Reta phase 3 results out

[RockyP]

https://www.fiercebiotech.com/biotech/eli-lillys-obesity-triple-threat-smashes-efficacy-expectations-phase-3-proves-intolerable

I’m waiting for commentary from @Ghoul @Photon and others. They ratcheted these poor bastards up to 12 mg daily. Can’t imagine taking that much. Efficacy was above expectations but so was discontinuation rate (again, 12 mg is nuts).

Lilly has 7 more Reta trials in the works.

 

[dinfaralt]

I'm starting to think that hsCRP is not a good indicator.

you remember me saying shit like i cant tolerate eo and its causing me high crp?

my crp basically crept up from 23 to 47 over 1-2 months and apparently i got hit by a fungus and infection at the same time.

i geniuenly believe its a dogshit marker unless you got inflammation in the body right NOW.

i have my doctor once a year scanning my heart, listening to the rhytm. doing a ekg to make sure nothing is wrong

previous to that my crp has always been 3-5

 

[Photon]

you remember me saying shit like i cant tolerate eo and its causing me high crp?

my crp basically crept up from 23 to 47 over 1-2 months and apparently i got hit by a fungus and infection at the same time.

i geniuenly believe its a dogshit marker unless you got inflammation in the body right NOW.

i have my doctor once a year scanning my heart, listening to the rhytm. doing a ekg to make sure nothing is wrong

You should get an echo, ekg done yearly,
also a full abdominal ultrasound.

keep track of lvh and prostate size

 

[dinfaralt]

You should get an echo, ekg done yearly,
also a full abdominal ultrasound.

i get it all for free, communism denmark 50% taxes woohoo

 

[maxtor]

i get it all for free, communism denmark 50% taxes woohoo

How?

 

[dinfaralt]

How?

i fart like peter griffin if he refuses

 

[New2theGame!!]

I was on 20mg reta. Backed down to 15mg. It stopped lowering my appetite a while ago no matter the dosage. Been on it over a year now.

Any plan to come off to reset receptors? I’m also on a high dose 18mgs a week and plan on increasing. Zero sides at all after getting the skin sensitivity out of the way. Sorry I do think HR has slightly increased.

 

[juicebro]

Any plan to come off to reset receptors? I’m also on a high dose 18mgs a week and plan on increasing. Zero sides at all after getting the skin sensitivity out of the way. Sorry I do think HR has slightly increased.

I tried that. Took a few weeks off. Didn't change anything.