feel like it's time for a new years promotional so we can stock up..
@Qingdao Sigma Chemicals
But would we be getting the recently thoroughly tested stuff or something else (older/newer)??? I'd definitely like some of that top of the line tested product LOL.. Of course, hoping the stoppers issue is a thing of the past and the re-filtering is not necessary (being so tested-should be oil and the raw basically)

Fingers crossed lol
 
If it puts your mind at ease, those seizures of GLPs always involve counterfeit pens or vials marked as meds. Technically an unlabeled vial filled with a non-controlled substance that's not in any way labeled for medical use is not illegal.

I haven't seen any examples of straight peptides (other than HGH) getting seized, in the US, up to now anyway.
The pic you are seeing was the bust they did before they seized 15 kits of Tirz from a group buy
 

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