Safety of addition of HGH in comparison to other PED

[egruberman]

I've perused all the literature I can find and have yet to find any evidence of harm for any dosage of HGH. There's a plausible mechanism of action that suggests it could encourage the growth of cancer, but I've not seen any studies indicating that.

Doesn't help that most of the research done is on HIV patients experiencing wasting. Those folks are getting 18iu a day, though and to my knowledge there's no evidence of negative effects.

 

[OmL]

And the dreams? I got crazy realistic dreams such that I nearly used it just as a "sleep-psychadelic"

I don’t remember any dreams as of late. I’m sure I’m having them but none I recall.

 

[Eddie.]

I think with the money we spend on gear and the lifestyle in general the best thing we could do is getting a full tumor marker bloodwork at least once, before we start using HGH, because cancer is no fun.

You must be very unfortunate to enhance your cancer cells with taking a replacement dose of lets say 2 IU but i'm seeing a lot of guys pushing 10IU+ and in that territory most responsible thing is taking precautionary measures IMO.

With that being said, i think HGH would be a safer and better addition to a mid level cycle instead of pushing aas even higher for the extra growth. Most significant downsides i see is costwise and the inconvenience to take it everyday full year round. I see many complaining for more frequent test pins and more guys wanna try test U for once a week or 2 weeks pin while cruising but pinning everyday or multiple times a day with something you need access to a fridge is the real pain in the ass.

 

[phenominal34]

So does my father in law, and he doesn't take anything.

Post your father in law next to Stallone lol let us compare lol

 

[Avies48]

Dont forget how much damage hgh can do to ur body tho… kidney issues, renal (eye) issues, hematocrit, hemaglobin (yes hgh can and will effect ur blood thickness) , diabetusss, enlarged heart, head.. hands, feet edema… migraines… optical nerve pressure, blood sugar issues… blood pressure, etc etc

Ffs… its not like its safer than testosterone… or anything else for that matter

Why anyone would want to combat the sides that could occur when u could actually just diet??

But i still wanna try some myself haha just to see

 

[amazonas]

I think the cancer has more to do with hightened IGF1 levels than anything. Big people don't live for long. Take for example fasting, it is associated with an increase in HGH and a decrease in IGF1 which promotes longevity. High IGF1 levels are not healthy.

 

[OldGHGuy]

Dont forget how much damage hgh can do to ur body tho… kidney issues, renal (eye) issues, hematocrit, hemaglobin (yes hgh can and will effect ur blood thickness) , diabetusss, enlarged heart, head.. hands, feet edema… migraines… optical nerve pressure, blood sugar issues… blood pressure, etc etc

Ffs… its not like its safer than testosterone… or anything else for that matter

Why anyone would want to combat the sides that could occur when u could actually just diet??

But i still wanna try some myself haha just to see

Im a 2-3iu user and see basically NO sides other than a little water retention so it is very person/dose dependant.

 

[UncleBuns]

The difference between my natural production and 2 - 2.5 IU daily is wild. I think I'm a low GH producer as natural IGF is about 110 but I get 100 point IGF per IU GH. This effect is with same level of training, calorie intake, diet, etc. My recovery, sense of well being, aesthetics are greatly increases by even 2 IU. The only downside is that even 2 IU raises my A1c even when cutting. I believe this negative effect is genetic. I use metformin with it to mitigate this effect.

I would like to think GH at a reasonable dose, say 2- 4 IU is safer than additional androgens but I think it is dose and person dependent. For example I've seen an increase in my A1c from 2.2iu daily that is not acceptable to me. 150mg mast on top of TRT has shown no change in any health markers for me. I tend to believe that any extra androgen or GH above natural level has the potential to have negative health effects. I think every compound is person specific and dose-dependent. I have not looked into GH enough to have an informed opinion but I can't imagine taking 5 or higher IU GH is a free ride with no negatives. Biology rarely works that way. There's no free lunch.

 

[Eddie.]

The difference between my natural production and 2 - 2.5 IU daily is wild. I think I'm a low GH producer as natural IGF is about 110 but I get 100 point IGF per IU GH. This effect is with same level of training, calorie intake, diet, etc. My recovery, sense of well being, aesthetics are greatly increases by even 2 IU. The only downside is that even 2 IU raises my A1c even when cutting. I believe this negative effect is genetic. I use metformin with it to mitigate this effect.

I would like to think GH at a reasonable dose, say 2- 4 IU is safer than additional androgens but I think it is dose and person dependent. For example I've seen an increase in my A1c from 2.2iu daily that is not acceptable to me. 150mg mast on top of TRT has shown no change in any health markers for me. I tend to believe that any extra androgen or GH above natural level has the potential to have negative health effects. I think every compound is person specific and dose-dependent. I have not looked into GH enough to have an informed opinion but I can't imagine taking 5 or higher IU GH is a free ride with no negatives. Biology rarely works that way. There's no free lunch.

Interesting! How's the baseline A1c while cutting and how it ends up with HGH? Do you use Metformin the whole time you run HGH?

 

[Spaceman Spiff]

Dont forget how much damage hgh can do to ur body tho… kidney issues, renal (eye) issues, hematocrit, hemaglobin (yes hgh can and will effect ur blood thickness) , diabetusss, enlarged heart, head.. hands, feet edema… migraines… optical nerve pressure, blood sugar issues… blood pressure, etc etc

Ffs… its not like its safer than testosterone… or anything else for that matter

Why anyone would want to combat the sides that could occur when u could actually just diet??

