Qingdao Sigma HPLC testing

I don't believe the peaks should be present, especially not in that many samples. Could we email the lab to narrow it down to what substance is it?
It's time consuming for jano, he already modified this in past reports, we use both glycine and arginine for many peptides.

The unretain peak in some peptides reports are glycine or arginine we use for some of them, Arginine can interact with the protein's charged amino acid residues, such as aspartic acid and glutamic acid, in order to prevent denaturation during the drying process. Crystalline bulking agents like glycine enable primary drying at elevated temperatures and therefore decreasing the cycle time and also result in elegant lyophiles.

I don't wanna bother him again for each new report, you should get used to it:
 

Attachments

  • 1768825661812.webp
    1768825661812.webp
    7 KB · Views: 16
  • 1768825661754.webp
    1768825661754.webp
    36.3 KB · Views: 16
It's time consuming for jano, he already modified this in past reports, we use both glycine and arginine for many peptides.

The unretain peak in some peptides reports are glycine or arginine we use for some of them, Arginine can interact with the protein's charged amino acid residues, such as aspartic acid and glutamic acid, in order to prevent denaturation during the drying process. Crystalline bulking agents like glycine enable primary drying at elevated temperatures and therefore decreasing the cycle time and also result in elegant lyophiles.

I don't wanna bother him again for each new report, you should get used to it:

I believe he excludes a certain list of excipients. Could we request that he add these in?(Going forward)
 

Sponsors

Latest posts

Back
Top