Thank you.
From reading your posts it seems like you've been on Reta and Zepbound.
What do you prefer?
Only Sema and Tirz.
If I had a lot of weight to lose, I'd choose to start with Sema. It's carrot and stick. It kills "food noise", but one issue causing the majority of people to become overweight is no longer listening to hunger and satiation signals. In other words, in an environment saturated with food, getting truly "hungry" is rare. People eat on a schedule. habit, or for emotional comfort.
So even when "food noise" is silenced, many people will eat nonetheless.
When you do that with Sema, and "eat beyond your (now reduced) appetite", you will be punished, severely. Nausea, even vomiting, gastric reflux. Really terrible.
If you have half a brain, you eventually figure out the only "safe" way to eat on Sema is when you genuinely feel hunger. And even then, you need to eat slowly, small portions, and STOP the moment you feel full. No "clearing the plate" or even a single bite after you feel satisfied, or Sema, that bitch, will have you hugging the toilet again.
Sema is very much a carrot (reduced food noise) and stick (fail to observe hunger and satiety signals and you'll be physically punished) system of reprogramming. Some people never learn, and often drop out, always getting sick and never realizing why. If you obey the stop and go appetite signals you can avoid 99% of Sema sides.
Tirz lessens the "punishment" aspect. GIP is an anti-nauseant, while GLP still reduces food noise. This is a much more pleasant experience. but IMO not as brutally effective as Sema.
Reta reduces the "punishment" aspect even more, which I think will make it even less effective for the large subset of people who "need to learn the hard way", but works well for those accustomed to diet discipline, can appreciate the relief of food noise pressure, and take advantage of that to exert even more control over their diet.
So, in my opinion. Reta is best reserved for those who've already managed to condition themselves to control their diets via discipline, and can use the assistance of muted food noise so they don't have to consume energy and attention on that fight.
For those who've tried (repeatedly usually) and lost that battle, often losing weight via diet only to regain it, Tirz will work if you work with it, making it easier to lose and keep off weight. and not be too unpleasant.
For those in a rush for quickest results, on a tight budget, or the fatsos who never even tried to fight the battle against obesity, Sema is BMI boot camp with a drill sergeant wielding the spiked club needed to destroy the inner fattie, and rebuild the ability to listen to appetite signals and. better eating habits from the ground up. Once most of the weight needed to be lost is gone, graduating to Tirz for long term maintenance and potentially a few more pounds of loss is a reasonable option.