But i still wanna try some myself haha just to see

Those sides are definitely blown out of proportion imo. Especially at 3-4iu. When you run it, you will see

 

[UncleBuns]

Interesting! How's the baseline A1c while cutting and how it ends up with HGH? Do you use Metformin the whole time you run HGH?

Without spending the time digging through the old labs normal baseline was 5.1 or 5.2 for years. 2.2 IU for some months had it at just next to "pre diabetic" level, 5.6ish. I take metformin based on how much GH I'm using. For 2.2ish IU 250mg xr nightly, 3ish IU 500mg, 4ish IU 750, etc. 4 is the highest I go and not sure if I'll go above 3.5ish anymore. I get a lot of water retention from GH and 4 gets me way more watery than I like.

 

[patriotmuscle1]

I can agree with safer and healthier absolutely. But for me and a large amount of guys I talk to and shit.. we all had no big gains from from 3-8ius of gh.. I mean recovery and fullness/pump always better yes. If someone wanted to grow I would not recommend gh personally. I think gh is better used a little further down the journey.. I mean it all depends on goals and budget.
1-3 compounds stacked will get way better results the test+gh.. I rather run 2 compounds and use the gh money for more quality food.. more whey isolate.
If you got money to kinda burn.. run gh all year lol.. but if all your buddies are alot bigger because they ran test/Nandrolone or test/primo-mast don't be upset.. lol.. idk I'm goofing around now..
It all depends on goals..if health is number 1 and not gains.. sure.. but you can run 1-3 compounds.. upt to like 1-3grams a wk .. and have ok to decent blood work as long as you do all you can to mitigate all negative possibilities. Some people can't run shit without blood work going to shit.. some of us me including can get away with a fair amount..
If my younger brother came to me roght now and was 100% all in .. I wouldn't bother with gh right away at all.. just test. Maybe test /npp next time or mast/primo.. I'd probably not worry about gh much to start. Focus on those.welll known compounds for good gains and focus on diet, training, rest, and supplements in that order mostly. Let me know if I'm crazy fellas.. idk

 

[Eddie.]

Without spending the time digging through the old labs normal baseline was 5.1 or 5.2 for years. 2.2 IU for some months had it at just next to "pre diabetic" level, 5.6ish. I take metformin based on how much GH I'm using. For 2.2ish IU 250mg xr nightly, 3ish IU 500mg, 4ish IU 750, etc. 4 is the highest I go and not sure if I'll go above 3.5ish anymore. I get a lot of water retention from GH and 4 gets me way more watery than I like.

Right, 5,6 ain't good. For me personally before i start gear i was at 5,6 and 3 months after just 210 Test and 500mg berberine per day without changing my diet it came down to 5,0. I don't know which helped more but i'm guessing the Test. Berberine is a great tool though and you can go up to 1500mg with less side effects than metformin afaik.

 

[Sector]

Negative sides are:
-increased resting heart rate
-Increased Blood sugar
-Increased insulin resistance
-enlarged heart
-potentially accelerated cancer risk if cancer cells are already present (to my understanding it doesn't create cancer, just accelerates the cell growth if it's already there)

..and probably some others im failing to mention. Those are just the one's at forefront of my mind

Obviously a lot of this is dose dependent, similar to gear. The lower the dose, the less likelihood of sides. The higher the dose, the increased like hood of sides

That said, a lot of the sides can be negated with diet and cardio (such as the blood sugar, insulin resistance, and heart rate). For higher dosages of GH, ancillary products are beneficial to help negate some the sides, and insulin is probably needed at very* high doses if diet, cardio, GLP-1s and metformin aren't doing enough for blood glucose

I'm on 6iu/day and have had no side effects other than some slight water retention in the abdomen area. Blood sugar is under control, but I also do a lot of cardio, a low carb diet, and I'm taking tirzepatide (GLP-1 Agonist), along with 1000mg metformin a day (been experimenting with metformin fasted in the morning with cardio, and at night before bed--don't really notice any difference in effects with the varied timings of it)

 

[jayteelif87]

I would actually argue that it’s not safer than many.. safer than tren? For sure. But the primary risk of HGH is the replication of cancer cells, and that’s a pretty big risk in comparison to increased RBC or skewed hematicrit.

That being said, I run 10iu a day.. so take it for what you will.

This was actually recently proven to be false. See more recent meta-study of all previous (outdated) studies that shows Growth hormone replacement therapy reduces the risk of cancer in adults with growth hormone deficiency: A meta-analysis.

 

[laclark89]

Those sides are definitely blown out of proportion imo. Especially at 3-4iu. When you run it, you will see

I get no sides from 3-4 iu.

I think if you have the money for it, have good Natty t levels, are unsure about anabolics or very worried about sexual reproduction harm. 3-4 iu solo would be be a smart first cycle. See what happens. No shut down no acne no ed.

Even better like you side first cycle 500 2nd 500 + 3iu

Shit a new user if they have low natty t
Even 300mg and 3 iu should be a great start.

 

[nightprowler7]

this is why I brought it up actually.


thats if you do have cancer.

Interesting article. I came across and an oncologist who discussed this.

Association Between Recombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk in Childhood: Systematic Review and Meta-Analysis - PMC

The safety of recombinant human growth hormone (rhGH) treatment in childhood and the role of rhGH therapy in promoting tumorigenesis and progression have been the subject of debate for decades. We aimed to systematically assess the relationship ...

www.ncbi.nlm.nih.gov

Most people don't know they have cancer because they don't get checked and have no symptoms

 

[Spaceman Spiff]

Most people don't know they have cancer because they don't get checked and have no symptoms

That's true. How many people here do blood work to check if they have anything wrong with them prior to running GH too?( I know cancer screening goes past blood work)